| Full name: peroxisomal membrane protein 4 | Alias Symbol: PMP24 | ||
| Type: protein-coding gene | Cytoband: 20q11.22 | ||
| Entrez ID: 11264 | HGNC ID: HGNC:15920 | Ensembl Gene: ENSG00000101417 | OMIM ID: 616397 |
| Drug and gene relationship at DGIdb | |||
Expression of PXMP4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PXMP4 | 11264 | 219428_s_at | 0.4190 | 0.3155 | |
| GSE20347 | PXMP4 | 11264 | 219428_s_at | -0.0166 | 0.9039 | |
| GSE23400 | PXMP4 | 11264 | 219428_s_at | -0.0283 | 0.5817 | |
| GSE26886 | PXMP4 | 11264 | 219428_s_at | -0.1062 | 0.6022 | |
| GSE29001 | PXMP4 | 11264 | 219428_s_at | 0.0698 | 0.8174 | |
| GSE38129 | PXMP4 | 11264 | 219428_s_at | 0.0396 | 0.7155 | |
| GSE45670 | PXMP4 | 11264 | 219428_s_at | 0.2048 | 0.2483 | |
| GSE53622 | PXMP4 | 11264 | 94638 | -0.0467 | 0.6761 | |
| GSE53624 | PXMP4 | 11264 | 94638 | 0.1272 | 0.2058 | |
| GSE63941 | PXMP4 | 11264 | 219428_s_at | 0.3901 | 0.5046 | |
| GSE77861 | PXMP4 | 11264 | 219428_s_at | -0.0282 | 0.9494 | |
| GSE97050 | PXMP4 | 11264 | A_23_P91430 | 0.0893 | 0.8195 | |
| SRP007169 | PXMP4 | 11264 | RNAseq | -0.9498 | 0.0122 | |
| SRP008496 | PXMP4 | 11264 | RNAseq | -0.4087 | 0.0957 | |
| SRP064894 | PXMP4 | 11264 | RNAseq | 0.2883 | 0.2268 | |
| SRP133303 | PXMP4 | 11264 | RNAseq | -0.2756 | 0.0285 | |
| SRP159526 | PXMP4 | 11264 | RNAseq | -0.2702 | 0.2453 | |
| SRP193095 | PXMP4 | 11264 | RNAseq | -0.3179 | 0.0002 | |
| SRP219564 | PXMP4 | 11264 | RNAseq | -0.0621 | 0.8459 | |
| TCGA | PXMP4 | 11264 | RNAseq | -0.3340 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PXMP4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PXMP4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PXMP4 | 11264 | 15 | 0 | 15 | |
| GSE20123 | PXMP4 | 11264 | 15 | 0 | 15 | |
| GSE43470 | PXMP4 | 11264 | 12 | 0 | 31 | |
| GSE46452 | PXMP4 | 11264 | 29 | 0 | 30 | |
| GSE47630 | PXMP4 | 11264 | 24 | 1 | 15 | |
| GSE54993 | PXMP4 | 11264 | 0 | 19 | 51 | |
| GSE54994 | PXMP4 | 11264 | 25 | 1 | 27 | |
| GSE60625 | PXMP4 | 11264 | 0 | 0 | 11 | |
| GSE74703 | PXMP4 | 11264 | 11 | 0 | 25 | |
| GSE74704 | PXMP4 | 11264 | 10 | 0 | 10 | |
| TCGA | PXMP4 | 11264 | 51 | 1 | 44 |
Total number of gains: 192; Total number of losses: 22; Total Number of normals: 274.
Somatic mutations of PXMP4:
Generating mutation plots.
Highly correlated genes for PXMP4:
Showing top 20/132 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PXMP4 | MBD4 | 0.77408 | 3 | 0 | 3 |
| PXMP4 | A1BG | 0.772575 | 3 | 0 | 3 |
| PXMP4 | CSNK2A2 | 0.744982 | 3 | 0 | 3 |
| PXMP4 | ERGIC1 | 0.74003 | 3 | 0 | 3 |
| PXMP4 | MBOAT2 | 0.732413 | 3 | 0 | 3 |
| PXMP4 | TEX261 | 0.728167 | 3 | 0 | 3 |
| PXMP4 | STK35 | 0.726753 | 3 | 0 | 3 |
| PXMP4 | RAB13 | 0.701516 | 4 | 0 | 3 |
| PXMP4 | DCTN3 | 0.699292 | 3 | 0 | 3 |
| PXMP4 | SFT2D2 | 0.681823 | 3 | 0 | 3 |
| PXMP4 | FAM49B | 0.672473 | 3 | 0 | 3 |
| PXMP4 | COL5A3 | 0.666308 | 3 | 0 | 3 |
| PXMP4 | ACP2 | 0.660007 | 3 | 0 | 3 |
| PXMP4 | RNF149 | 0.656482 | 3 | 0 | 3 |
| PXMP4 | SMARCAL1 | 0.655641 | 3 | 0 | 3 |
| PXMP4 | STAU1 | 0.653735 | 4 | 0 | 3 |
| PXMP4 | MYH10 | 0.653449 | 3 | 0 | 3 |
| PXMP4 | TOX4 | 0.652909 | 4 | 0 | 3 |
| PXMP4 | MRPS18B | 0.652424 | 4 | 0 | 3 |
| PXMP4 | MTSS1 | 0.651494 | 4 | 0 | 3 |
For details and further investigation, click here
