| Full name: acyl-CoA dehydrogenase short/branched chain | Alias Symbol: SBCAD|ACAD7 | ||
| Type: protein-coding gene | Cytoband: 10q26.13 | ||
| Entrez ID: 36 | HGNC ID: HGNC:91 | Ensembl Gene: ENSG00000196177 | OMIM ID: 600301 |
| Drug and gene relationship at DGIdb | |||
Expression of ACADSB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACADSB | 36 | 205355_at | -0.6129 | 0.1227 | |
| GSE20347 | ACADSB | 36 | 205355_at | -0.5428 | 0.0002 | |
| GSE23400 | ACADSB | 36 | 205355_at | -0.1450 | 0.0000 | |
| GSE26886 | ACADSB | 36 | 205355_at | -1.1800 | 0.0009 | |
| GSE29001 | ACADSB | 36 | 205355_at | -0.9518 | 0.0021 | |
| GSE38129 | ACADSB | 36 | 205355_at | -0.6232 | 0.0003 | |
| GSE45670 | ACADSB | 36 | 226030_at | -1.0835 | 0.0008 | |
| GSE53622 | ACADSB | 36 | 109092 | -1.0643 | 0.0000 | |
| GSE53624 | ACADSB | 36 | 109092 | -1.0162 | 0.0000 | |
| GSE63941 | ACADSB | 36 | 226030_at | -1.9819 | 0.0037 | |
| GSE77861 | ACADSB | 36 | 205355_at | -0.6548 | 0.0280 | |
| GSE97050 | ACADSB | 36 | A_23_P158570 | -0.4933 | 0.2945 | |
| SRP007169 | ACADSB | 36 | RNAseq | -1.7136 | 0.0000 | |
| SRP008496 | ACADSB | 36 | RNAseq | -1.2425 | 0.0000 | |
| SRP064894 | ACADSB | 36 | RNAseq | -0.9261 | 0.0001 | |
| SRP133303 | ACADSB | 36 | RNAseq | -0.0623 | 0.7137 | |
| SRP159526 | ACADSB | 36 | RNAseq | -0.1649 | 0.6521 | |
| SRP193095 | ACADSB | 36 | RNAseq | -0.0688 | 0.4858 | |
| SRP219564 | ACADSB | 36 | RNAseq | -0.7803 | 0.0200 | |
| TCGA | ACADSB | 36 | RNAseq | -0.6589 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by ACADSB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACADSB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACADSB | 36 | 1 | 6 | 23 | |
| GSE20123 | ACADSB | 36 | 1 | 6 | 23 | |
| GSE43470 | ACADSB | 36 | 0 | 9 | 34 | |
| GSE46452 | ACADSB | 36 | 0 | 11 | 48 | |
| GSE47630 | ACADSB | 36 | 2 | 14 | 24 | |
| GSE54993 | ACADSB | 36 | 8 | 1 | 61 | |
| GSE54994 | ACADSB | 36 | 1 | 9 | 43 | |
| GSE60625 | ACADSB | 36 | 0 | 0 | 11 | |
| GSE74703 | ACADSB | 36 | 0 | 6 | 30 | |
| GSE74704 | ACADSB | 36 | 1 | 2 | 17 | |
| TCGA | ACADSB | 36 | 4 | 28 | 64 |
Total number of gains: 18; Total number of losses: 92; Total Number of normals: 378.
Somatic mutations of ACADSB:
Generating mutation plots.
Highly correlated genes for ACADSB:
Showing top 20/1266 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACADSB | NAA35 | 0.830522 | 3 | 0 | 3 |
| ACADSB | ATF7 | 0.771203 | 3 | 0 | 3 |
| ACADSB | UHRF1BP1L | 0.762588 | 3 | 0 | 3 |
| ACADSB | NBN | 0.75048 | 3 | 0 | 3 |
| ACADSB | GPD1L | 0.747759 | 11 | 0 | 11 |
| ACADSB | CPEB2 | 0.744611 | 3 | 0 | 3 |
| ACADSB | PDIK1L | 0.727102 | 5 | 0 | 5 |
| ACADSB | HADH | 0.720875 | 5 | 0 | 4 |
| ACADSB | DIS3L | 0.718286 | 4 | 0 | 4 |
| ACADSB | LYRM7 | 0.706867 | 5 | 0 | 5 |
| ACADSB | NLGN4Y | 0.706675 | 3 | 0 | 3 |
| ACADSB | LRRK2 | 0.702175 | 7 | 0 | 7 |
| ACADSB | HMGN1 | 0.699818 | 3 | 0 | 3 |
| ACADSB | TMEM126A | 0.69295 | 3 | 0 | 3 |
| ACADSB | BLOC1S2 | 0.691495 | 4 | 0 | 4 |
| ACADSB | PPP1R3D | 0.68783 | 3 | 0 | 3 |
| ACADSB | ZNF791 | 0.68588 | 3 | 0 | 3 |
| ACADSB | PKD2 | 0.684722 | 3 | 0 | 3 |
| ACADSB | EEPD1 | 0.684042 | 5 | 0 | 4 |
| ACADSB | PTGER2 | 0.683573 | 3 | 0 | 3 |
For details and further investigation, click here
