| Full name: ATPase phospholipid transporting 8B3 | Alias Symbol: ATPIK | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 148229 | HGNC ID: HGNC:13535 | Ensembl Gene: ENSG00000130270 | OMIM ID: 605866 |
| Drug and gene relationship at DGIdb | |||
Expression of ATP8B3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATP8B3 | 148229 | 1554704_at | 0.1317 | 0.8117 | |
| GSE20347 | ATP8B3 | 148229 | 215319_at | 0.0079 | 0.9007 | |
| GSE23400 | ATP8B3 | 148229 | 215319_at | -0.0835 | 0.0033 | |
| GSE26886 | ATP8B3 | 148229 | 239457_at | 0.9177 | 0.0000 | |
| GSE29001 | ATP8B3 | 148229 | 215319_at | -0.0082 | 0.9544 | |
| GSE38129 | ATP8B3 | 148229 | 215319_at | -0.0703 | 0.2758 | |
| GSE45670 | ATP8B3 | 148229 | 1554704_at | 0.3691 | 0.0390 | |
| GSE53622 | ATP8B3 | 148229 | 21057 | 0.6791 | 0.0000 | |
| GSE53624 | ATP8B3 | 148229 | 99324 | 1.0409 | 0.0000 | |
| GSE63941 | ATP8B3 | 148229 | 1554704_at | 0.1134 | 0.7731 | |
| GSE77861 | ATP8B3 | 148229 | 1554704_at | -0.0143 | 0.9067 | |
| GSE97050 | ATP8B3 | 148229 | A_23_P79108 | 0.0565 | 0.7782 | |
| SRP064894 | ATP8B3 | 148229 | RNAseq | 1.2481 | 0.0000 | |
| SRP133303 | ATP8B3 | 148229 | RNAseq | 0.7847 | 0.0056 | |
| SRP159526 | ATP8B3 | 148229 | RNAseq | 0.8644 | 0.0674 | |
| SRP193095 | ATP8B3 | 148229 | RNAseq | 1.1864 | 0.0000 | |
| SRP219564 | ATP8B3 | 148229 | RNAseq | 2.5103 | 0.0001 | |
| TCGA | ATP8B3 | 148229 | RNAseq | 0.9954 | 0.0000 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by ATP8B3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATP8B3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATP8B3 | 148229 | 4 | 6 | 20 | |
| GSE20123 | ATP8B3 | 148229 | 4 | 5 | 21 | |
| GSE43470 | ATP8B3 | 148229 | 1 | 10 | 32 | |
| GSE46452 | ATP8B3 | 148229 | 47 | 1 | 11 | |
| GSE47630 | ATP8B3 | 148229 | 5 | 7 | 28 | |
| GSE54993 | ATP8B3 | 148229 | 16 | 3 | 51 | |
| GSE54994 | ATP8B3 | 148229 | 8 | 15 | 30 | |
| GSE60625 | ATP8B3 | 148229 | 9 | 0 | 2 | |
| GSE74703 | ATP8B3 | 148229 | 1 | 7 | 28 | |
| GSE74704 | ATP8B3 | 148229 | 3 | 3 | 14 | |
| TCGA | ATP8B3 | 148229 | 6 | 25 | 65 |
Total number of gains: 104; Total number of losses: 82; Total Number of normals: 302.
Somatic mutations of ATP8B3:
Generating mutation plots.
Highly correlated genes for ATP8B3:
Showing top 20/407 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATP8B3 | ADRA2C | 0.73948 | 3 | 0 | 3 |
| ATP8B3 | CCDC33 | 0.727432 | 3 | 0 | 3 |
| ATP8B3 | CELF3 | 0.716435 | 4 | 0 | 3 |
| ATP8B3 | FCN2 | 0.710256 | 4 | 0 | 4 |
| ATP8B3 | OPRK1 | 0.709814 | 4 | 0 | 4 |
| ATP8B3 | SCGN | 0.707792 | 3 | 0 | 3 |
| ATP8B3 | NOS1 | 0.702499 | 3 | 0 | 3 |
| ATP8B3 | CLCN1 | 0.700743 | 3 | 0 | 3 |
| ATP8B3 | B3GALT1 | 0.698645 | 4 | 0 | 4 |
| ATP8B3 | CLDN9 | 0.69849 | 5 | 0 | 5 |
| ATP8B3 | AQP6 | 0.696945 | 4 | 0 | 4 |
| ATP8B3 | NCR2 | 0.696681 | 4 | 0 | 4 |
| ATP8B3 | CITED1 | 0.695825 | 3 | 0 | 3 |
| ATP8B3 | KIR2DS3 | 0.694946 | 4 | 0 | 4 |
| ATP8B3 | EFNA3 | 0.691469 | 5 | 0 | 4 |
| ATP8B3 | HTR1A | 0.691363 | 3 | 0 | 3 |
| ATP8B3 | BLK | 0.686258 | 3 | 0 | 3 |
| ATP8B3 | BCAN | 0.683396 | 3 | 0 | 3 |
| ATP8B3 | PSG9 | 0.682383 | 5 | 0 | 5 |
| ATP8B3 | LIF | 0.680188 | 3 | 0 | 3 |
For details and further investigation, click here
