| Full name: nuclear transcription factor Y subunit beta | Alias Symbol: CBF-A|HAP3|NF-YB | ||
| Type: protein-coding gene | Cytoband: 12q23.3 | ||
| Entrez ID: 4801 | HGNC ID: HGNC:7805 | Ensembl Gene: ENSG00000120837 | OMIM ID: 189904 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
NFYB involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04612 | Antigen processing and presentation | |
| hsa05152 | Tuberculosis |
Expression of NFYB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NFYB | 4801 | 218127_at | -0.3503 | 0.7069 | |
| GSE20347 | NFYB | 4801 | 218127_at | 0.2943 | 0.1333 | |
| GSE23400 | NFYB | 4801 | 218127_at | 0.2257 | 0.0181 | |
| GSE26886 | NFYB | 4801 | 218127_at | -0.0872 | 0.8140 | |
| GSE29001 | NFYB | 4801 | 218127_at | 0.4459 | 0.0618 | |
| GSE38129 | NFYB | 4801 | 218127_at | 0.1820 | 0.4141 | |
| GSE45670 | NFYB | 4801 | 218127_at | -0.5460 | 0.0046 | |
| GSE53622 | NFYB | 4801 | 34045 | 0.1320 | 0.2097 | |
| GSE53624 | NFYB | 4801 | 34045 | 0.1660 | 0.0642 | |
| GSE63941 | NFYB | 4801 | 218127_at | -0.3648 | 0.4248 | |
| GSE77861 | NFYB | 4801 | 218127_at | 0.3300 | 0.2772 | |
| GSE97050 | NFYB | 4801 | A_23_P53668 | -0.0883 | 0.8190 | |
| SRP007169 | NFYB | 4801 | RNAseq | 0.7356 | 0.0913 | |
| SRP008496 | NFYB | 4801 | RNAseq | 0.9709 | 0.0016 | |
| SRP064894 | NFYB | 4801 | RNAseq | 0.2525 | 0.0482 | |
| SRP133303 | NFYB | 4801 | RNAseq | 0.5693 | 0.0037 | |
| SRP159526 | NFYB | 4801 | RNAseq | 0.5155 | 0.0159 | |
| SRP193095 | NFYB | 4801 | RNAseq | 0.1671 | 0.1070 | |
| SRP219564 | NFYB | 4801 | RNAseq | -0.1043 | 0.8318 | |
| TCGA | NFYB | 4801 | RNAseq | 0.0117 | 0.8244 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NFYB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NFYB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NFYB | 4801 | 4 | 2 | 24 | |
| GSE20123 | NFYB | 4801 | 4 | 2 | 24 | |
| GSE43470 | NFYB | 4801 | 2 | 0 | 41 | |
| GSE46452 | NFYB | 4801 | 9 | 1 | 49 | |
| GSE47630 | NFYB | 4801 | 9 | 1 | 30 | |
| GSE54993 | NFYB | 4801 | 0 | 5 | 65 | |
| GSE54994 | NFYB | 4801 | 4 | 2 | 47 | |
| GSE60625 | NFYB | 4801 | 0 | 0 | 11 | |
| GSE74703 | NFYB | 4801 | 2 | 0 | 34 | |
| GSE74704 | NFYB | 4801 | 1 | 2 | 17 | |
| TCGA | NFYB | 4801 | 19 | 11 | 66 |
Total number of gains: 54; Total number of losses: 26; Total Number of normals: 408.
Somatic mutations of NFYB:
Generating mutation plots.
Highly correlated genes for NFYB:
Showing top 20/819 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NFYB | RBM24 | 0.735198 | 3 | 0 | 3 |
| NFYB | MAPK10 | 0.732397 | 3 | 0 | 3 |
| NFYB | FILIP1 | 0.732251 | 3 | 0 | 3 |
| NFYB | DTNA | 0.731781 | 3 | 0 | 3 |
| NFYB | CCDC146 | 0.7311 | 3 | 0 | 3 |
| NFYB | WDR92 | 0.729012 | 3 | 0 | 3 |
| NFYB | BUB3 | 0.723074 | 3 | 0 | 3 |
| NFYB | TMEM181 | 0.716965 | 3 | 0 | 3 |
| NFYB | IL17RD | 0.710669 | 3 | 0 | 3 |
| NFYB | CBLL1 | 0.709502 | 3 | 0 | 3 |
| NFYB | ACSS3 | 0.705959 | 3 | 0 | 3 |
| NFYB | ST6GALNAC3 | 0.698407 | 3 | 0 | 3 |
| NFYB | GMCL1 | 0.696641 | 3 | 0 | 3 |
| NFYB | ACP6 | 0.686143 | 4 | 0 | 3 |
| NFYB | VPS36 | 0.683622 | 3 | 0 | 3 |
| NFYB | RAB9B | 0.683336 | 3 | 0 | 3 |
| NFYB | GDPD1 | 0.681202 | 5 | 0 | 4 |
| NFYB | ANK2 | 0.679291 | 5 | 0 | 4 |
| NFYB | KLHL15 | 0.676677 | 7 | 0 | 5 |
| NFYB | UXS1 | 0.675051 | 3 | 0 | 3 |
For details and further investigation, click here
