| Full name: lymphocyte antigen 6 family member G6C | Alias Symbol: G6c|NG24 | ||
| Type: protein-coding gene | Cytoband: 6p21.33 | ||
| Entrez ID: 80740 | HGNC ID: HGNC:13936 | Ensembl Gene: ENSG00000204421 | OMIM ID: 610435 |
| Drug and gene relationship at DGIdb | |||
Expression of LY6G6C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LY6G6C | 80740 | 207114_at | -0.9479 | 0.3157 | |
| GSE20347 | LY6G6C | 80740 | 207114_at | -1.4437 | 0.0000 | |
| GSE23400 | LY6G6C | 80740 | 207114_at | -0.7078 | 0.0000 | |
| GSE26886 | LY6G6C | 80740 | 207114_at | -1.5563 | 0.0000 | |
| GSE29001 | LY6G6C | 80740 | 207114_at | -1.2237 | 0.0158 | |
| GSE38129 | LY6G6C | 80740 | 207114_at | -1.0028 | 0.0029 | |
| GSE45670 | LY6G6C | 80740 | 207114_at | -1.0251 | 0.0021 | |
| GSE53622 | LY6G6C | 80740 | 22097 | -0.9198 | 0.0000 | |
| GSE53624 | LY6G6C | 80740 | 22097 | -1.3075 | 0.0000 | |
| GSE63941 | LY6G6C | 80740 | 207114_at | 0.2543 | 0.4052 | |
| GSE77861 | LY6G6C | 80740 | 207114_at | -1.0542 | 0.0819 | |
| GSE97050 | LY6G6C | 80740 | A_23_P8083 | -0.0275 | 0.9143 | |
| SRP007169 | LY6G6C | 80740 | RNAseq | -2.5225 | 0.0000 | |
| SRP064894 | LY6G6C | 80740 | RNAseq | -2.0927 | 0.0007 | |
| SRP133303 | LY6G6C | 80740 | RNAseq | -2.3632 | 0.0005 | |
| SRP159526 | LY6G6C | 80740 | RNAseq | -1.5861 | 0.1360 | |
| TCGA | LY6G6C | 80740 | RNAseq | 0.7469 | 0.1045 |
Upregulated datasets: 0; Downregulated datasets: 9.
Survival by LY6G6C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LY6G6C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LY6G6C | 80740 | 5 | 1 | 24 | |
| GSE20123 | LY6G6C | 80740 | 5 | 1 | 24 | |
| GSE43470 | LY6G6C | 80740 | 5 | 1 | 37 | |
| GSE46452 | LY6G6C | 80740 | 1 | 10 | 48 | |
| GSE47630 | LY6G6C | 80740 | 7 | 4 | 29 | |
| GSE54993 | LY6G6C | 80740 | 2 | 1 | 67 | |
| GSE54994 | LY6G6C | 80740 | 11 | 4 | 38 | |
| GSE60625 | LY6G6C | 80740 | 0 | 1 | 10 | |
| GSE74703 | LY6G6C | 80740 | 5 | 0 | 31 | |
| GSE74704 | LY6G6C | 80740 | 2 | 0 | 18 | |
| TCGA | LY6G6C | 80740 | 16 | 16 | 64 |
Total number of gains: 59; Total number of losses: 39; Total Number of normals: 390.
Somatic mutations of LY6G6C:
Generating mutation plots.
Highly correlated genes for LY6G6C:
Showing top 20/756 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LY6G6C | TEX13B | 0.764448 | 3 | 0 | 3 |
| LY6G6C | SH3PXD2A-AS1 | 0.752512 | 4 | 0 | 4 |
| LY6G6C | FAM163B | 0.741386 | 3 | 0 | 3 |
| LY6G6C | SULT2B1 | 0.732395 | 9 | 0 | 8 |
| LY6G6C | RNF222 | 0.731016 | 3 | 0 | 3 |
| LY6G6C | HES5 | 0.722783 | 4 | 0 | 4 |
| LY6G6C | PRSS2 | 0.72107 | 9 | 0 | 8 |
| LY6G6C | NCCRP1 | 0.720854 | 3 | 0 | 3 |
| LY6G6C | RGR | 0.720627 | 4 | 0 | 3 |
| LY6G6C | GLYATL1 | 0.717075 | 3 | 0 | 3 |
| LY6G6C | KCNT1 | 0.716006 | 3 | 0 | 3 |
| LY6G6C | ACER1 | 0.714009 | 7 | 0 | 7 |
| LY6G6C | ACTL6B | 0.713291 | 3 | 0 | 3 |
| LY6G6C | CMTR2 | 0.71187 | 3 | 0 | 3 |
| LY6G6C | DEGS2 | 0.70521 | 7 | 0 | 7 |
| LY6G6C | OTOP3 | 0.70508 | 3 | 0 | 3 |
| LY6G6C | NOTO | 0.703724 | 3 | 0 | 3 |
| LY6G6C | RAET1E | 0.703692 | 7 | 0 | 7 |
| LY6G6C | CES2 | 0.701493 | 9 | 0 | 8 |
| LY6G6C | KPRP | 0.698332 | 4 | 0 | 4 |
For details and further investigation, click here
