| Full name: actin related protein T2 | Alias Symbol: Arp-T2|ARPM2|FLJ25424 | ||
| Type: protein-coding gene | Cytoband: 1p36.32 | ||
| Entrez ID: 140625 | HGNC ID: HGNC:24026 | Ensembl Gene: ENSG00000169717 | OMIM ID: 608535 |
| Drug and gene relationship at DGIdb | |||
Expression of ACTRT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACTRT2 | 140625 | 237360_at | 0.0958 | 0.7771 | |
| GSE26886 | ACTRT2 | 140625 | 237360_at | 0.3346 | 0.0197 | |
| GSE45670 | ACTRT2 | 140625 | 237360_at | 0.1282 | 0.1759 | |
| GSE53622 | ACTRT2 | 140625 | 11053 | -0.0476 | 0.5738 | |
| GSE53624 | ACTRT2 | 140625 | 11053 | -0.1088 | 0.1374 | |
| GSE63941 | ACTRT2 | 140625 | 237360_at | 0.2006 | 0.1728 | |
| GSE77861 | ACTRT2 | 140625 | 237360_at | -0.0632 | 0.7183 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ACTRT2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACTRT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACTRT2 | 140625 | 3 | 6 | 21 | |
| GSE20123 | ACTRT2 | 140625 | 3 | 5 | 22 | |
| GSE43470 | ACTRT2 | 140625 | 3 | 5 | 35 | |
| GSE46452 | ACTRT2 | 140625 | 7 | 1 | 51 | |
| GSE47630 | ACTRT2 | 140625 | 8 | 4 | 28 | |
| GSE54993 | ACTRT2 | 140625 | 3 | 2 | 65 | |
| GSE54994 | ACTRT2 | 140625 | 14 | 3 | 36 | |
| GSE60625 | ACTRT2 | 140625 | 0 | 0 | 11 | |
| GSE74703 | ACTRT2 | 140625 | 3 | 3 | 30 | |
| GSE74704 | ACTRT2 | 140625 | 3 | 0 | 17 | |
| TCGA | ACTRT2 | 140625 | 14 | 20 | 62 |
Total number of gains: 61; Total number of losses: 49; Total Number of normals: 378.
Somatic mutations of ACTRT2:
Generating mutation plots.
Highly correlated genes for ACTRT2:
Showing top 20/77 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACTRT2 | GTPBP10 | 0.688464 | 3 | 0 | 3 |
| ACTRT2 | PRX | 0.667893 | 3 | 0 | 3 |
| ACTRT2 | FFAR1 | 0.661787 | 3 | 0 | 3 |
| ACTRT2 | SCUBE1 | 0.658593 | 4 | 0 | 3 |
| ACTRT2 | SERPINF2 | 0.653739 | 3 | 0 | 3 |
| ACTRT2 | UPK3A | 0.645204 | 3 | 0 | 3 |
| ACTRT2 | FGF17 | 0.64483 | 3 | 0 | 3 |
| ACTRT2 | GJD4 | 0.642531 | 3 | 0 | 3 |
| ACTRT2 | ST8SIA2 | 0.638681 | 4 | 0 | 3 |
| ACTRT2 | GRIN3B | 0.634104 | 3 | 0 | 3 |
| ACTRT2 | PRR7 | 0.632402 | 3 | 0 | 3 |
| ACTRT2 | SEC14L3 | 0.631883 | 3 | 0 | 3 |
| ACTRT2 | ASPHD1 | 0.630751 | 3 | 0 | 3 |
| ACTRT2 | ZNF32-AS3 | 0.629528 | 3 | 0 | 3 |
| ACTRT2 | HOXD9 | 0.611618 | 3 | 0 | 3 |
| ACTRT2 | SPATA45 | 0.60583 | 3 | 0 | 3 |
| ACTRT2 | NEU4 | 0.605371 | 4 | 0 | 3 |
| ACTRT2 | CTBP1-AS | 0.604343 | 3 | 0 | 3 |
| ACTRT2 | KCNC3 | 0.602769 | 4 | 0 | 3 |
| ACTRT2 | JSRP1 | 0.600939 | 4 | 0 | 3 |
For details and further investigation, click here
