| Full name: uroplakin 3A | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 22q13.31 | ||
| Entrez ID: 7380 | HGNC ID: HGNC:12580 | Ensembl Gene: ENSG00000100373 | OMIM ID: 611559 |
| Drug and gene relationship at DGIdb | |||
Expression of UPK3A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UPK3A | 7380 | 206771_at | 0.1262 | 0.5805 | |
| GSE20347 | UPK3A | 7380 | 206771_at | -0.0365 | 0.5893 | |
| GSE23400 | UPK3A | 7380 | 206771_at | -0.0834 | 0.0047 | |
| GSE26886 | UPK3A | 7380 | 206771_at | 0.2936 | 0.0142 | |
| GSE29001 | UPK3A | 7380 | 206771_at | -0.1067 | 0.3368 | |
| GSE38129 | UPK3A | 7380 | 206771_at | -0.1271 | 0.0817 | |
| GSE45670 | UPK3A | 7380 | 206771_at | 0.0891 | 0.3190 | |
| GSE53622 | UPK3A | 7380 | 54358 | -0.2772 | 0.0010 | |
| GSE53624 | UPK3A | 7380 | 54358 | -0.3250 | 0.0003 | |
| GSE63941 | UPK3A | 7380 | 206771_at | 0.1719 | 0.2560 | |
| GSE77861 | UPK3A | 7380 | 206771_at | -0.0472 | 0.7854 | |
| GSE97050 | UPK3A | 7380 | A_24_P348594 | -0.2451 | 0.4119 | |
| TCGA | UPK3A | 7380 | RNAseq | -0.5227 | 0.5885 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by UPK3A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UPK3A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UPK3A | 7380 | 5 | 6 | 19 | |
| GSE20123 | UPK3A | 7380 | 4 | 5 | 21 | |
| GSE43470 | UPK3A | 7380 | 2 | 6 | 35 | |
| GSE46452 | UPK3A | 7380 | 31 | 2 | 26 | |
| GSE47630 | UPK3A | 7380 | 9 | 4 | 27 | |
| GSE54993 | UPK3A | 7380 | 3 | 6 | 61 | |
| GSE54994 | UPK3A | 7380 | 11 | 7 | 35 | |
| GSE60625 | UPK3A | 7380 | 5 | 0 | 6 | |
| GSE74703 | UPK3A | 7380 | 2 | 4 | 30 | |
| GSE74704 | UPK3A | 7380 | 2 | 3 | 15 | |
| TCGA | UPK3A | 7380 | 27 | 15 | 54 |
Total number of gains: 101; Total number of losses: 58; Total Number of normals: 329.
Somatic mutations of UPK3A:
Generating mutation plots.
Highly correlated genes for UPK3A:
Showing top 20/1002 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UPK3A | RLN3 | 0.817264 | 3 | 0 | 3 |
| UPK3A | HSF4 | 0.736726 | 3 | 0 | 3 |
| UPK3A | VMO1 | 0.734728 | 3 | 0 | 3 |
| UPK3A | ZIC1 | 0.728515 | 3 | 0 | 3 |
| UPK3A | C6orf15 | 0.718181 | 3 | 0 | 3 |
| UPK3A | ENGASE | 0.713618 | 3 | 0 | 3 |
| UPK3A | SPATA2L | 0.711873 | 3 | 0 | 3 |
| UPK3A | CHD5 | 0.706407 | 5 | 0 | 5 |
| UPK3A | RASL10B | 0.70619 | 4 | 0 | 3 |
| UPK3A | MGAT5B | 0.70516 | 4 | 0 | 4 |
| UPK3A | MASP2 | 0.704437 | 5 | 0 | 5 |
| UPK3A | CA6 | 0.701854 | 3 | 0 | 3 |
| UPK3A | CLCNKA | 0.700436 | 3 | 0 | 3 |
| UPK3A | GDF7 | 0.69911 | 3 | 0 | 3 |
| UPK3A | MUC3A | 0.698677 | 3 | 0 | 3 |
| UPK3A | IL17B | 0.697926 | 3 | 0 | 3 |
| UPK3A | NPBWR1 | 0.697851 | 3 | 0 | 3 |
| UPK3A | TDGF1 | 0.696271 | 3 | 0 | 3 |
| UPK3A | C16orf71 | 0.685237 | 3 | 0 | 3 |
| UPK3A | CDC42EP2 | 0.682685 | 3 | 0 | 3 |
For details and further investigation, click here
