| Full name: acylphosphatase 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q24.3 | ||
| Entrez ID: 97 | HGNC ID: HGNC:179 | Ensembl Gene: ENSG00000119640 | OMIM ID: 600875 |
| Drug and gene relationship at DGIdb | |||
Expression of ACYP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACYP1 | 97 | 205260_s_at | -0.1337 | 0.8085 | |
| GSE20347 | ACYP1 | 97 | 205260_s_at | 0.5951 | 0.0010 | |
| GSE23400 | ACYP1 | 97 | 205260_s_at | 0.7831 | 0.0000 | |
| GSE26886 | ACYP1 | 97 | 205260_s_at | 1.2888 | 0.0005 | |
| GSE29001 | ACYP1 | 97 | 205260_s_at | 0.7687 | 0.0071 | |
| GSE38129 | ACYP1 | 97 | 205260_s_at | 0.7082 | 0.0000 | |
| GSE45670 | ACYP1 | 97 | 205260_s_at | 0.2626 | 0.1555 | |
| GSE53622 | ACYP1 | 97 | 45662 | 0.9100 | 0.0000 | |
| GSE53624 | ACYP1 | 97 | 45662 | 0.9472 | 0.0000 | |
| GSE63941 | ACYP1 | 97 | 205260_s_at | 1.4650 | 0.0078 | |
| GSE77861 | ACYP1 | 97 | 205260_s_at | 0.6351 | 0.1902 | |
| GSE97050 | ACYP1 | 97 | A_23_P163143 | 0.3182 | 0.2262 | |
| SRP007169 | ACYP1 | 97 | RNAseq | 0.9142 | 0.1372 | |
| SRP008496 | ACYP1 | 97 | RNAseq | 1.3724 | 0.0059 | |
| SRP064894 | ACYP1 | 97 | RNAseq | 0.9972 | 0.0000 | |
| SRP133303 | ACYP1 | 97 | RNAseq | 0.3286 | 0.1097 | |
| SRP159526 | ACYP1 | 97 | RNAseq | 0.8115 | 0.0286 | |
| SRP193095 | ACYP1 | 97 | RNAseq | 0.5194 | 0.0002 | |
| SRP219564 | ACYP1 | 97 | RNAseq | 0.3182 | 0.2646 | |
| TCGA | ACYP1 | 97 | RNAseq | 0.6894 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by ACYP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACYP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACYP1 | 97 | 8 | 3 | 19 | |
| GSE20123 | ACYP1 | 97 | 8 | 3 | 19 | |
| GSE43470 | ACYP1 | 97 | 8 | 3 | 32 | |
| GSE46452 | ACYP1 | 97 | 16 | 3 | 40 | |
| GSE47630 | ACYP1 | 97 | 11 | 8 | 21 | |
| GSE54993 | ACYP1 | 97 | 3 | 8 | 59 | |
| GSE54994 | ACYP1 | 97 | 19 | 4 | 30 | |
| GSE60625 | ACYP1 | 97 | 0 | 2 | 9 | |
| GSE74703 | ACYP1 | 97 | 7 | 3 | 26 | |
| GSE74704 | ACYP1 | 97 | 3 | 3 | 14 | |
| TCGA | ACYP1 | 97 | 33 | 16 | 47 |
Total number of gains: 116; Total number of losses: 56; Total Number of normals: 316.
Somatic mutations of ACYP1:
Generating mutation plots.
Highly correlated genes for ACYP1:
Showing top 20/1239 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACYP1 | HERPUD2 | 0.755408 | 3 | 0 | 3 |
| ACYP1 | ZNF707 | 0.75324 | 3 | 0 | 3 |
| ACYP1 | LRRC58 | 0.752496 | 3 | 0 | 3 |
| ACYP1 | ACY1 | 0.748321 | 3 | 0 | 3 |
| ACYP1 | WDR54 | 0.748112 | 6 | 0 | 6 |
| ACYP1 | DECR2 | 0.740526 | 3 | 0 | 3 |
| ACYP1 | CPT1A | 0.739613 | 4 | 0 | 4 |
| ACYP1 | PRKAB2 | 0.738333 | 3 | 0 | 3 |
| ACYP1 | AFAP1L2 | 0.737278 | 4 | 0 | 3 |
| ACYP1 | DQX1 | 0.728971 | 3 | 0 | 3 |
| ACYP1 | NSMCE4A | 0.723114 | 3 | 0 | 3 |
| ACYP1 | KRTCAP2 | 0.722329 | 4 | 0 | 4 |
| ACYP1 | MYOF | 0.720481 | 5 | 0 | 4 |
| ACYP1 | TEP1 | 0.718217 | 3 | 0 | 3 |
| ACYP1 | MTHFD1 | 0.71497 | 12 | 0 | 11 |
| ACYP1 | NEIL2 | 0.711864 | 4 | 0 | 4 |
| ACYP1 | ROMO1 | 0.709957 | 3 | 0 | 3 |
| ACYP1 | ZIC5 | 0.707183 | 4 | 0 | 3 |
| ACYP1 | SCNM1 | 0.704 | 3 | 0 | 3 |
| ACYP1 | CMTM4 | 0.699631 | 3 | 0 | 3 |
For details and further investigation, click here
