| Full name: telomerase associated protein 1 | Alias Symbol: TP1|TLP1|VAULT2|p240|TROVE1 | ||
| Type: protein-coding gene | Cytoband: 14q11.2 | ||
| Entrez ID: 7011 | HGNC ID: HGNC:11726 | Ensembl Gene: ENSG00000129566 | OMIM ID: 601686 |
| Drug and gene relationship at DGIdb | |||
Expression of TEP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TEP1 | 7011 | 228670_at | 0.2134 | 0.8105 | |
| GSE20347 | TEP1 | 7011 | 205727_at | 0.0641 | 0.7500 | |
| GSE23400 | TEP1 | 7011 | 205727_at | -0.0553 | 0.2518 | |
| GSE26886 | TEP1 | 7011 | 228670_at | 0.9039 | 0.0045 | |
| GSE29001 | TEP1 | 7011 | 205727_at | 0.1423 | 0.2902 | |
| GSE38129 | TEP1 | 7011 | 205727_at | 0.1060 | 0.6697 | |
| GSE45670 | TEP1 | 7011 | 228670_at | 0.1873 | 0.4224 | |
| GSE53622 | TEP1 | 7011 | 30162 | 0.0456 | 0.6230 | |
| GSE53624 | TEP1 | 7011 | 30162 | 0.0416 | 0.5732 | |
| GSE63941 | TEP1 | 7011 | 228670_at | -0.7768 | 0.1741 | |
| GSE77861 | TEP1 | 7011 | 228670_at | 0.2908 | 0.1646 | |
| GSE97050 | TEP1 | 7011 | A_23_P65481 | 0.4276 | 0.1399 | |
| SRP007169 | TEP1 | 7011 | RNAseq | 1.4789 | 0.0181 | |
| SRP008496 | TEP1 | 7011 | RNAseq | 1.2887 | 0.0008 | |
| SRP064894 | TEP1 | 7011 | RNAseq | 0.8547 | 0.0000 | |
| SRP133303 | TEP1 | 7011 | RNAseq | 0.2286 | 0.2063 | |
| SRP159526 | TEP1 | 7011 | RNAseq | -0.2413 | 0.3721 | |
| SRP193095 | TEP1 | 7011 | RNAseq | 0.0488 | 0.8344 | |
| SRP219564 | TEP1 | 7011 | RNAseq | 0.2887 | 0.2900 | |
| TCGA | TEP1 | 7011 | RNAseq | -0.1405 | 0.0207 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by TEP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TEP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TEP1 | 7011 | 11 | 3 | 16 | |
| GSE20123 | TEP1 | 7011 | 9 | 3 | 18 | |
| GSE43470 | TEP1 | 7011 | 7 | 1 | 35 | |
| GSE46452 | TEP1 | 7011 | 19 | 2 | 38 | |
| GSE47630 | TEP1 | 7011 | 10 | 10 | 20 | |
| GSE54993 | TEP1 | 7011 | 3 | 11 | 56 | |
| GSE54994 | TEP1 | 7011 | 18 | 5 | 30 | |
| GSE60625 | TEP1 | 7011 | 0 | 2 | 9 | |
| GSE74703 | TEP1 | 7011 | 6 | 1 | 29 | |
| GSE74704 | TEP1 | 7011 | 4 | 2 | 14 | |
| TCGA | TEP1 | 7011 | 28 | 16 | 52 |
Total number of gains: 115; Total number of losses: 56; Total Number of normals: 317.
Somatic mutations of TEP1:
Generating mutation plots.
Highly correlated genes for TEP1:
Showing top 20/327 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TEP1 | ORC2 | 0.774327 | 3 | 0 | 3 |
| TEP1 | ZBED6 | 0.735943 | 3 | 0 | 3 |
| TEP1 | DDX55 | 0.731256 | 4 | 0 | 3 |
| TEP1 | PKNOX1 | 0.725692 | 4 | 0 | 4 |
| TEP1 | ACYP1 | 0.718217 | 3 | 0 | 3 |
| TEP1 | CHD1L | 0.715373 | 4 | 0 | 4 |
| TEP1 | PTPN4 | 0.712884 | 3 | 0 | 3 |
| TEP1 | PSMA7 | 0.707202 | 3 | 0 | 3 |
| TEP1 | SKIL | 0.704455 | 3 | 0 | 3 |
| TEP1 | SLC30A7 | 0.699418 | 3 | 0 | 3 |
| TEP1 | FASTKD1 | 0.696696 | 3 | 0 | 3 |
| TEP1 | SCARB1 | 0.694794 | 3 | 0 | 3 |
| TEP1 | KIF3B | 0.6944 | 3 | 0 | 3 |
| TEP1 | ZNF623 | 0.691458 | 4 | 0 | 4 |
| TEP1 | NCAPD3 | 0.691358 | 3 | 0 | 3 |
| TEP1 | MSTO1 | 0.690866 | 3 | 0 | 3 |
| TEP1 | FASTKD3 | 0.68989 | 4 | 0 | 3 |
| TEP1 | PDK1 | 0.689458 | 4 | 0 | 4 |
| TEP1 | SRA1 | 0.683516 | 3 | 0 | 3 |
| TEP1 | NEK8 | 0.682625 | 3 | 0 | 3 |
For details and further investigation, click here
