| Full name: ADP-ribosylhydrolase like 2 | Alias Symbol: ARH3|FLJ20446 | ||
| Type: protein-coding gene | Cytoband: 1p34.3 | ||
| Entrez ID: 54936 | HGNC ID: HGNC:21304 | Ensembl Gene: ENSG00000116863 | OMIM ID: 610624 |
| Drug and gene relationship at DGIdb | |||
Expression of ADPRHL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADPRHL2 | 54936 | 223097_at | 0.0846 | 0.9104 | |
| GSE26886 | ADPRHL2 | 54936 | 223097_at | -0.3131 | 0.2102 | |
| GSE45670 | ADPRHL2 | 54936 | 223097_at | 0.0791 | 0.6852 | |
| GSE53622 | ADPRHL2 | 54936 | 89508 | -0.1205 | 0.0600 | |
| GSE53624 | ADPRHL2 | 54936 | 89508 | -0.2742 | 0.0000 | |
| GSE63941 | ADPRHL2 | 54936 | 223097_at | -0.6301 | 0.1165 | |
| GSE77861 | ADPRHL2 | 54936 | 223097_at | -0.2861 | 0.1945 | |
| GSE97050 | ADPRHL2 | 54936 | A_23_P34568 | 0.1593 | 0.5619 | |
| SRP007169 | ADPRHL2 | 54936 | RNAseq | -0.6106 | 0.0970 | |
| SRP008496 | ADPRHL2 | 54936 | RNAseq | -0.7482 | 0.0016 | |
| SRP064894 | ADPRHL2 | 54936 | RNAseq | 0.2054 | 0.3589 | |
| SRP133303 | ADPRHL2 | 54936 | RNAseq | -0.0711 | 0.6578 | |
| SRP159526 | ADPRHL2 | 54936 | RNAseq | -0.4129 | 0.1307 | |
| SRP193095 | ADPRHL2 | 54936 | RNAseq | -0.1463 | 0.2134 | |
| SRP219564 | ADPRHL2 | 54936 | RNAseq | -0.5060 | 0.0212 | |
| TCGA | ADPRHL2 | 54936 | RNAseq | 0.0906 | 0.1263 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ADPRHL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ADPRHL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADPRHL2 | 54936 | 3 | 5 | 22 | |
| GSE20123 | ADPRHL2 | 54936 | 3 | 4 | 23 | |
| GSE43470 | ADPRHL2 | 54936 | 7 | 2 | 34 | |
| GSE46452 | ADPRHL2 | 54936 | 4 | 1 | 54 | |
| GSE47630 | ADPRHL2 | 54936 | 8 | 3 | 29 | |
| GSE54993 | ADPRHL2 | 54936 | 1 | 1 | 68 | |
| GSE54994 | ADPRHL2 | 54936 | 11 | 2 | 40 | |
| GSE60625 | ADPRHL2 | 54936 | 0 | 0 | 11 | |
| GSE74703 | ADPRHL2 | 54936 | 6 | 1 | 29 | |
| GSE74704 | ADPRHL2 | 54936 | 2 | 0 | 18 | |
| TCGA | ADPRHL2 | 54936 | 11 | 19 | 66 |
Total number of gains: 56; Total number of losses: 38; Total Number of normals: 394.
Somatic mutations of ADPRHL2:
Generating mutation plots.
Highly correlated genes for ADPRHL2:
Showing top 20/99 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADPRHL2 | ARMC5 | 0.68987 | 3 | 0 | 3 |
| ADPRHL2 | ADAMTS7 | 0.68805 | 3 | 0 | 3 |
| ADPRHL2 | LAMTOR2 | 0.679555 | 3 | 0 | 3 |
| ADPRHL2 | CNDP2 | 0.65865 | 4 | 0 | 4 |
| ADPRHL2 | TERT | 0.652014 | 3 | 0 | 3 |
| ADPRHL2 | ZMYND8 | 0.649769 | 3 | 0 | 3 |
| ADPRHL2 | AIRE | 0.649385 | 3 | 0 | 3 |
| ADPRHL2 | LRRC45 | 0.640903 | 3 | 0 | 3 |
| ADPRHL2 | TULP1 | 0.640502 | 4 | 0 | 3 |
| ADPRHL2 | GPR39 | 0.639129 | 3 | 0 | 3 |
| ADPRHL2 | CCDC157 | 0.637226 | 3 | 0 | 3 |
| ADPRHL2 | ATP6AP2 | 0.63381 | 4 | 0 | 3 |
| ADPRHL2 | CDK5R2 | 0.631333 | 3 | 0 | 3 |
| ADPRHL2 | ELOVL1 | 0.630036 | 3 | 0 | 3 |
| ADPRHL2 | LYPLA2 | 0.626826 | 5 | 0 | 4 |
| ADPRHL2 | B3GNTL1 | 0.625459 | 3 | 0 | 3 |
| ADPRHL2 | SLC10A6 | 0.624736 | 3 | 0 | 3 |
| ADPRHL2 | ANKFN1 | 0.624551 | 3 | 0 | 3 |
| ADPRHL2 | BTF3L4 | 0.623149 | 4 | 0 | 3 |
| ADPRHL2 | ABCD3 | 0.617869 | 4 | 0 | 3 |
For details and further investigation, click here
