| Full name: solute carrier family 10 member 6 | Alias Symbol: SOAT | ||
| Type: protein-coding gene | Cytoband: 4q21.3 | ||
| Entrez ID: 345274 | HGNC ID: HGNC:30603 | Ensembl Gene: ENSG00000145283 | OMIM ID: 613366 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC10A6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | SLC10A6 | 345274 | 51224 | -1.4921 | 0.0000 | |
| GSE53624 | SLC10A6 | 345274 | 51224 | -1.3604 | 0.0000 | |
| GSE97050 | SLC10A6 | 345274 | A_33_P3212102 | 0.0837 | 0.8278 | |
| SRP007169 | SLC10A6 | 345274 | RNAseq | -2.5764 | 0.0008 | |
| SRP008496 | SLC10A6 | 345274 | RNAseq | -2.9179 | 0.0000 | |
| SRP064894 | SLC10A6 | 345274 | RNAseq | -1.6519 | 0.0005 | |
| SRP133303 | SLC10A6 | 345274 | RNAseq | -1.6116 | 0.0006 | |
| SRP159526 | SLC10A6 | 345274 | RNAseq | -2.2344 | 0.0101 | |
| SRP219564 | SLC10A6 | 345274 | RNAseq | -1.7266 | 0.0291 | |
| TCGA | SLC10A6 | 345274 | RNAseq | 0.5622 | 0.1083 |
Upregulated datasets: 0; Downregulated datasets: 8.
Survival by SLC10A6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC10A6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC10A6 | 345274 | 3 | 12 | 15 | |
| GSE20123 | SLC10A6 | 345274 | 3 | 12 | 15 | |
| GSE43470 | SLC10A6 | 345274 | 0 | 13 | 30 | |
| GSE46452 | SLC10A6 | 345274 | 2 | 35 | 22 | |
| GSE47630 | SLC10A6 | 345274 | 0 | 20 | 20 | |
| GSE54993 | SLC10A6 | 345274 | 8 | 0 | 62 | |
| GSE54994 | SLC10A6 | 345274 | 1 | 10 | 42 | |
| GSE60625 | SLC10A6 | 345274 | 0 | 0 | 11 | |
| GSE74703 | SLC10A6 | 345274 | 0 | 11 | 25 | |
| GSE74704 | SLC10A6 | 345274 | 2 | 7 | 11 | |
| TCGA | SLC10A6 | 345274 | 12 | 35 | 49 |
Total number of gains: 31; Total number of losses: 155; Total Number of normals: 302.
Somatic mutations of SLC10A6:
Generating mutation plots.
Highly correlated genes for SLC10A6:
Showing top 20/139 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC10A6 | KLK2 | 0.754287 | 3 | 0 | 3 |
| SLC10A6 | DCD | 0.736024 | 3 | 0 | 3 |
| SLC10A6 | HMGB4 | 0.73216 | 3 | 0 | 3 |
| SLC10A6 | NHLRC4 | 0.72729 | 3 | 0 | 3 |
| SLC10A6 | CLEC12B | 0.724877 | 3 | 0 | 3 |
| SLC10A6 | DSC2 | 0.71199 | 3 | 0 | 3 |
| SLC10A6 | UPP1 | 0.709095 | 3 | 0 | 3 |
| SLC10A6 | ATP2B3 | 0.705983 | 3 | 0 | 3 |
| SLC10A6 | RNF222 | 0.702299 | 3 | 0 | 3 |
| SLC10A6 | LYPD3 | 0.696115 | 3 | 0 | 3 |
| SLC10A6 | C3orf20 | 0.696051 | 3 | 0 | 3 |
| SLC10A6 | HES5 | 0.69182 | 3 | 0 | 3 |
| SLC10A6 | ULBP2 | 0.691128 | 3 | 0 | 3 |
| SLC10A6 | BAIAP2 | 0.688213 | 3 | 0 | 3 |
| SLC10A6 | KRT6C | 0.68814 | 3 | 0 | 3 |
| SLC10A6 | SBSN | 0.685761 | 3 | 0 | 3 |
| SLC10A6 | TTC39A | 0.681674 | 3 | 0 | 3 |
| SLC10A6 | NOTO | 0.681244 | 3 | 0 | 3 |
| SLC10A6 | SDCBP2 | 0.680781 | 3 | 0 | 3 |
| SLC10A6 | ETHE1 | 0.679051 | 3 | 0 | 3 |
For details and further investigation, click here
