AGFG1

 

Full name: ArfGAP with FG repeats 1 Alias Symbol: RIP|RAB
Type: protein-coding gene Cytoband: 2q36.3
Entrez ID: 3267 HGNC ID: HGNC:5175 Ensembl Gene: ENSG00000173744 OMIM ID: 600862
Drug and gene relationship at DGIdb

 

Expression of AGFG1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 AGFG1 3267 218091_at 0.0365 0.9437
GSE20347 AGFG1 3267 218091_at -0.0054 0.9748
GSE23400 AGFG1 3267 218091_at 0.0403 0.4795
GSE26886 AGFG1 3267 218092_s_at -0.4365 0.0863
GSE29001 AGFG1 3267 218091_at 0.0230 0.9148
GSE38129 AGFG1 3267 218091_at 0.0482 0.7022
GSE45670 AGFG1 3267 218092_s_at 0.6778 0.0002
GSE53622 AGFG1 3267 15296 0.3128 0.0000
GSE53624 AGFG1 3267 15296 0.0221 0.7681
GSE63941 AGFG1 3267 218092_s_at -0.0745 0.8969
GSE77861 AGFG1 3267 218092_s_at 0.0100 0.9873
GSE97050 AGFG1 3267 A_33_P3238993 0.7292 0.1646
SRP007169 AGFG1 3267 RNAseq 0.1089 0.8121
SRP008496 AGFG1 3267 RNAseq 0.2674 0.3454
SRP064894 AGFG1 3267 RNAseq 0.0474 0.7877
SRP133303 AGFG1 3267 RNAseq 0.6820 0.0010
SRP159526 AGFG1 3267 RNAseq -0.0413 0.8587
SRP193095 AGFG1 3267 RNAseq 0.1708 0.2166
SRP219564 AGFG1 3267 RNAseq -0.3521 0.2209
TCGA AGFG1 3267 RNAseq 0.0780 0.0985

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by AGFG1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of AGFG1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 AGFG1 3267 2 12 16
GSE20123 AGFG1 3267 2 12 16
GSE43470 AGFG1 3267 0 7 36
GSE46452 AGFG1 3267 0 5 54
GSE47630 AGFG1 3267 4 5 31
GSE54993 AGFG1 3267 1 2 67
GSE54994 AGFG1 3267 6 11 36
GSE60625 AGFG1 3267 0 3 8
GSE74703 AGFG1 3267 0 6 30
GSE74704 AGFG1 3267 2 6 12
TCGA AGFG1 3267 13 26 57

Total number of gains: 30; Total number of losses: 95; Total Number of normals: 363.  


 

Somatic mutations of AGFG1:

 

Generating mutation plots.

 

Highly correlated genes for AGFG1:

 

Showing top 20/216 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
AGFG1STAMBP0.787052303
AGFG1SP1100.777987303
AGFG1PPP4R20.725662303
AGFG1ESR20.723623303
AGFG1TMEM190.720738303
AGFG1MTIF20.716928303
AGFG1SUPT4H10.69974303
AGFG1POLR2C0.696486303
AGFG1CD2BP20.695708303
AGFG1TRUB10.694462303
AGFG1KCMF10.694161303
AGFG1HERPUD20.694066303
AGFG1CCDC85C0.692015303
AGFG1MEF2A0.69148303
AGFG1ACSS20.689563303
AGFG1TUFM0.688658303
AGFG1ARPC20.682553303
AGFG1CYLD0.679731403
AGFG1ZNF6680.675283303
AGFG1SEC61G0.673286403

For details and further investigation, click here