| Full name: SPT4 homolog, DSIF elongation factor subunit | Alias Symbol: SPT4H|Spt4|Supt4a | ||
| Type: protein-coding gene | Cytoband: 17q22 | ||
| Entrez ID: 6827 | HGNC ID: HGNC:11467 | Ensembl Gene: ENSG00000213246 | OMIM ID: 603555 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SUPT4H1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SUPT4H1 | 6827 | 201483_s_at | -0.0640 | 0.8494 | |
| GSE20347 | SUPT4H1 | 6827 | 201483_s_at | -0.1953 | 0.3990 | |
| GSE23400 | SUPT4H1 | 6827 | 201483_s_at | 0.0990 | 0.0704 | |
| GSE26886 | SUPT4H1 | 6827 | 201484_at | -0.9191 | 0.0000 | |
| GSE29001 | SUPT4H1 | 6827 | 201484_at | -0.0122 | 0.9677 | |
| GSE38129 | SUPT4H1 | 6827 | 201483_s_at | 0.1041 | 0.6290 | |
| GSE45670 | SUPT4H1 | 6827 | 201483_s_at | -0.0027 | 0.9857 | |
| GSE53622 | SUPT4H1 | 6827 | 5576 | -0.2107 | 0.0000 | |
| GSE53624 | SUPT4H1 | 6827 | 5576 | -0.1240 | 0.0062 | |
| GSE63941 | SUPT4H1 | 6827 | 201483_s_at | 0.5456 | 0.0348 | |
| GSE77861 | SUPT4H1 | 6827 | 201483_s_at | 0.1698 | 0.5881 | |
| GSE97050 | SUPT4H1 | 6827 | A_23_P163942 | -0.0197 | 0.9314 | |
| SRP007169 | SUPT4H1 | 6827 | RNAseq | -0.9278 | 0.0074 | |
| SRP008496 | SUPT4H1 | 6827 | RNAseq | -0.7557 | 0.0000 | |
| SRP064894 | SUPT4H1 | 6827 | RNAseq | -0.0294 | 0.8839 | |
| SRP133303 | SUPT4H1 | 6827 | RNAseq | 0.1661 | 0.2315 | |
| SRP159526 | SUPT4H1 | 6827 | RNAseq | 0.0082 | 0.9586 | |
| SRP193095 | SUPT4H1 | 6827 | RNAseq | -0.3710 | 0.0004 | |
| SRP219564 | SUPT4H1 | 6827 | RNAseq | -0.1487 | 0.5319 | |
| TCGA | SUPT4H1 | 6827 | RNAseq | 0.0437 | 0.3671 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SUPT4H1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SUPT4H1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SUPT4H1 | 6827 | 5 | 1 | 24 | |
| GSE20123 | SUPT4H1 | 6827 | 5 | 1 | 24 | |
| GSE43470 | SUPT4H1 | 6827 | 3 | 0 | 40 | |
| GSE46452 | SUPT4H1 | 6827 | 32 | 0 | 27 | |
| GSE47630 | SUPT4H1 | 6827 | 7 | 1 | 32 | |
| GSE54993 | SUPT4H1 | 6827 | 2 | 5 | 63 | |
| GSE54994 | SUPT4H1 | 6827 | 8 | 6 | 39 | |
| GSE60625 | SUPT4H1 | 6827 | 4 | 0 | 7 | |
| GSE74703 | SUPT4H1 | 6827 | 3 | 0 | 33 | |
| GSE74704 | SUPT4H1 | 6827 | 4 | 1 | 15 | |
| TCGA | SUPT4H1 | 6827 | 27 | 8 | 61 |
Total number of gains: 100; Total number of losses: 23; Total Number of normals: 365.
Somatic mutations of SUPT4H1:
Generating mutation plots.
Highly correlated genes for SUPT4H1:
Showing top 20/395 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SUPT4H1 | FYTTD1 | 0.799917 | 3 | 0 | 3 |
| SUPT4H1 | HCCS | 0.783961 | 3 | 0 | 3 |
| SUPT4H1 | NAA35 | 0.762251 | 3 | 0 | 3 |
| SUPT4H1 | CPT2 | 0.752769 | 3 | 0 | 3 |
| SUPT4H1 | KIAA0355 | 0.748776 | 3 | 0 | 3 |
| SUPT4H1 | ATP6V0D1 | 0.744236 | 5 | 0 | 5 |
| SUPT4H1 | IST1 | 0.734411 | 4 | 0 | 4 |
| SUPT4H1 | BRK1 | 0.732955 | 4 | 0 | 3 |
| SUPT4H1 | BCKDK | 0.732839 | 4 | 0 | 4 |
| SUPT4H1 | LRP10 | 0.731231 | 3 | 0 | 3 |
| SUPT4H1 | ECI2 | 0.727863 | 4 | 0 | 4 |
| SUPT4H1 | ANKRD13A | 0.713896 | 4 | 0 | 3 |
| SUPT4H1 | UBR4 | 0.713736 | 3 | 0 | 3 |
| SUPT4H1 | MRPL39 | 0.710416 | 3 | 0 | 3 |
| SUPT4H1 | TRIM6 | 0.71027 | 3 | 0 | 3 |
| SUPT4H1 | TJP1 | 0.708946 | 3 | 0 | 3 |
| SUPT4H1 | DHX35 | 0.708322 | 3 | 0 | 3 |
| SUPT4H1 | KAT7 | 0.707068 | 4 | 0 | 3 |
| SUPT4H1 | SNX4 | 0.70467 | 4 | 0 | 4 |
| SUPT4H1 | MRPL10 | 0.703825 | 5 | 0 | 4 |
For details and further investigation, click here
