| Full name: Tu translation elongation factor, mitochondrial | Alias Symbol: EFTu|EF-TuMT|EFTU | ||
| Type: protein-coding gene | Cytoband: 16p11.2 | ||
| Entrez ID: 7284 | HGNC ID: HGNC:12420 | Ensembl Gene: ENSG00000178952 | OMIM ID: 602389 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of TUFM:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TUFM | 7284 | 201113_at | 0.3856 | 0.5167 | |
| GSE20347 | TUFM | 7284 | 201113_at | 0.1160 | 0.4148 | |
| GSE23400 | TUFM | 7284 | 201113_at | 0.3060 | 0.0000 | |
| GSE26886 | TUFM | 7284 | 201113_at | -0.2296 | 0.1316 | |
| GSE29001 | TUFM | 7284 | 201113_at | 0.0785 | 0.8695 | |
| GSE38129 | TUFM | 7284 | 201113_at | 0.2906 | 0.0088 | |
| GSE45670 | TUFM | 7284 | 201113_at | 0.3029 | 0.0326 | |
| GSE63941 | TUFM | 7284 | 201113_at | 0.4973 | 0.1175 | |
| GSE77861 | TUFM | 7284 | 201113_at | 0.2621 | 0.3421 | |
| GSE97050 | TUFM | 7284 | A_23_P9582 | 0.4076 | 0.1934 | |
| SRP007169 | TUFM | 7284 | RNAseq | 0.5987 | 0.1855 | |
| SRP008496 | TUFM | 7284 | RNAseq | 0.3974 | 0.1829 | |
| SRP064894 | TUFM | 7284 | RNAseq | 0.0722 | 0.7242 | |
| SRP133303 | TUFM | 7284 | RNAseq | 0.3615 | 0.0777 | |
| SRP159526 | TUFM | 7284 | RNAseq | 0.0405 | 0.8064 | |
| SRP193095 | TUFM | 7284 | RNAseq | -0.0181 | 0.8667 | |
| SRP219564 | TUFM | 7284 | RNAseq | 0.2919 | 0.3525 | |
| TCGA | TUFM | 7284 | RNAseq | -0.0090 | 0.8438 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TUFM expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of TUFM:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TUFM | 7284 | 5 | 5 | 20 | |
| GSE20123 | TUFM | 7284 | 5 | 4 | 21 | |
| GSE43470 | TUFM | 7284 | 3 | 3 | 37 | |
| GSE46452 | TUFM | 7284 | 38 | 1 | 20 | |
| GSE47630 | TUFM | 7284 | 11 | 7 | 22 | |
| GSE54993 | TUFM | 7284 | 3 | 5 | 62 | |
| GSE54994 | TUFM | 7284 | 5 | 9 | 39 | |
| GSE60625 | TUFM | 7284 | 4 | 0 | 7 | |
| GSE74703 | TUFM | 7284 | 3 | 2 | 31 | |
| GSE74704 | TUFM | 7284 | 3 | 2 | 15 | |
| TCGA | TUFM | 7284 | 20 | 12 | 64 |
Total number of gains: 100; Total number of losses: 50; Total Number of normals: 338.
Somatic mutations of TUFM:
Generating mutation plots.
Highly correlated genes for TUFM:
Showing top 20/851 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TUFM | UQCR10 | 0.78084 | 3 | 0 | 3 |
| TUFM | MRPL51 | 0.776983 | 3 | 0 | 3 |
| TUFM | MRPS11 | 0.764808 | 3 | 0 | 3 |
| TUFM | HMG20A | 0.764628 | 3 | 0 | 3 |
| TUFM | TRAP1 | 0.75183 | 10 | 0 | 10 |
| TUFM | POLDIP3 | 0.748433 | 3 | 0 | 3 |
| TUFM | ZNF689 | 0.73811 | 4 | 0 | 4 |
| TUFM | GSPT1 | 0.737649 | 8 | 0 | 8 |
| TUFM | SUFU | 0.733521 | 3 | 0 | 3 |
| TUFM | CHCHD1 | 0.731797 | 3 | 0 | 3 |
| TUFM | HCCS | 0.729603 | 3 | 0 | 3 |
| TUFM | NMRAL1 | 0.723429 | 3 | 0 | 3 |
| TUFM | UCKL1 | 0.723372 | 3 | 0 | 3 |
| TUFM | SPNS1 | 0.723223 | 5 | 0 | 4 |
| TUFM | S1PR5 | 0.721519 | 3 | 0 | 3 |
| TUFM | DEXI | 0.719049 | 5 | 0 | 5 |
| TUFM | TXNL4A | 0.718557 | 3 | 0 | 3 |
| TUFM | TCHP | 0.717577 | 4 | 0 | 4 |
| TUFM | ID1 | 0.716889 | 3 | 0 | 3 |
| TUFM | TRADD | 0.716157 | 3 | 0 | 3 |
For details and further investigation, click here
