| Full name: Bet1 golgi vesicular membrane trafficking protein | Alias Symbol: hbet1 | ||
| Type: protein-coding gene | Cytoband: 7q21.3 | ||
| Entrez ID: 10282 | HGNC ID: HGNC:14562 | Ensembl Gene: ENSG00000105829 | OMIM ID: 605456 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of BET1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BET1 | 10282 | 202710_at | 0.3949 | 0.4519 | |
| GSE20347 | BET1 | 10282 | 202710_at | 0.4133 | 0.0413 | |
| GSE23400 | BET1 | 10282 | 202710_at | 0.5123 | 0.0000 | |
| GSE26886 | BET1 | 10282 | 202710_at | -0.2131 | 0.4198 | |
| GSE29001 | BET1 | 10282 | 202710_at | 0.6753 | 0.0057 | |
| GSE38129 | BET1 | 10282 | 202710_at | 0.5068 | 0.0002 | |
| GSE45670 | BET1 | 10282 | 202710_at | 0.4994 | 0.0067 | |
| GSE53622 | BET1 | 10282 | 75248 | 0.4418 | 0.0000 | |
| GSE53624 | BET1 | 10282 | 75248 | 0.4667 | 0.0000 | |
| GSE63941 | BET1 | 10282 | 202710_at | -0.8041 | 0.0673 | |
| GSE77861 | BET1 | 10282 | 202710_at | 0.3073 | 0.1927 | |
| GSE97050 | BET1 | 10282 | A_24_P269432 | 0.2743 | 0.3240 | |
| SRP007169 | BET1 | 10282 | RNAseq | 0.0217 | 0.9531 | |
| SRP008496 | BET1 | 10282 | RNAseq | 0.0889 | 0.8181 | |
| SRP064894 | BET1 | 10282 | RNAseq | 0.4046 | 0.0072 | |
| SRP133303 | BET1 | 10282 | RNAseq | 0.6230 | 0.0001 | |
| SRP159526 | BET1 | 10282 | RNAseq | -0.0013 | 0.9953 | |
| SRP193095 | BET1 | 10282 | RNAseq | 0.1436 | 0.2993 | |
| SRP219564 | BET1 | 10282 | RNAseq | 0.5388 | 0.0376 | |
| TCGA | BET1 | 10282 | RNAseq | 0.0800 | 0.2764 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by BET1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BET1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BET1 | 10282 | 13 | 0 | 17 | |
| GSE20123 | BET1 | 10282 | 13 | 0 | 17 | |
| GSE43470 | BET1 | 10282 | 7 | 3 | 33 | |
| GSE46452 | BET1 | 10282 | 12 | 0 | 47 | |
| GSE47630 | BET1 | 10282 | 9 | 2 | 29 | |
| GSE54993 | BET1 | 10282 | 1 | 9 | 60 | |
| GSE54994 | BET1 | 10282 | 16 | 2 | 35 | |
| GSE60625 | BET1 | 10282 | 0 | 5 | 6 | |
| GSE74703 | BET1 | 10282 | 6 | 2 | 28 | |
| GSE74704 | BET1 | 10282 | 9 | 0 | 11 | |
| TCGA | BET1 | 10282 | 56 | 4 | 36 |
Total number of gains: 142; Total number of losses: 27; Total Number of normals: 319.
Somatic mutations of BET1:
Generating mutation plots.
Highly correlated genes for BET1:
Showing top 20/1047 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BET1 | ZNF578 | 0.76985 | 3 | 0 | 3 |
| BET1 | TMED2 | 0.734224 | 5 | 0 | 5 |
| BET1 | INTS10 | 0.726775 | 4 | 0 | 3 |
| BET1 | KIAA0586 | 0.704647 | 3 | 0 | 3 |
| BET1 | RSBN1L | 0.703849 | 4 | 0 | 3 |
| BET1 | ARMC10 | 0.703093 | 5 | 0 | 4 |
| BET1 | RRM2B | 0.703044 | 4 | 0 | 4 |
| BET1 | USP42 | 0.701547 | 4 | 0 | 3 |
| BET1 | ANKRD40 | 0.698385 | 4 | 0 | 4 |
| BET1 | CEP41 | 0.688046 | 4 | 0 | 3 |
| BET1 | WDR77 | 0.687735 | 3 | 0 | 3 |
| BET1 | CWF19L1 | 0.687542 | 4 | 0 | 3 |
| BET1 | MCPH1 | 0.686489 | 4 | 0 | 3 |
| BET1 | DEXI | 0.685586 | 4 | 0 | 4 |
| BET1 | AZIN1 | 0.68304 | 5 | 0 | 5 |
| BET1 | FBXW2 | 0.681158 | 4 | 0 | 3 |
| BET1 | CHM | 0.677848 | 3 | 0 | 3 |
| BET1 | CERS5 | 0.677329 | 3 | 0 | 3 |
| BET1 | DBF4 | 0.67701 | 10 | 0 | 9 |
| BET1 | GNG11 | 0.675084 | 3 | 0 | 3 |
For details and further investigation, click here
