| Full name: PLAG1 like zinc finger 2 | Alias Symbol: ZNF900 | ||
| Type: protein-coding gene | Cytoband: 20q11.21 | ||
| Entrez ID: 5326 | HGNC ID: HGNC:9047 | Ensembl Gene: ENSG00000126003 | OMIM ID: 604866 |
| Drug and gene relationship at DGIdb | |||
Expression of PLAGL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PLAGL2 | 5326 | 202925_s_at | 1.2461 | 0.0147 | |
| GSE20347 | PLAGL2 | 5326 | 202925_s_at | 0.2984 | 0.0136 | |
| GSE23400 | PLAGL2 | 5326 | 202924_s_at | -0.2796 | 0.0000 | |
| GSE26886 | PLAGL2 | 5326 | 202925_s_at | 0.4014 | 0.0284 | |
| GSE29001 | PLAGL2 | 5326 | 202925_s_at | 0.2021 | 0.3003 | |
| GSE38129 | PLAGL2 | 5326 | 202925_s_at | 0.4476 | 0.0008 | |
| GSE45670 | PLAGL2 | 5326 | 202925_s_at | 0.2721 | 0.1024 | |
| GSE53622 | PLAGL2 | 5326 | 38948 | 0.0592 | 0.5814 | |
| GSE53624 | PLAGL2 | 5326 | 38948 | 0.0877 | 0.2695 | |
| GSE63941 | PLAGL2 | 5326 | 202925_s_at | 1.7700 | 0.0030 | |
| GSE77861 | PLAGL2 | 5326 | 202925_s_at | 0.5846 | 0.0393 | |
| GSE97050 | PLAGL2 | 5326 | A_33_P3328292 | 0.3354 | 0.2032 | |
| SRP007169 | PLAGL2 | 5326 | RNAseq | -0.3421 | 0.2953 | |
| SRP008496 | PLAGL2 | 5326 | RNAseq | -0.2155 | 0.4295 | |
| SRP064894 | PLAGL2 | 5326 | RNAseq | -0.2134 | 0.4083 | |
| SRP133303 | PLAGL2 | 5326 | RNAseq | 0.2052 | 0.3371 | |
| SRP159526 | PLAGL2 | 5326 | RNAseq | 0.4030 | 0.1767 | |
| SRP193095 | PLAGL2 | 5326 | RNAseq | 0.0906 | 0.5045 | |
| SRP219564 | PLAGL2 | 5326 | RNAseq | 0.4974 | 0.2610 | |
| TCGA | PLAGL2 | 5326 | RNAseq | 0.0829 | 0.1823 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by PLAGL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PLAGL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PLAGL2 | 5326 | 15 | 0 | 15 | |
| GSE20123 | PLAGL2 | 5326 | 15 | 0 | 15 | |
| GSE43470 | PLAGL2 | 5326 | 12 | 0 | 31 | |
| GSE46452 | PLAGL2 | 5326 | 29 | 0 | 30 | |
| GSE47630 | PLAGL2 | 5326 | 24 | 1 | 15 | |
| GSE54993 | PLAGL2 | 5326 | 0 | 18 | 52 | |
| GSE54994 | PLAGL2 | 5326 | 26 | 3 | 24 | |
| GSE60625 | PLAGL2 | 5326 | 0 | 0 | 11 | |
| GSE74703 | PLAGL2 | 5326 | 11 | 0 | 25 | |
| GSE74704 | PLAGL2 | 5326 | 10 | 0 | 10 | |
| TCGA | PLAGL2 | 5326 | 49 | 1 | 46 |
Total number of gains: 191; Total number of losses: 23; Total Number of normals: 274.
Somatic mutations of PLAGL2:
Generating mutation plots.
Highly correlated genes for PLAGL2:
Showing top 20/624 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PLAGL2 | FAM161A | 0.825116 | 3 | 0 | 3 |
| PLAGL2 | ANKRD54 | 0.797526 | 3 | 0 | 3 |
| PLAGL2 | FOXN2 | 0.786226 | 3 | 0 | 3 |
| PLAGL2 | MRPL38 | 0.783318 | 3 | 0 | 3 |
| PLAGL2 | GORAB | 0.782553 | 3 | 0 | 3 |
| PLAGL2 | NPLOC4 | 0.777936 | 3 | 0 | 3 |
| PLAGL2 | CPT1C | 0.775196 | 3 | 0 | 3 |
| PLAGL2 | PIF1 | 0.770407 | 3 | 0 | 3 |
| PLAGL2 | UHMK1 | 0.766956 | 3 | 0 | 3 |
| PLAGL2 | YWHAG | 0.759535 | 3 | 0 | 3 |
| PLAGL2 | MASTL | 0.757538 | 3 | 0 | 3 |
| PLAGL2 | VEZT | 0.755981 | 3 | 0 | 3 |
| PLAGL2 | DDX20 | 0.755774 | 3 | 0 | 3 |
| PLAGL2 | PIGU | 0.751126 | 5 | 0 | 4 |
| PLAGL2 | MAD2L2 | 0.75067 | 3 | 0 | 3 |
| PLAGL2 | CYP27C1 | 0.748056 | 3 | 0 | 3 |
| PLAGL2 | SNX13 | 0.746614 | 3 | 0 | 3 |
| PLAGL2 | MRPL45 | 0.745737 | 3 | 0 | 3 |
| PLAGL2 | UHRF1BP1 | 0.744954 | 4 | 0 | 4 |
| PLAGL2 | SENP1 | 0.740124 | 4 | 0 | 4 |
For details and further investigation, click here
