| Full name: proteasome subunit beta 2 | Alias Symbol: HC7-I | ||
| Type: protein-coding gene | Cytoband: 1p34.3 | ||
| Entrez ID: 5690 | HGNC ID: HGNC:9539 | Ensembl Gene: ENSG00000126067 | OMIM ID: 602175 |
| Drug and gene relationship at DGIdb | |||
Expression of PSMB2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PSMB2 | 5690 | 200039_s_at | 0.8881 | 0.0123 | |
| GSE20347 | PSMB2 | 5690 | 200039_s_at | 0.9392 | 0.0002 | |
| GSE23400 | PSMB2 | 5690 | 200039_s_at | 0.8576 | 0.0000 | |
| GSE26886 | PSMB2 | 5690 | 200039_s_at | 1.0383 | 0.0000 | |
| GSE29001 | PSMB2 | 5690 | 200039_s_at | 0.8891 | 0.0274 | |
| GSE38129 | PSMB2 | 5690 | 200039_s_at | 0.9933 | 0.0000 | |
| GSE45670 | PSMB2 | 5690 | 200039_s_at | 0.9745 | 0.0000 | |
| GSE53622 | PSMB2 | 5690 | 10851 | 0.7573 | 0.0000 | |
| GSE53624 | PSMB2 | 5690 | 10851 | 1.2452 | 0.0000 | |
| GSE63941 | PSMB2 | 5690 | 200039_s_at | 0.7875 | 0.0163 | |
| GSE77861 | PSMB2 | 5690 | 200039_s_at | 0.7598 | 0.0595 | |
| GSE97050 | PSMB2 | 5690 | A_23_P170058 | 0.7252 | 0.0786 | |
| SRP007169 | PSMB2 | 5690 | RNAseq | -0.1680 | 0.6949 | |
| SRP008496 | PSMB2 | 5690 | RNAseq | -0.2646 | 0.2290 | |
| SRP064894 | PSMB2 | 5690 | RNAseq | 0.9600 | 0.0000 | |
| SRP133303 | PSMB2 | 5690 | RNAseq | 0.8751 | 0.0000 | |
| SRP159526 | PSMB2 | 5690 | RNAseq | 0.5191 | 0.0034 | |
| SRP193095 | PSMB2 | 5690 | RNAseq | 0.5215 | 0.0000 | |
| SRP219564 | PSMB2 | 5690 | RNAseq | 0.5798 | 0.1291 | |
| TCGA | PSMB2 | 5690 | RNAseq | 0.2703 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by PSMB2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PSMB2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PSMB2 | 5690 | 2 | 5 | 23 | |
| GSE20123 | PSMB2 | 5690 | 2 | 4 | 24 | |
| GSE43470 | PSMB2 | 5690 | 7 | 2 | 34 | |
| GSE46452 | PSMB2 | 5690 | 4 | 1 | 54 | |
| GSE47630 | PSMB2 | 5690 | 8 | 3 | 29 | |
| GSE54993 | PSMB2 | 5690 | 1 | 1 | 68 | |
| GSE54994 | PSMB2 | 5690 | 11 | 2 | 40 | |
| GSE60625 | PSMB2 | 5690 | 0 | 0 | 11 | |
| GSE74703 | PSMB2 | 5690 | 6 | 1 | 29 | |
| GSE74704 | PSMB2 | 5690 | 1 | 0 | 19 | |
| TCGA | PSMB2 | 5690 | 11 | 19 | 66 |
Total number of gains: 53; Total number of losses: 38; Total Number of normals: 397.
Somatic mutations of PSMB2:
Generating mutation plots.
Highly correlated genes for PSMB2:
Showing top 20/2101 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PSMB2 | NTMT1 | 0.776581 | 6 | 0 | 6 |
| PSMB2 | ATP6V1C1 | 0.776185 | 10 | 0 | 10 |
| PSMB2 | ACOT7 | 0.76969 | 12 | 0 | 12 |
| PSMB2 | PYCR2 | 0.767177 | 3 | 0 | 3 |
| PSMB2 | WDR66 | 0.764921 | 7 | 0 | 7 |
| PSMB2 | CKS1B | 0.764424 | 13 | 0 | 13 |
| PSMB2 | PLOD1 | 0.764199 | 10 | 0 | 10 |
| PSMB2 | EBNA1BP2 | 0.764195 | 4 | 0 | 4 |
| PSMB2 | PFDN2 | 0.757801 | 11 | 0 | 11 |
| PSMB2 | MTHFD1L | 0.755045 | 4 | 0 | 4 |
| PSMB2 | MARCKSL1 | 0.754154 | 10 | 0 | 10 |
| PSMB2 | TTYH3 | 0.753415 | 7 | 0 | 7 |
| PSMB2 | SNX10 | 0.752608 | 11 | 0 | 11 |
| PSMB2 | SNAP47 | 0.752579 | 3 | 0 | 3 |
| PSMB2 | C14orf119 | 0.750982 | 3 | 0 | 3 |
| PSMB2 | XPR1 | 0.746864 | 7 | 0 | 6 |
| PSMB2 | SH3PXD2B | 0.745671 | 7 | 0 | 7 |
| PSMB2 | FAM89A | 0.744729 | 3 | 0 | 3 |
| PSMB2 | B3GALT6 | 0.741653 | 6 | 0 | 6 |
| PSMB2 | PSMB3 | 0.741252 | 12 | 0 | 11 |
For details and further investigation, click here
