| Full name: AT-hook DNA binding motif containing 1 | Alias Symbol: DJ159A19.3|RP1-159A19.1 | ||
| Type: protein-coding gene | Cytoband: 1p36.11-p35.3 | ||
| Entrez ID: 27245 | HGNC ID: HGNC:25230 | Ensembl Gene: ENSG00000126705 | OMIM ID: 615790 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of AHDC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AHDC1 | 27245 | 205002_at | -0.6711 | 0.1842 | |
| GSE20347 | AHDC1 | 27245 | 205002_at | -0.8191 | 0.0001 | |
| GSE23400 | AHDC1 | 27245 | 205002_at | -0.4900 | 0.0000 | |
| GSE26886 | AHDC1 | 27245 | 205002_at | -0.1247 | 0.5568 | |
| GSE29001 | AHDC1 | 27245 | 205002_at | -0.4906 | 0.0105 | |
| GSE38129 | AHDC1 | 27245 | 205002_at | -0.6089 | 0.0005 | |
| GSE45670 | AHDC1 | 27245 | 205002_at | -0.4977 | 0.0093 | |
| GSE53622 | AHDC1 | 27245 | 37270 | -0.7899 | 0.0000 | |
| GSE53624 | AHDC1 | 27245 | 37270 | -0.7248 | 0.0000 | |
| GSE63941 | AHDC1 | 27245 | 205002_at | 0.0184 | 0.9600 | |
| GSE77861 | AHDC1 | 27245 | 229379_at | -0.2082 | 0.0664 | |
| GSE97050 | AHDC1 | 27245 | A_33_P3215797 | -0.2259 | 0.3436 | |
| SRP007169 | AHDC1 | 27245 | RNAseq | -0.4271 | 0.2995 | |
| SRP008496 | AHDC1 | 27245 | RNAseq | -0.6155 | 0.0897 | |
| SRP064894 | AHDC1 | 27245 | RNAseq | -1.1288 | 0.0000 | |
| SRP133303 | AHDC1 | 27245 | RNAseq | -0.9757 | 0.0000 | |
| SRP159526 | AHDC1 | 27245 | RNAseq | -0.6576 | 0.0504 | |
| SRP193095 | AHDC1 | 27245 | RNAseq | -0.7501 | 0.0008 | |
| SRP219564 | AHDC1 | 27245 | RNAseq | -1.4961 | 0.0016 | |
| TCGA | AHDC1 | 27245 | RNAseq | -0.0059 | 0.9189 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by AHDC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AHDC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AHDC1 | 27245 | 0 | 6 | 24 | |
| GSE20123 | AHDC1 | 27245 | 0 | 5 | 25 | |
| GSE43470 | AHDC1 | 27245 | 4 | 6 | 33 | |
| GSE46452 | AHDC1 | 27245 | 5 | 1 | 53 | |
| GSE47630 | AHDC1 | 27245 | 8 | 3 | 29 | |
| GSE54993 | AHDC1 | 27245 | 2 | 1 | 67 | |
| GSE54994 | AHDC1 | 27245 | 10 | 4 | 39 | |
| GSE60625 | AHDC1 | 27245 | 0 | 0 | 11 | |
| GSE74703 | AHDC1 | 27245 | 3 | 4 | 29 | |
| GSE74704 | AHDC1 | 27245 | 0 | 0 | 20 | |
| TCGA | AHDC1 | 27245 | 11 | 23 | 62 |
Total number of gains: 43; Total number of losses: 53; Total Number of normals: 392.
Somatic mutations of AHDC1:
Generating mutation plots.
Highly correlated genes for AHDC1:
Showing top 20/1115 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AHDC1 | SMDT1 | 0.724805 | 3 | 0 | 3 |
| AHDC1 | FAM95B1 | 0.720381 | 3 | 0 | 3 |
| AHDC1 | C5orf66-AS1 | 0.716369 | 4 | 0 | 4 |
| AHDC1 | PLEKHN1 | 0.715921 | 6 | 0 | 5 |
| AHDC1 | ATG9B | 0.715179 | 6 | 0 | 6 |
| AHDC1 | AIF1L | 0.706528 | 5 | 0 | 5 |
| AHDC1 | RAET1E | 0.704377 | 5 | 0 | 5 |
| AHDC1 | TTC9 | 0.694076 | 9 | 0 | 8 |
| AHDC1 | MUC20 | 0.692238 | 5 | 0 | 5 |
| AHDC1 | TPRN | 0.691787 | 4 | 0 | 4 |
| AHDC1 | B3GALT4 | 0.689361 | 7 | 0 | 7 |
| AHDC1 | CLDND2 | 0.689301 | 3 | 0 | 3 |
| AHDC1 | TMEM38A | 0.688083 | 3 | 0 | 3 |
| AHDC1 | VSIG10L | 0.687069 | 6 | 0 | 5 |
| AHDC1 | IL12A-AS1 | 0.684893 | 5 | 0 | 5 |
| AHDC1 | SLURP1 | 0.683602 | 9 | 0 | 9 |
| AHDC1 | ZHX1 | 0.677536 | 6 | 0 | 5 |
| AHDC1 | SPRR2B | 0.675006 | 3 | 0 | 3 |
| AHDC1 | SPINK7 | 0.674788 | 5 | 0 | 5 |
| AHDC1 | PPL | 0.674445 | 9 | 0 | 9 |
For details and further investigation, click here
