| Full name: zinc fingers and homeoboxes 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 8q24.13 | ||
| Entrez ID: 11244 | HGNC ID: HGNC:12871 | Ensembl Gene: ENSG00000165156 | OMIM ID: 604764 |
| Drug and gene relationship at DGIdb | |||
Expression of ZHX1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZHX1 | 11244 | 223213_s_at | -0.4887 | 0.5068 | |
| GSE26886 | ZHX1 | 11244 | 223213_s_at | -1.2462 | 0.0000 | |
| GSE45670 | ZHX1 | 11244 | 223213_s_at | -0.6075 | 0.0038 | |
| GSE53622 | ZHX1 | 11244 | 81952 | -0.8715 | 0.0000 | |
| GSE53624 | ZHX1 | 11244 | 81952 | -0.8036 | 0.0000 | |
| GSE63941 | ZHX1 | 11244 | 223213_s_at | -1.0073 | 0.1226 | |
| GSE77861 | ZHX1 | 11244 | 223214_s_at | -1.4653 | 0.0010 | |
| GSE97050 | ZHX1 | 11244 | A_23_P43150 | -0.4277 | 0.1895 | |
| SRP007169 | ZHX1 | 11244 | RNAseq | -2.1281 | 0.0000 | |
| SRP008496 | ZHX1 | 11244 | RNAseq | -1.6713 | 0.0000 | |
| SRP064894 | ZHX1 | 11244 | RNAseq | -0.9633 | 0.0000 | |
| SRP133303 | ZHX1 | 11244 | RNAseq | -0.7736 | 0.0000 | |
| SRP159526 | ZHX1 | 11244 | RNAseq | -1.5075 | 0.0000 | |
| SRP193095 | ZHX1 | 11244 | RNAseq | -1.3198 | 0.0000 | |
| SRP219564 | ZHX1 | 11244 | RNAseq | -0.5041 | 0.3154 | |
| TCGA | ZHX1 | 11244 | RNAseq | -0.0183 | 0.7614 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by ZHX1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZHX1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZHX1 | 11244 | 19 | 1 | 10 | |
| GSE20123 | ZHX1 | 11244 | 20 | 1 | 9 | |
| GSE43470 | ZHX1 | 11244 | 22 | 0 | 21 | |
| GSE46452 | ZHX1 | 11244 | 27 | 0 | 32 | |
| GSE47630 | ZHX1 | 11244 | 24 | 0 | 16 | |
| GSE54993 | ZHX1 | 11244 | 0 | 21 | 49 | |
| GSE54994 | ZHX1 | 11244 | 37 | 1 | 15 | |
| GSE60625 | ZHX1 | 11244 | 0 | 4 | 7 | |
| GSE74703 | ZHX1 | 11244 | 19 | 0 | 17 | |
| GSE74704 | ZHX1 | 11244 | 13 | 1 | 6 | |
| TCGA | ZHX1 | 11244 | 67 | 1 | 28 |
Total number of gains: 248; Total number of losses: 30; Total Number of normals: 210.
Somatic mutations of ZHX1:
Generating mutation plots.
Highly correlated genes for ZHX1:
Showing top 20/1282 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZHX1 | GBP6 | 0.848518 | 3 | 0 | 3 |
| ZHX1 | HBP1 | 0.830097 | 4 | 0 | 4 |
| ZHX1 | SNORA68 | 0.81687 | 3 | 0 | 3 |
| ZHX1 | ACAA1 | 0.806398 | 5 | 0 | 5 |
| ZHX1 | EMP1 | 0.776959 | 5 | 0 | 5 |
| ZHX1 | ABLIM1 | 0.768085 | 6 | 0 | 6 |
| ZHX1 | KLF8 | 0.76551 | 6 | 0 | 6 |
| ZHX1 | SUMF1 | 0.76371 | 4 | 0 | 4 |
| ZHX1 | FAM214A | 0.762334 | 5 | 0 | 5 |
| ZHX1 | NSG1 | 0.761804 | 3 | 0 | 3 |
| ZHX1 | C5orf66-AS1 | 0.759375 | 5 | 0 | 5 |
| ZHX1 | LRRFIP2 | 0.756207 | 8 | 0 | 8 |
| ZHX1 | NCOA2 | 0.753567 | 7 | 0 | 7 |
| ZHX1 | CRCT1 | 0.752399 | 5 | 0 | 5 |
| ZHX1 | PRSS2 | 0.751648 | 3 | 0 | 3 |
| ZHX1 | ACOX3 | 0.750903 | 7 | 0 | 7 |
| ZHX1 | MGLL | 0.750248 | 6 | 0 | 6 |
| ZHX1 | CHP1 | 0.74331 | 5 | 0 | 5 |
| ZHX1 | ALDH9A1 | 0.743048 | 7 | 0 | 7 |
| ZHX1 | SPINK7 | 0.742432 | 5 | 0 | 5 |
For details and further investigation, click here
