| Full name: growth factor, augmenter of liver regeneration | Alias Symbol: HSS|ERV1|ALR|HERV1|HPO1|HPO2 | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 2671 | HGNC ID: HGNC:4236 | Ensembl Gene: ENSG00000127554 | OMIM ID: 600924 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of GFER:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GFER | 2671 | 204659_s_at | 0.1358 | 0.6838 | |
| GSE20347 | GFER | 2671 | 204660_at | 0.0687 | 0.4324 | |
| GSE23400 | GFER | 2671 | 204660_at | -0.0661 | 0.0645 | |
| GSE26886 | GFER | 2671 | 204660_at | 0.2125 | 0.0924 | |
| GSE29001 | GFER | 2671 | 204659_s_at | 0.1029 | 0.5524 | |
| GSE38129 | GFER | 2671 | 204659_s_at | 0.0824 | 0.5355 | |
| GSE45670 | GFER | 2671 | 204659_s_at | 0.1568 | 0.2070 | |
| GSE63941 | GFER | 2671 | 204659_s_at | -0.1835 | 0.7013 | |
| GSE77861 | GFER | 2671 | 204660_at | -0.0809 | 0.5623 | |
| GSE97050 | GFER | 2671 | A_24_P31003 | 0.0989 | 0.7642 | |
| SRP007169 | GFER | 2671 | RNAseq | -0.1508 | 0.6977 | |
| SRP008496 | GFER | 2671 | RNAseq | 0.2329 | 0.3998 | |
| SRP064894 | GFER | 2671 | RNAseq | 0.5848 | 0.0636 | |
| SRP133303 | GFER | 2671 | RNAseq | 0.4474 | 0.0022 | |
| SRP159526 | GFER | 2671 | RNAseq | 0.3788 | 0.0508 | |
| SRP193095 | GFER | 2671 | RNAseq | 0.1811 | 0.3327 | |
| SRP219564 | GFER | 2671 | RNAseq | 0.7898 | 0.1243 | |
| TCGA | GFER | 2671 | RNAseq | 0.0313 | 0.6187 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GFER expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of GFER:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GFER | 2671 | 5 | 5 | 20 | |
| GSE20123 | GFER | 2671 | 5 | 4 | 21 | |
| GSE43470 | GFER | 2671 | 4 | 7 | 32 | |
| GSE46452 | GFER | 2671 | 38 | 1 | 20 | |
| GSE47630 | GFER | 2671 | 13 | 6 | 21 | |
| GSE54993 | GFER | 2671 | 3 | 5 | 62 | |
| GSE54994 | GFER | 2671 | 5 | 9 | 39 | |
| GSE60625 | GFER | 2671 | 4 | 0 | 7 | |
| GSE74703 | GFER | 2671 | 4 | 5 | 27 | |
| GSE74704 | GFER | 2671 | 3 | 2 | 15 | |
| TCGA | GFER | 2671 | 19 | 14 | 63 |
Total number of gains: 103; Total number of losses: 58; Total Number of normals: 327.
Somatic mutations of GFER:
Generating mutation plots.
Highly correlated genes for GFER:
Showing top 20/101 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GFER | AMER3 | 0.69565 | 3 | 0 | 3 |
| GFER | PAGE1 | 0.676912 | 3 | 0 | 3 |
| GFER | UTS2 | 0.673448 | 3 | 0 | 3 |
| GFER | PEAR1 | 0.659349 | 3 | 0 | 3 |
| GFER | TNFRSF12A | 0.649904 | 3 | 0 | 3 |
| GFER | GP9 | 0.631505 | 4 | 0 | 3 |
| GFER | CNIH2 | 0.628641 | 3 | 0 | 3 |
| GFER | BIRC7 | 0.627011 | 4 | 0 | 4 |
| GFER | SUGCT | 0.624873 | 3 | 0 | 3 |
| GFER | BAIAP2L2 | 0.624542 | 3 | 0 | 3 |
| GFER | DNAAF3 | 0.622051 | 3 | 0 | 3 |
| GFER | TSPAN10 | 0.621785 | 4 | 0 | 3 |
| GFER | ENDOV | 0.61703 | 3 | 0 | 3 |
| GFER | DDRGK1 | 0.615257 | 3 | 0 | 3 |
| GFER | LTB4R2 | 0.612253 | 4 | 0 | 4 |
| GFER | CCDC88B | 0.611248 | 4 | 0 | 4 |
| GFER | SH2D5 | 0.609643 | 4 | 0 | 3 |
| GFER | FZD9 | 0.609292 | 4 | 0 | 3 |
| GFER | FSCN1 | 0.609286 | 3 | 0 | 3 |
| GFER | SEZ6L2 | 0.603865 | 3 | 0 | 3 |
For details and further investigation, click here
