| Full name: autocrine motility factor receptor | Alias Symbol: RNF45|gp78 | ||
| Type: protein-coding gene | Cytoband: 16q13 | ||
| Entrez ID: 267 | HGNC ID: HGNC:463 | Ensembl Gene: ENSG00000159461 | OMIM ID: 603243 |
| Drug and gene relationship at DGIdb | |||
Expression of AMFR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AMFR | 267 | 202204_s_at | 0.0189 | 0.9798 | |
| GSE20347 | AMFR | 267 | 202204_s_at | -0.6647 | 0.0000 | |
| GSE23400 | AMFR | 267 | 202204_s_at | -0.4332 | 0.0000 | |
| GSE26886 | AMFR | 267 | 202204_s_at | -1.7901 | 0.0000 | |
| GSE29001 | AMFR | 267 | 202203_s_at | -1.5741 | 0.0002 | |
| GSE38129 | AMFR | 267 | 202204_s_at | -0.4293 | 0.0018 | |
| GSE45670 | AMFR | 267 | 202204_s_at | -0.2806 | 0.0824 | |
| GSE53622 | AMFR | 267 | 45163 | -0.6615 | 0.0000 | |
| GSE53624 | AMFR | 267 | 127505 | -0.8166 | 0.0000 | |
| GSE63941 | AMFR | 267 | 202204_s_at | -1.3216 | 0.0072 | |
| GSE77861 | AMFR | 267 | 202204_s_at | -0.2510 | 0.3524 | |
| GSE97050 | AMFR | 267 | A_24_P135444 | -0.3685 | 0.2411 | |
| SRP007169 | AMFR | 267 | RNAseq | -2.8290 | 0.0000 | |
| SRP008496 | AMFR | 267 | RNAseq | -2.3094 | 0.0000 | |
| SRP064894 | AMFR | 267 | RNAseq | -1.0715 | 0.0000 | |
| SRP133303 | AMFR | 267 | RNAseq | -0.7360 | 0.0000 | |
| SRP159526 | AMFR | 267 | RNAseq | -0.6439 | 0.0383 | |
| SRP193095 | AMFR | 267 | RNAseq | -0.8399 | 0.0000 | |
| SRP219564 | AMFR | 267 | RNAseq | -0.5600 | 0.0901 | |
| TCGA | AMFR | 267 | RNAseq | -0.0498 | 0.2674 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by AMFR expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AMFR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AMFR | 267 | 5 | 0 | 25 | |
| GSE20123 | AMFR | 267 | 5 | 0 | 25 | |
| GSE43470 | AMFR | 267 | 2 | 7 | 34 | |
| GSE46452 | AMFR | 267 | 38 | 1 | 20 | |
| GSE47630 | AMFR | 267 | 10 | 8 | 22 | |
| GSE54993 | AMFR | 267 | 2 | 4 | 64 | |
| GSE54994 | AMFR | 267 | 7 | 10 | 36 | |
| GSE60625 | AMFR | 267 | 4 | 0 | 7 | |
| GSE74703 | AMFR | 267 | 2 | 4 | 30 | |
| GSE74704 | AMFR | 267 | 4 | 0 | 16 | |
| TCGA | AMFR | 267 | 25 | 12 | 59 |
Total number of gains: 104; Total number of losses: 46; Total Number of normals: 338.
Somatic mutations of AMFR:
Generating mutation plots.
Highly correlated genes for AMFR:
Showing top 20/946 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AMFR | ITCH | 0.711763 | 9 | 0 | 9 |
| AMFR | DOK4 | 0.706517 | 11 | 0 | 11 |
| AMFR | SORT1 | 0.70603 | 8 | 0 | 8 |
| AMFR | MFSD5 | 0.698992 | 11 | 0 | 10 |
| AMFR | SNX24 | 0.696589 | 11 | 0 | 10 |
| AMFR | RMND5B | 0.693159 | 9 | 0 | 8 |
| AMFR | CRCT1 | 0.692481 | 11 | 0 | 11 |
| AMFR | CLIC3 | 0.691875 | 9 | 0 | 8 |
| AMFR | MORN3 | 0.690839 | 3 | 0 | 3 |
| AMFR | GYS2 | 0.689609 | 10 | 0 | 8 |
| AMFR | CARHSP1 | 0.688657 | 9 | 0 | 8 |
| AMFR | MXD1 | 0.687889 | 11 | 0 | 11 |
| AMFR | TOM1 | 0.68779 | 10 | 0 | 10 |
| AMFR | TMOD3 | 0.687283 | 11 | 0 | 10 |
| AMFR | GALE | 0.683654 | 9 | 0 | 7 |
| AMFR | FAM214A | 0.682937 | 4 | 0 | 4 |
| AMFR | CRISP3 | 0.682606 | 10 | 0 | 9 |
| AMFR | SH3GL1 | 0.682468 | 10 | 0 | 9 |
| AMFR | PMM1 | 0.681652 | 11 | 0 | 10 |
| AMFR | AGFG2 | 0.681259 | 10 | 0 | 9 |
For details and further investigation, click here
