| Full name: UDP-galactose-4-epimerase | Alias Symbol: SDR1E1 | ||
| Type: protein-coding gene | Cytoband: 1p36.11 | ||
| Entrez ID: 2582 | HGNC ID: HGNC:4116 | Ensembl Gene: ENSG00000117308 | OMIM ID: 606953 |
| Drug and gene relationship at DGIdb | |||
Expression of GALE:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GALE | 2582 | 202528_at | -0.2984 | 0.7584 | |
| GSE20347 | GALE | 2582 | 202528_at | -1.3922 | 0.0000 | |
| GSE23400 | GALE | 2582 | 202528_at | -1.0725 | 0.0000 | |
| GSE26886 | GALE | 2582 | 202528_at | -1.6381 | 0.0000 | |
| GSE29001 | GALE | 2582 | 202528_at | -1.4943 | 0.0005 | |
| GSE38129 | GALE | 2582 | 202528_at | -0.9880 | 0.0003 | |
| GSE45670 | GALE | 2582 | 202528_at | -0.5207 | 0.0296 | |
| GSE53622 | GALE | 2582 | 85926 | -1.1826 | 0.0000 | |
| GSE53624 | GALE | 2582 | 85926 | -1.8496 | 0.0000 | |
| GSE63941 | GALE | 2582 | 202528_at | 1.3978 | 0.0804 | |
| GSE77861 | GALE | 2582 | 202528_at | -0.9784 | 0.0020 | |
| GSE97050 | GALE | 2582 | A_23_P160154 | 0.3560 | 0.5939 | |
| SRP007169 | GALE | 2582 | RNAseq | -3.4680 | 0.0000 | |
| SRP008496 | GALE | 2582 | RNAseq | -3.5265 | 0.0000 | |
| SRP064894 | GALE | 2582 | RNAseq | -1.4963 | 0.0000 | |
| SRP133303 | GALE | 2582 | RNAseq | -0.8375 | 0.0011 | |
| SRP159526 | GALE | 2582 | RNAseq | -1.5398 | 0.0000 | |
| SRP193095 | GALE | 2582 | RNAseq | -1.6014 | 0.0000 | |
| SRP219564 | GALE | 2582 | RNAseq | -1.2606 | 0.0663 | |
| TCGA | GALE | 2582 | RNAseq | -0.3695 | 0.0004 |
Upregulated datasets: 0; Downregulated datasets: 11.
Survival by GALE expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GALE:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GALE | 2582 | 0 | 5 | 25 | |
| GSE20123 | GALE | 2582 | 0 | 4 | 26 | |
| GSE43470 | GALE | 2582 | 2 | 6 | 35 | |
| GSE46452 | GALE | 2582 | 5 | 1 | 53 | |
| GSE47630 | GALE | 2582 | 8 | 3 | 29 | |
| GSE54993 | GALE | 2582 | 2 | 1 | 67 | |
| GSE54994 | GALE | 2582 | 11 | 4 | 38 | |
| GSE60625 | GALE | 2582 | 0 | 0 | 11 | |
| GSE74703 | GALE | 2582 | 1 | 4 | 31 | |
| GSE74704 | GALE | 2582 | 0 | 0 | 20 | |
| TCGA | GALE | 2582 | 9 | 24 | 63 |
Total number of gains: 38; Total number of losses: 52; Total Number of normals: 398.
Somatic mutations of GALE:
Generating mutation plots.
Highly correlated genes for GALE:
Showing top 20/1572 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GALE | FAM95B1 | 0.848196 | 3 | 0 | 3 |
| GALE | TP53I3 | 0.799701 | 11 | 0 | 11 |
| GALE | TMEM154 | 0.792766 | 6 | 0 | 6 |
| GALE | SH3GL1 | 0.791942 | 11 | 0 | 11 |
| GALE | CWH43 | 0.788504 | 10 | 0 | 10 |
| GALE | RER1 | 0.787972 | 10 | 0 | 10 |
| GALE | SNORA68 | 0.786342 | 3 | 0 | 3 |
| GALE | CES2 | 0.781241 | 8 | 0 | 8 |
| GALE | PLIN3 | 0.780774 | 11 | 0 | 11 |
| GALE | BLNK | 0.780258 | 11 | 0 | 11 |
| GALE | SCNN1B | 0.776633 | 10 | 0 | 10 |
| GALE | FAM214A | 0.768295 | 5 | 0 | 5 |
| GALE | PADI1 | 0.767397 | 8 | 0 | 8 |
| GALE | MXD1 | 0.767346 | 11 | 0 | 10 |
| GALE | ORMDL2 | 0.766948 | 9 | 0 | 9 |
| GALE | MFSD5 | 0.765993 | 11 | 0 | 11 |
| GALE | WWC1 | 0.765553 | 12 | 0 | 12 |
| GALE | ESPL1 | 0.765043 | 11 | 0 | 11 |
| GALE | CHP1 | 0.762932 | 10 | 0 | 10 |
| GALE | RAET1E | 0.759405 | 6 | 0 | 6 |
For details and further investigation, click here
