| Full name: membrane spanning 4-domains A6A | Alias Symbol: CD20L3 | ||
| Type: protein-coding gene | Cytoband: 11q12.2 | ||
| Entrez ID: 64231 | HGNC ID: HGNC:13375 | Ensembl Gene: ENSG00000110077 | OMIM ID: 606548 |
| Drug and gene relationship at DGIdb | |||
Expression of MS4A6A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MS4A6A | 64231 | 223922_x_at | -0.3379 | 0.7553 | |
| GSE20347 | MS4A6A | 64231 | 219666_at | 0.0176 | 0.9293 | |
| GSE23400 | MS4A6A | 64231 | 219666_at | 0.2715 | 0.0032 | |
| GSE26886 | MS4A6A | 64231 | 219666_at | -1.0124 | 0.0075 | |
| GSE29001 | MS4A6A | 64231 | 219666_at | 0.3766 | 0.3202 | |
| GSE38129 | MS4A6A | 64231 | 219666_at | -0.0687 | 0.7571 | |
| GSE45670 | MS4A6A | 64231 | 223280_x_at | -0.7475 | 0.0107 | |
| GSE53622 | MS4A6A | 64231 | 87424 | -0.1171 | 0.4330 | |
| GSE53624 | MS4A6A | 64231 | 87424 | -0.0359 | 0.8622 | |
| GSE63941 | MS4A6A | 64231 | 223922_x_at | 0.4232 | 0.0140 | |
| GSE77861 | MS4A6A | 64231 | 223922_x_at | -0.2162 | 0.2745 | |
| GSE97050 | MS4A6A | 64231 | A_23_P36120 | 0.4290 | 0.4368 | |
| SRP007169 | MS4A6A | 64231 | RNAseq | 1.1597 | 0.0726 | |
| SRP008496 | MS4A6A | 64231 | RNAseq | 0.8306 | 0.0450 | |
| SRP064894 | MS4A6A | 64231 | RNAseq | 0.7881 | 0.0447 | |
| SRP133303 | MS4A6A | 64231 | RNAseq | 0.2806 | 0.4213 | |
| SRP159526 | MS4A6A | 64231 | RNAseq | 0.2338 | 0.7657 | |
| SRP193095 | MS4A6A | 64231 | RNAseq | -0.2501 | 0.2416 | |
| SRP219564 | MS4A6A | 64231 | RNAseq | 1.2903 | 0.0459 | |
| TCGA | MS4A6A | 64231 | RNAseq | 0.0678 | 0.6278 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by MS4A6A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MS4A6A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MS4A6A | 64231 | 1 | 5 | 24 | |
| GSE20123 | MS4A6A | 64231 | 1 | 5 | 24 | |
| GSE43470 | MS4A6A | 64231 | 2 | 5 | 36 | |
| GSE46452 | MS4A6A | 64231 | 8 | 4 | 47 | |
| GSE47630 | MS4A6A | 64231 | 3 | 8 | 29 | |
| GSE54993 | MS4A6A | 64231 | 3 | 0 | 67 | |
| GSE54994 | MS4A6A | 64231 | 5 | 5 | 43 | |
| GSE60625 | MS4A6A | 64231 | 0 | 3 | 8 | |
| GSE74703 | MS4A6A | 64231 | 2 | 3 | 31 | |
| GSE74704 | MS4A6A | 64231 | 1 | 4 | 15 | |
| TCGA | MS4A6A | 64231 | 14 | 10 | 72 |
Total number of gains: 40; Total number of losses: 52; Total Number of normals: 396.
Somatic mutations of MS4A6A:
Generating mutation plots.
Highly correlated genes for MS4A6A:
Showing top 20/491 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MS4A6A | HLA-DOA | 0.787733 | 5 | 0 | 5 |
| MS4A6A | GIMAP5 | 0.787189 | 4 | 0 | 4 |
| MS4A6A | MPEG1 | 0.786283 | 7 | 0 | 6 |
| MS4A6A | GIMAP1 | 0.785286 | 7 | 0 | 7 |
| MS4A6A | GPR34 | 0.784844 | 7 | 0 | 7 |
| MS4A6A | CD163 | 0.773685 | 9 | 0 | 9 |
| MS4A6A | CSF1R | 0.769123 | 12 | 0 | 11 |
| MS4A6A | GIMAP7 | 0.756719 | 7 | 0 | 7 |
| MS4A6A | C1QC | 0.756527 | 7 | 0 | 7 |
| MS4A6A | C19orf38 | 0.754003 | 3 | 0 | 3 |
| MS4A6A | C1QA | 0.753803 | 11 | 0 | 11 |
| MS4A6A | NOA1 | 0.749514 | 3 | 0 | 3 |
| MS4A6A | HLA-DPA1 | 0.743204 | 10 | 0 | 9 |
| MS4A6A | MRC1 | 0.739333 | 8 | 0 | 8 |
| MS4A6A | CERKL | 0.738228 | 3 | 0 | 3 |
| MS4A6A | C1QB | 0.73713 | 10 | 0 | 9 |
| MS4A6A | ARHGAP15 | 0.736042 | 4 | 0 | 4 |
| MS4A6A | HLA-DMB | 0.73553 | 10 | 0 | 10 |
| MS4A6A | CD53 | 0.728478 | 9 | 0 | 8 |
| MS4A6A | RPS9 | 0.7267 | 3 | 0 | 3 |
For details and further investigation, click here
