| Full name: tweety family member 2 | Alias Symbol: C17orf29 | ||
| Type: protein-coding gene | Cytoband: 17q25.1 | ||
| Entrez ID: 94015 | HGNC ID: HGNC:13877 | Ensembl Gene: ENSG00000141540 | OMIM ID: 608855 |
| Drug and gene relationship at DGIdb | |||
Expression of TTYH2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TTYH2 | 94015 | 223741_s_at | 0.6117 | 0.2920 | |
| GSE26886 | TTYH2 | 94015 | 223741_s_at | 1.7051 | 0.0000 | |
| GSE45670 | TTYH2 | 94015 | 223741_s_at | 0.3127 | 0.3811 | |
| GSE53622 | TTYH2 | 94015 | 149349 | 0.5660 | 0.0008 | |
| GSE53624 | TTYH2 | 94015 | 149349 | 0.7522 | 0.0000 | |
| GSE63941 | TTYH2 | 94015 | 223741_s_at | 0.8869 | 0.3598 | |
| GSE77861 | TTYH2 | 94015 | 232042_at | 0.0078 | 0.9535 | |
| GSE97050 | TTYH2 | 94015 | A_23_P66432 | 0.0292 | 0.9010 | |
| SRP007169 | TTYH2 | 94015 | RNAseq | 2.9635 | 0.0032 | |
| SRP064894 | TTYH2 | 94015 | RNAseq | 0.9192 | 0.0010 | |
| SRP133303 | TTYH2 | 94015 | RNAseq | 0.1890 | 0.4476 | |
| SRP159526 | TTYH2 | 94015 | RNAseq | 0.7619 | 0.0860 | |
| SRP193095 | TTYH2 | 94015 | RNAseq | 1.3828 | 0.0000 | |
| SRP219564 | TTYH2 | 94015 | RNAseq | 1.3477 | 0.0028 | |
| TCGA | TTYH2 | 94015 | RNAseq | 0.1384 | 0.2932 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by TTYH2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TTYH2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TTYH2 | 94015 | 3 | 2 | 25 | |
| GSE20123 | TTYH2 | 94015 | 3 | 2 | 25 | |
| GSE43470 | TTYH2 | 94015 | 6 | 3 | 34 | |
| GSE46452 | TTYH2 | 94015 | 33 | 0 | 26 | |
| GSE47630 | TTYH2 | 94015 | 8 | 1 | 31 | |
| GSE54993 | TTYH2 | 94015 | 2 | 5 | 63 | |
| GSE54994 | TTYH2 | 94015 | 10 | 4 | 39 | |
| GSE60625 | TTYH2 | 94015 | 6 | 0 | 5 | |
| GSE74703 | TTYH2 | 94015 | 6 | 1 | 29 | |
| GSE74704 | TTYH2 | 94015 | 3 | 1 | 16 | |
| TCGA | TTYH2 | 94015 | 32 | 10 | 54 |
Total number of gains: 112; Total number of losses: 29; Total Number of normals: 347.
Somatic mutations of TTYH2:
Generating mutation plots.
Highly correlated genes for TTYH2:
Showing top 20/965 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TTYH2 | LRRK1 | 0.76908 | 3 | 0 | 3 |
| TTYH2 | CD180 | 0.764308 | 3 | 0 | 3 |
| TTYH2 | C1orf216 | 0.743965 | 6 | 0 | 6 |
| TTYH2 | ANGPTL6 | 0.741594 | 3 | 0 | 3 |
| TTYH2 | RAB3A | 0.734186 | 3 | 0 | 3 |
| TTYH2 | ZNF362 | 0.725806 | 3 | 0 | 3 |
| TTYH2 | NFE2L3 | 0.72535 | 3 | 0 | 3 |
| TTYH2 | ASB2 | 0.722617 | 3 | 0 | 3 |
| TTYH2 | NCKIPSD | 0.722234 | 3 | 0 | 3 |
| TTYH2 | LRP5L | 0.716825 | 3 | 0 | 3 |
| TTYH2 | CLIC2 | 0.713475 | 3 | 0 | 3 |
| TTYH2 | COL4A1 | 0.713289 | 5 | 0 | 4 |
| TTYH2 | BRD9 | 0.711192 | 3 | 0 | 3 |
| TTYH2 | EXOSC8 | 0.710177 | 3 | 0 | 3 |
| TTYH2 | PGM2L1 | 0.709937 | 4 | 0 | 4 |
| TTYH2 | SSBP4 | 0.708778 | 4 | 0 | 4 |
| TTYH2 | STK3 | 0.704855 | 4 | 0 | 4 |
| TTYH2 | DOCK11 | 0.699051 | 4 | 0 | 3 |
| TTYH2 | GNA12 | 0.698848 | 6 | 0 | 6 |
| TTYH2 | SPRED2 | 0.696485 | 3 | 0 | 3 |
For details and further investigation, click here
