| Full name: ankyrin repeat domain 2 | Alias Symbol: ARPP | ||
| Type: protein-coding gene | Cytoband: 10q24.2 | ||
| Entrez ID: 26287 | HGNC ID: HGNC:495 | Ensembl Gene: ENSG00000165887 | OMIM ID: 610734 |
| Drug and gene relationship at DGIdb | |||
Expression of ANKRD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANKRD2 | 26287 | 221232_s_at | 0.0580 | 0.8501 | |
| GSE20347 | ANKRD2 | 26287 | 221232_s_at | -0.0351 | 0.6963 | |
| GSE23400 | ANKRD2 | 26287 | 221232_s_at | -0.1023 | 0.0085 | |
| GSE26886 | ANKRD2 | 26287 | 221232_s_at | 0.1602 | 0.1393 | |
| GSE29001 | ANKRD2 | 26287 | 221232_s_at | -0.2431 | 0.0840 | |
| GSE38129 | ANKRD2 | 26287 | 221232_s_at | -0.1025 | 0.3247 | |
| GSE45670 | ANKRD2 | 26287 | 221232_s_at | 0.0140 | 0.9170 | |
| GSE53622 | ANKRD2 | 26287 | 148443 | 0.3543 | 0.0005 | |
| GSE53624 | ANKRD2 | 26287 | 148443 | 0.3417 | 0.0000 | |
| GSE63941 | ANKRD2 | 26287 | 221232_s_at | 0.8555 | 0.2297 | |
| GSE77861 | ANKRD2 | 26287 | 221232_s_at | -0.0449 | 0.7986 | |
| GSE97050 | ANKRD2 | 26287 | A_33_P3278362 | -0.5089 | 0.3207 | |
| TCGA | ANKRD2 | 26287 | RNAseq | 1.2049 | 0.0375 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ANKRD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANKRD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANKRD2 | 26287 | 1 | 8 | 21 | |
| GSE20123 | ANKRD2 | 26287 | 1 | 7 | 22 | |
| GSE43470 | ANKRD2 | 26287 | 0 | 7 | 36 | |
| GSE46452 | ANKRD2 | 26287 | 0 | 11 | 48 | |
| GSE47630 | ANKRD2 | 26287 | 2 | 14 | 24 | |
| GSE54993 | ANKRD2 | 26287 | 8 | 0 | 62 | |
| GSE54994 | ANKRD2 | 26287 | 2 | 11 | 40 | |
| GSE60625 | ANKRD2 | 26287 | 0 | 0 | 11 | |
| GSE74703 | ANKRD2 | 26287 | 0 | 5 | 31 | |
| GSE74704 | ANKRD2 | 26287 | 0 | 4 | 16 | |
| TCGA | ANKRD2 | 26287 | 5 | 28 | 63 |
Total number of gains: 19; Total number of losses: 95; Total Number of normals: 374.
Somatic mutations of ANKRD2:
Generating mutation plots.
Highly correlated genes for ANKRD2:
Showing top 20/376 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANKRD2 | SLC22A11 | 0.703458 | 5 | 0 | 5 |
| ANKRD2 | C6orf223 | 0.677567 | 3 | 0 | 3 |
| ANKRD2 | CLCA1 | 0.677384 | 5 | 0 | 4 |
| ANKRD2 | CLDN18 | 0.673734 | 3 | 0 | 3 |
| ANKRD2 | CA8 | 0.659367 | 3 | 0 | 3 |
| ANKRD2 | DEFB128 | 0.659256 | 3 | 0 | 3 |
| ANKRD2 | FNDC8 | 0.657309 | 5 | 0 | 4 |
| ANKRD2 | STMN2 | 0.654074 | 4 | 0 | 3 |
| ANKRD2 | C9orf131 | 0.6523 | 4 | 0 | 3 |
| ANKRD2 | ZNF280A | 0.650848 | 3 | 0 | 3 |
| ANKRD2 | ZNF81 | 0.64648 | 3 | 0 | 3 |
| ANKRD2 | NOS1 | 0.645556 | 5 | 0 | 5 |
| ANKRD2 | ASPDH | 0.638945 | 5 | 0 | 4 |
| ANKRD2 | MYOG | 0.635993 | 8 | 0 | 5 |
| ANKRD2 | CACNA1H | 0.635396 | 4 | 0 | 4 |
| ANKRD2 | TAS2R7 | 0.634129 | 4 | 0 | 4 |
| ANKRD2 | ART4 | 0.633405 | 4 | 0 | 3 |
| ANKRD2 | GNG13 | 0.63304 | 5 | 0 | 5 |
| ANKRD2 | PRKG1 | 0.630638 | 3 | 0 | 3 |
| ANKRD2 | OLIG3 | 0.62969 | 4 | 0 | 3 |
For details and further investigation, click here
