| Full name: MOB kinase activator 3A | Alias Symbol: MOB1C|MOB-LAK|moblak | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 126308 | HGNC ID: HGNC:29802 | Ensembl Gene: ENSG00000172081 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of MOB3A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MOB3A | 126308 | 225530_at | -0.1820 | 0.6676 | |
| GSE26886 | MOB3A | 126308 | 225530_at | 0.7179 | 0.0327 | |
| GSE45670 | MOB3A | 126308 | 225530_at | 0.2775 | 0.1473 | |
| GSE53622 | MOB3A | 126308 | 72519 | 0.1676 | 0.0318 | |
| GSE53624 | MOB3A | 126308 | 72519 | 0.4055 | 0.0000 | |
| GSE63941 | MOB3A | 126308 | 225530_at | -0.2796 | 0.5623 | |
| GSE77861 | MOB3A | 126308 | 225530_at | 0.6712 | 0.0807 | |
| GSE97050 | MOB3A | 126308 | A_23_P130919 | 0.6847 | 0.1095 | |
| SRP007169 | MOB3A | 126308 | RNAseq | 0.1193 | 0.7737 | |
| SRP008496 | MOB3A | 126308 | RNAseq | -0.0912 | 0.7107 | |
| SRP064894 | MOB3A | 126308 | RNAseq | 0.5368 | 0.0032 | |
| SRP133303 | MOB3A | 126308 | RNAseq | 0.0925 | 0.5255 | |
| SRP159526 | MOB3A | 126308 | RNAseq | -0.1557 | 0.6031 | |
| SRP193095 | MOB3A | 126308 | RNAseq | 0.5471 | 0.0002 | |
| SRP219564 | MOB3A | 126308 | RNAseq | -0.1323 | 0.6875 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MOB3A expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of MOB3A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MOB3A | 126308 | 4 | 6 | 20 | |
| GSE20123 | MOB3A | 126308 | 4 | 5 | 21 | |
| GSE43470 | MOB3A | 126308 | 1 | 10 | 32 | |
| GSE46452 | MOB3A | 126308 | 47 | 1 | 11 | |
| GSE47630 | MOB3A | 126308 | 5 | 7 | 28 | |
| GSE54993 | MOB3A | 126308 | 16 | 3 | 51 | |
| GSE54994 | MOB3A | 126308 | 8 | 15 | 30 | |
| GSE60625 | MOB3A | 126308 | 9 | 0 | 2 | |
| GSE74703 | MOB3A | 126308 | 1 | 7 | 28 | |
| GSE74704 | MOB3A | 126308 | 3 | 3 | 14 | |
| TCGA | MOB3A | 126308 | 7 | 24 | 65 |
Total number of gains: 105; Total number of losses: 81; Total Number of normals: 302.
Somatic mutations of MOB3A:
Generating mutation plots.
Highly correlated genes for MOB3A:
Showing top 20/447 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MOB3A | ANP32B | 0.807295 | 3 | 0 | 3 |
| MOB3A | WIPF1 | 0.78083 | 3 | 0 | 3 |
| MOB3A | TGFB1 | 0.766711 | 3 | 0 | 3 |
| MOB3A | FCGRT | 0.756111 | 3 | 0 | 3 |
| MOB3A | ADAR | 0.744794 | 3 | 0 | 3 |
| MOB3A | CTSB | 0.736994 | 3 | 0 | 3 |
| MOB3A | DAB2 | 0.733256 | 4 | 0 | 3 |
| MOB3A | STK32B | 0.730042 | 3 | 0 | 3 |
| MOB3A | FGFR1 | 0.72014 | 3 | 0 | 3 |
| MOB3A | NRM | 0.718064 | 4 | 0 | 4 |
| MOB3A | TAF6 | 0.715196 | 3 | 0 | 3 |
| MOB3A | SLFN11 | 0.703979 | 3 | 0 | 3 |
| MOB3A | SNRNP70 | 0.702049 | 3 | 0 | 3 |
| MOB3A | NFATC1 | 0.699547 | 3 | 0 | 3 |
| MOB3A | GNS | 0.699517 | 3 | 0 | 3 |
| MOB3A | PDGFB | 0.699329 | 4 | 0 | 4 |
| MOB3A | USP11 | 0.699279 | 3 | 0 | 3 |
| MOB3A | RHOBTB2 | 0.696485 | 3 | 0 | 3 |
| MOB3A | GLG1 | 0.696065 | 3 | 0 | 3 |
| MOB3A | S100PBP | 0.693954 | 3 | 0 | 3 |
For details and further investigation, click here
