| Full name: nuclear factor I B | Alias Symbol: NFI-RED|NFIB2|NFIB3 | ||
| Type: protein-coding gene | Cytoband: 9p23-p22.3 | ||
| Entrez ID: 4781 | HGNC ID: HGNC:7785 | Ensembl Gene: ENSG00000147862 | OMIM ID: 600728 |
| Drug and gene relationship at DGIdb | |||
Expression of NFIB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NFIB | 4781 | 209290_s_at | -0.7138 | 0.3529 | |
| GSE20347 | NFIB | 4781 | 209290_s_at | -0.0559 | 0.8046 | |
| GSE23400 | NFIB | 4781 | 209290_s_at | -0.2028 | 0.1409 | |
| GSE26886 | NFIB | 4781 | 209290_s_at | 1.2500 | 0.0017 | |
| GSE29001 | NFIB | 4781 | 209290_s_at | 0.1626 | 0.7885 | |
| GSE38129 | NFIB | 4781 | 209290_s_at | -0.3565 | 0.1269 | |
| GSE45670 | NFIB | 4781 | 209290_s_at | -1.2731 | 0.0001 | |
| GSE53622 | NFIB | 4781 | 44998 | -0.9553 | 0.0000 | |
| GSE53624 | NFIB | 4781 | 47971 | -0.7432 | 0.0000 | |
| GSE63941 | NFIB | 4781 | 209289_at | 4.7346 | 0.0003 | |
| GSE77861 | NFIB | 4781 | 209289_at | -0.0987 | 0.8486 | |
| GSE97050 | NFIB | 4781 | A_33_P3320079 | -0.3917 | 0.4145 | |
| SRP007169 | NFIB | 4781 | RNAseq | 1.3687 | 0.0278 | |
| SRP008496 | NFIB | 4781 | RNAseq | 1.5562 | 0.0001 | |
| SRP064894 | NFIB | 4781 | RNAseq | 0.0873 | 0.7628 | |
| SRP133303 | NFIB | 4781 | RNAseq | -0.7620 | 0.0054 | |
| SRP159526 | NFIB | 4781 | RNAseq | 0.6082 | 0.3181 | |
| SRP193095 | NFIB | 4781 | RNAseq | -0.5298 | 0.0007 | |
| SRP219564 | NFIB | 4781 | RNAseq | -0.4375 | 0.4934 | |
| TCGA | NFIB | 4781 | RNAseq | -0.3079 | 0.0010 |
Upregulated datasets: 4; Downregulated datasets: 1.
Survival by NFIB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NFIB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NFIB | 4781 | 2 | 15 | 13 | |
| GSE20123 | NFIB | 4781 | 2 | 15 | 13 | |
| GSE43470 | NFIB | 4781 | 5 | 11 | 27 | |
| GSE46452 | NFIB | 4781 | 2 | 23 | 34 | |
| GSE47630 | NFIB | 4781 | 4 | 26 | 10 | |
| GSE54993 | NFIB | 4781 | 6 | 3 | 61 | |
| GSE54994 | NFIB | 4781 | 10 | 16 | 27 | |
| GSE60625 | NFIB | 4781 | 0 | 0 | 11 | |
| GSE74703 | NFIB | 4781 | 5 | 8 | 23 | |
| GSE74704 | NFIB | 4781 | 0 | 12 | 8 | |
| TCGA | NFIB | 4781 | 14 | 52 | 30 |
Total number of gains: 50; Total number of losses: 181; Total Number of normals: 257.
Somatic mutations of NFIB:
Generating mutation plots.
Highly correlated genes for NFIB:
Showing top 20/350 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NFIB | UEVLD | 0.769205 | 3 | 0 | 3 |
| NFIB | ANP32B | 0.754771 | 3 | 0 | 3 |
| NFIB | AAAS | 0.753579 | 3 | 0 | 3 |
| NFIB | USP28 | 0.747134 | 3 | 0 | 3 |
| NFIB | C8orf37 | 0.742942 | 3 | 0 | 3 |
| NFIB | AFTPH | 0.730164 | 3 | 0 | 3 |
| NFIB | STARD3NL | 0.721168 | 3 | 0 | 3 |
| NFIB | ZNF566 | 0.718103 | 3 | 0 | 3 |
| NFIB | CD22 | 0.713722 | 3 | 0 | 3 |
| NFIB | RGS1 | 0.713522 | 3 | 0 | 3 |
| NFIB | CNTNAP3 | 0.712424 | 3 | 0 | 3 |
| NFIB | NHS | 0.709473 | 3 | 0 | 3 |
| NFIB | EPDR1 | 0.708905 | 4 | 0 | 4 |
| NFIB | EIF3M | 0.707291 | 3 | 0 | 3 |
| NFIB | CA11 | 0.702929 | 3 | 0 | 3 |
| NFIB | NOA1 | 0.701402 | 3 | 0 | 3 |
| NFIB | CYP1A2 | 0.699736 | 3 | 0 | 3 |
| NFIB | RPL14 | 0.695689 | 3 | 0 | 3 |
| NFIB | TAF4B | 0.694124 | 3 | 0 | 3 |
| NFIB | C11orf49 | 0.691733 | 4 | 0 | 4 |
For details and further investigation, click here
