| Full name: androgen receptor | Alias Symbol: AIS|NR3C4|SMAX1|HUMARA | ||
| Type: protein-coding gene | Cytoband: Xq12 | ||
| Entrez ID: 367 | HGNC ID: HGNC:644 | Ensembl Gene: ENSG00000169083 | OMIM ID: 313700 |
| Related drugs: (S,S)-FIDARESTAT, ABIRATERONE, APC-100, ARN-509, AZD3514, BICALUTAMIDE, BISPHENOL A, CB-03-01, CHEMBL125236, CHEMBL458084... [more] | |||
Screen Evidence:
| |||
AR involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04114 | Oocyte meiosis | |
| hsa05200 | Pathways in cancer | |
| hsa05215 | Prostate cancer |
Expression of AR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AR | 367 | 226192_at | -1.2970 | 0.0132 | |
| GSE20347 | AR | 367 | 211110_s_at | -0.2969 | 0.0009 | |
| GSE23400 | AR | 367 | 211110_s_at | -0.2605 | 0.0000 | |
| GSE26886 | AR | 367 | 226192_at | -1.4312 | 0.0004 | |
| GSE29001 | AR | 367 | 211621_at | -0.6645 | 0.0091 | |
| GSE38129 | AR | 367 | 211110_s_at | -0.6477 | 0.0000 | |
| GSE45670 | AR | 367 | 226192_at | -1.8938 | 0.0000 | |
| GSE53622 | AR | 367 | 74284 | -2.0813 | 0.0000 | |
| GSE53624 | AR | 367 | 74284 | -1.6710 | 0.0000 | |
| GSE63941 | AR | 367 | 226197_at | -2.2840 | 0.0038 | |
| GSE77861 | AR | 367 | 211110_s_at | -0.2076 | 0.0441 | |
| GSE97050 | AR | 367 | A_23_P113111 | -1.2340 | 0.1189 | |
| SRP007169 | AR | 367 | RNAseq | -2.8216 | 0.0000 | |
| SRP064894 | AR | 367 | RNAseq | -0.8727 | 0.0028 | |
| SRP133303 | AR | 367 | RNAseq | -1.1245 | 0.0000 | |
| SRP159526 | AR | 367 | RNAseq | -1.9153 | 0.0000 | |
| SRP193095 | AR | 367 | RNAseq | -1.0140 | 0.0000 | |
| SRP219564 | AR | 367 | RNAseq | -0.6178 | 0.0808 | |
| TCGA | AR | 367 | RNAseq | -1.7861 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 11.
Survival by AR expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AR:
No record found for this gene.
Somatic mutations of AR:
Generating mutation plots.
Highly correlated genes for AR:
Showing top 20/1507 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AR | C1QTNF7 | 0.821748 | 5 | 0 | 5 |
| AR | CLEC3B | 0.791715 | 3 | 0 | 3 |
| AR | NEGR1 | 0.785184 | 6 | 0 | 6 |
| AR | RGS7BP | 0.783282 | 5 | 0 | 5 |
| AR | CADM2 | 0.769753 | 3 | 0 | 3 |
| AR | ANGPTL1 | 0.767126 | 6 | 0 | 5 |
| AR | ZNF662 | 0.758936 | 7 | 0 | 7 |
| AR | SORCS1 | 0.757177 | 4 | 0 | 4 |
| AR | EIF4E3 | 0.753641 | 7 | 0 | 7 |
| AR | MYOCD | 0.751811 | 6 | 0 | 5 |
| AR | RBPMS2 | 0.749192 | 5 | 0 | 5 |
| AR | LINC01279 | 0.746795 | 3 | 0 | 3 |
| AR | MRVI1 | 0.74376 | 6 | 0 | 6 |
| AR | PARD3B | 0.742548 | 5 | 0 | 5 |
| AR | LRRK2 | 0.739419 | 8 | 0 | 8 |
| AR | NEXN | 0.738466 | 6 | 0 | 6 |
| AR | GPRASP2 | 0.731617 | 3 | 0 | 3 |
| AR | NFIA | 0.730632 | 7 | 0 | 7 |
| AR | ASPA | 0.727628 | 10 | 0 | 9 |
| AR | SH3BGRL2 | 0.727303 | 7 | 0 | 7 |
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