| Full name: glucosidase II alpha subunit | Alias Symbol: GluII|G2AN|KIAA0088|GIIA | ||
| Type: protein-coding gene | Cytoband: 11q12.3 | ||
| Entrez ID: 23193 | HGNC ID: HGNC:4138 | Ensembl Gene: ENSG00000089597 | OMIM ID: 104160 |
| Drug and gene relationship at DGIdb | |||
Expression of GANAB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GANAB | 23193 | 211934_x_at | 0.7419 | 0.0164 | |
| GSE20347 | GANAB | 23193 | 211934_x_at | 0.6277 | 0.0006 | |
| GSE23400 | GANAB | 23193 | 214626_s_at | 0.5722 | 0.0000 | |
| GSE26886 | GANAB | 23193 | 214626_s_at | 0.7353 | 0.0000 | |
| GSE29001 | GANAB | 23193 | 211934_x_at | 0.2527 | 0.3642 | |
| GSE38129 | GANAB | 23193 | 211934_x_at | 0.6625 | 0.0000 | |
| GSE45670 | GANAB | 23193 | 211934_x_at | 0.7706 | 0.0000 | |
| GSE53622 | GANAB | 23193 | 57692 | 0.4686 | 0.0000 | |
| GSE53624 | GANAB | 23193 | 57692 | 0.7468 | 0.0000 | |
| GSE63941 | GANAB | 23193 | 211934_x_at | 1.6543 | 0.0018 | |
| GSE77861 | GANAB | 23193 | 211934_x_at | 1.0538 | 0.0095 | |
| GSE97050 | GANAB | 23193 | A_23_P203406 | 0.3105 | 0.2436 | |
| SRP007169 | GANAB | 23193 | RNAseq | 2.0021 | 0.0000 | |
| SRP008496 | GANAB | 23193 | RNAseq | 1.8270 | 0.0000 | |
| SRP064894 | GANAB | 23193 | RNAseq | 0.8516 | 0.0000 | |
| SRP133303 | GANAB | 23193 | RNAseq | 0.6825 | 0.0002 | |
| SRP159526 | GANAB | 23193 | RNAseq | 1.0751 | 0.0000 | |
| SRP193095 | GANAB | 23193 | RNAseq | 0.5298 | 0.0001 | |
| SRP219564 | GANAB | 23193 | RNAseq | 0.7910 | 0.0312 | |
| TCGA | GANAB | 23193 | RNAseq | 0.0591 | 0.1122 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by GANAB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GANAB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GANAB | 23193 | 6 | 5 | 19 | |
| GSE20123 | GANAB | 23193 | 6 | 5 | 19 | |
| GSE43470 | GANAB | 23193 | 1 | 6 | 36 | |
| GSE46452 | GANAB | 23193 | 8 | 4 | 47 | |
| GSE47630 | GANAB | 23193 | 3 | 7 | 30 | |
| GSE54993 | GANAB | 23193 | 3 | 0 | 67 | |
| GSE54994 | GANAB | 23193 | 4 | 5 | 44 | |
| GSE60625 | GANAB | 23193 | 0 | 3 | 8 | |
| GSE74703 | GANAB | 23193 | 1 | 3 | 32 | |
| GSE74704 | GANAB | 23193 | 4 | 3 | 13 | |
| TCGA | GANAB | 23193 | 14 | 11 | 71 |
Total number of gains: 50; Total number of losses: 52; Total Number of normals: 386.
Somatic mutations of GANAB:
Generating mutation plots.
Highly correlated genes for GANAB:
Showing top 20/1884 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GANAB | SLC39A3 | 0.781423 | 4 | 0 | 4 |
| GANAB | NOTCH3 | 0.746735 | 4 | 0 | 4 |
| GANAB | CD276 | 0.745998 | 5 | 0 | 4 |
| GANAB | UBE2T | 0.744422 | 8 | 0 | 8 |
| GANAB | ARFRP1 | 0.744386 | 3 | 0 | 3 |
| GANAB | ZBTB9 | 0.7436 | 5 | 0 | 5 |
| GANAB | TMEM205 | 0.741798 | 3 | 0 | 3 |
| GANAB | ARAF | 0.73755 | 3 | 0 | 3 |
| GANAB | KLHDC3 | 0.735821 | 4 | 0 | 4 |
| GANAB | UCK2 | 0.734186 | 3 | 0 | 3 |
| GANAB | STPG1 | 0.730228 | 3 | 0 | 3 |
| GANAB | PIF1 | 0.727263 | 6 | 0 | 6 |
| GANAB | TSPAN17 | 0.72667 | 3 | 0 | 3 |
| GANAB | ZNF707 | 0.725953 | 3 | 0 | 3 |
| GANAB | TRAPPC1 | 0.725066 | 3 | 0 | 3 |
| GANAB | CIT | 0.724848 | 3 | 0 | 3 |
| GANAB | CKS1B | 0.724428 | 11 | 0 | 11 |
| GANAB | EARS2 | 0.723184 | 4 | 0 | 4 |
| GANAB | E2F7 | 0.723083 | 4 | 0 | 4 |
| GANAB | SORL1 | 0.722955 | 3 | 0 | 3 |
For details and further investigation, click here
