| Full name: dpy-19 like 4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 8q22.1 | ||
| Entrez ID: 286148 | HGNC ID: HGNC:27829 | Ensembl Gene: ENSG00000156162 | OMIM ID: 613895 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of DPY19L4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DPY19L4 | 286148 | 213391_at | 1.1078 | 0.0752 | |
| GSE20347 | DPY19L4 | 286148 | 213391_at | 1.3622 | 0.0000 | |
| GSE23400 | DPY19L4 | 286148 | 213391_at | 1.2158 | 0.0000 | |
| GSE26886 | DPY19L4 | 286148 | 213391_at | 1.5531 | 0.0000 | |
| GSE29001 | DPY19L4 | 286148 | 213391_at | 1.2331 | 0.0000 | |
| GSE38129 | DPY19L4 | 286148 | 213391_at | 1.1730 | 0.0000 | |
| GSE45670 | DPY19L4 | 286148 | 213391_at | 0.8288 | 0.0000 | |
| GSE53622 | DPY19L4 | 286148 | 30234 | 0.7222 | 0.0000 | |
| GSE53624 | DPY19L4 | 286148 | 30234 | 0.9182 | 0.0000 | |
| GSE63941 | DPY19L4 | 286148 | 213391_at | -0.3196 | 0.5027 | |
| GSE77861 | DPY19L4 | 286148 | 213391_at | 0.7704 | 0.0816 | |
| GSE97050 | DPY19L4 | 286148 | A_32_P196047 | 0.3935 | 0.1628 | |
| SRP007169 | DPY19L4 | 286148 | RNAseq | 0.8388 | 0.0327 | |
| SRP008496 | DPY19L4 | 286148 | RNAseq | 1.2965 | 0.0000 | |
| SRP064894 | DPY19L4 | 286148 | RNAseq | 1.0959 | 0.0001 | |
| SRP133303 | DPY19L4 | 286148 | RNAseq | 0.7486 | 0.0000 | |
| SRP159526 | DPY19L4 | 286148 | RNAseq | 0.4975 | 0.0015 | |
| SRP193095 | DPY19L4 | 286148 | RNAseq | 0.4035 | 0.0000 | |
| SRP219564 | DPY19L4 | 286148 | RNAseq | 0.5883 | 0.0557 | |
| TCGA | DPY19L4 | 286148 | RNAseq | -0.0877 | 0.1015 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by DPY19L4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DPY19L4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DPY19L4 | 286148 | 16 | 0 | 14 | |
| GSE20123 | DPY19L4 | 286148 | 17 | 0 | 13 | |
| GSE43470 | DPY19L4 | 286148 | 21 | 1 | 21 | |
| GSE46452 | DPY19L4 | 286148 | 23 | 0 | 36 | |
| GSE47630 | DPY19L4 | 286148 | 24 | 0 | 16 | |
| GSE54993 | DPY19L4 | 286148 | 0 | 20 | 50 | |
| GSE54994 | DPY19L4 | 286148 | 34 | 1 | 18 | |
| GSE60625 | DPY19L4 | 286148 | 0 | 4 | 7 | |
| GSE74703 | DPY19L4 | 286148 | 18 | 1 | 17 | |
| GSE74704 | DPY19L4 | 286148 | 12 | 0 | 8 | |
| TCGA | DPY19L4 | 286148 | 56 | 1 | 39 |
Total number of gains: 221; Total number of losses: 28; Total Number of normals: 239.
Somatic mutations of DPY19L4:
Generating mutation plots.
Highly correlated genes for DPY19L4:
Showing top 20/2253 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DPY19L4 | MTERF3 | 0.806645 | 9 | 0 | 8 |
| DPY19L4 | ENY2 | 0.792969 | 12 | 0 | 12 |
| DPY19L4 | LAPTM4B | 0.789682 | 12 | 0 | 11 |
| DPY19L4 | SLC25A32 | 0.78043 | 12 | 0 | 12 |
| DPY19L4 | RAD21 | 0.779771 | 10 | 0 | 10 |
| DPY19L4 | STK3 | 0.760553 | 13 | 0 | 12 |
| DPY19L4 | TAF2 | 0.759609 | 12 | 0 | 11 |
| DPY19L4 | ZNF451 | 0.759403 | 4 | 0 | 4 |
| DPY19L4 | ATP6V1C1 | 0.755155 | 12 | 0 | 11 |
| DPY19L4 | PDE7A | 0.75501 | 7 | 0 | 7 |
| DPY19L4 | ARHGAP24 | 0.749667 | 3 | 0 | 3 |
| DPY19L4 | ATAD2 | 0.746513 | 12 | 0 | 12 |
| DPY19L4 | NUDCD1 | 0.746057 | 8 | 0 | 7 |
| DPY19L4 | TBC1D31 | 0.745942 | 10 | 0 | 10 |
| DPY19L4 | FZD6 | 0.745446 | 11 | 0 | 10 |
| DPY19L4 | PTK2 | 0.744404 | 12 | 0 | 11 |
| DPY19L4 | PKIG | 0.744299 | 3 | 0 | 3 |
| DPY19L4 | IPO9 | 0.74245 | 8 | 0 | 8 |
| DPY19L4 | C8orf82 | 0.742153 | 3 | 0 | 3 |
| DPY19L4 | CBX3 | 0.740815 | 10 | 0 | 10 |
For details and further investigation, click here
