| Full name: alanyl aminopeptidase, membrane | Alias Symbol: LAP1|gp150|p150 | ||
| Type: protein-coding gene | Cytoband: 15q26.1 | ||
| Entrez ID: 290 | HGNC ID: HGNC:500 | Ensembl Gene: ENSG00000166825 | OMIM ID: 151530 |
| Drug and gene relationship at DGIdb | |||
Expression of ANPEP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANPEP | 290 | 202888_s_at | 0.3243 | 0.7528 | |
| GSE20347 | ANPEP | 290 | 202888_s_at | 0.4069 | 0.0067 | |
| GSE23400 | ANPEP | 290 | 202888_s_at | 0.0759 | 0.0321 | |
| GSE26886 | ANPEP | 290 | 202888_s_at | 0.9566 | 0.0176 | |
| GSE29001 | ANPEP | 290 | 202888_s_at | 0.1791 | 0.1953 | |
| GSE38129 | ANPEP | 290 | 202888_s_at | 0.4839 | 0.0154 | |
| GSE45670 | ANPEP | 290 | 202888_s_at | 0.4878 | 0.1037 | |
| GSE53622 | ANPEP | 290 | 24420 | 0.6752 | 0.0001 | |
| GSE53624 | ANPEP | 290 | 24420 | 0.7005 | 0.0000 | |
| GSE63941 | ANPEP | 290 | 202888_s_at | -3.1290 | 0.0006 | |
| GSE77861 | ANPEP | 290 | 202888_s_at | 0.1563 | 0.0713 | |
| GSE97050 | ANPEP | 290 | A_23_P88626 | 0.7115 | 0.1716 | |
| SRP007169 | ANPEP | 290 | RNAseq | 3.5099 | 0.0001 | |
| SRP064894 | ANPEP | 290 | RNAseq | 1.3586 | 0.0004 | |
| SRP133303 | ANPEP | 290 | RNAseq | 0.9116 | 0.0022 | |
| SRP159526 | ANPEP | 290 | RNAseq | 0.1732 | 0.6754 | |
| SRP193095 | ANPEP | 290 | RNAseq | -0.8560 | 0.1357 | |
| SRP219564 | ANPEP | 290 | RNAseq | 1.1975 | 0.0184 | |
| TCGA | ANPEP | 290 | RNAseq | 0.5066 | 0.0011 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by ANPEP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANPEP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANPEP | 290 | 8 | 3 | 19 | |
| GSE20123 | ANPEP | 290 | 8 | 3 | 19 | |
| GSE43470 | ANPEP | 290 | 5 | 4 | 34 | |
| GSE46452 | ANPEP | 290 | 3 | 7 | 49 | |
| GSE47630 | ANPEP | 290 | 8 | 11 | 21 | |
| GSE54993 | ANPEP | 290 | 4 | 6 | 60 | |
| GSE54994 | ANPEP | 290 | 7 | 6 | 40 | |
| GSE60625 | ANPEP | 290 | 4 | 0 | 7 | |
| GSE74703 | ANPEP | 290 | 4 | 3 | 29 | |
| GSE74704 | ANPEP | 290 | 4 | 2 | 14 | |
| TCGA | ANPEP | 290 | 17 | 12 | 67 |
Total number of gains: 72; Total number of losses: 57; Total Number of normals: 359.
Somatic mutations of ANPEP:
Generating mutation plots.
Highly correlated genes for ANPEP:
Showing top 20/749 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANPEP | MRGPRF | 0.805166 | 3 | 0 | 3 |
| ANPEP | ARHGAP24 | 0.800473 | 4 | 0 | 4 |
| ANPEP | LRRN4CL | 0.787053 | 3 | 0 | 3 |
| ANPEP | DDIT3 | 0.778084 | 3 | 0 | 3 |
| ANPEP | C11orf96 | 0.775076 | 3 | 0 | 3 |
| ANPEP | RPS27L | 0.770314 | 3 | 0 | 3 |
| ANPEP | KCNJ2 | 0.763928 | 3 | 0 | 3 |
| ANPEP | ABHD16B | 0.74888 | 3 | 0 | 3 |
| ANPEP | PRKG1 | 0.744052 | 3 | 0 | 3 |
| ANPEP | RNF145 | 0.737141 | 3 | 0 | 3 |
| ANPEP | EGLN2 | 0.736854 | 3 | 0 | 3 |
| ANPEP | HMCN1 | 0.734698 | 3 | 0 | 3 |
| ANPEP | SGTB | 0.734286 | 3 | 0 | 3 |
| ANPEP | GNG2 | 0.730179 | 3 | 0 | 3 |
| ANPEP | TMX3 | 0.729896 | 3 | 0 | 3 |
| ANPEP | MGAT5 | 0.727869 | 5 | 0 | 4 |
| ANPEP | A2M | 0.726234 | 3 | 0 | 3 |
| ANPEP | CTRB2 | 0.723909 | 3 | 0 | 3 |
| ANPEP | DERL3 | 0.722892 | 4 | 0 | 4 |
| ANPEP | CCDC80 | 0.72152 | 3 | 0 | 3 |
For details and further investigation, click here
