| Full name: migration and invasion enhancer 1 | Alias Symbol: MGC14832|ORB3|XTP4|C35|Rdx12 | ||
| Type: protein-coding gene | Cytoband: 17q12 | ||
| Entrez ID: 84299 | HGNC ID: HGNC:28230 | Ensembl Gene: ENSG00000141741 | OMIM ID: 611802 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of MIEN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MIEN1 | 84299 | 224447_s_at | 0.0460 | 0.9655 | |
| GSE26886 | MIEN1 | 84299 | 224447_s_at | 0.8061 | 0.0008 | |
| GSE45670 | MIEN1 | 84299 | 224447_s_at | 0.1440 | 0.6121 | |
| GSE53622 | MIEN1 | 84299 | 57775 | 0.0419 | 0.6873 | |
| GSE53624 | MIEN1 | 84299 | 57775 | 0.0079 | 0.8989 | |
| GSE63941 | MIEN1 | 84299 | 224447_s_at | 1.0717 | 0.1845 | |
| GSE77861 | MIEN1 | 84299 | 224447_s_at | 0.3696 | 0.1842 | |
| GSE97050 | MIEN1 | 84299 | A_23_P3982 | 0.2899 | 0.3501 | |
| SRP007169 | MIEN1 | 84299 | RNAseq | 0.4455 | 0.5185 | |
| SRP008496 | MIEN1 | 84299 | RNAseq | -0.8465 | 0.0003 | |
| SRP064894 | MIEN1 | 84299 | RNAseq | -0.1140 | 0.7286 | |
| SRP133303 | MIEN1 | 84299 | RNAseq | -0.0530 | 0.7362 | |
| SRP159526 | MIEN1 | 84299 | RNAseq | -0.2110 | 0.4875 | |
| SRP193095 | MIEN1 | 84299 | RNAseq | -0.2997 | 0.0139 | |
| SRP219564 | MIEN1 | 84299 | RNAseq | -0.3515 | 0.2622 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MIEN1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of MIEN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MIEN1 | 84299 | 9 | 1 | 20 | |
| GSE20123 | MIEN1 | 84299 | 9 | 1 | 20 | |
| GSE43470 | MIEN1 | 84299 | 1 | 1 | 41 | |
| GSE46452 | MIEN1 | 84299 | 34 | 0 | 25 | |
| GSE47630 | MIEN1 | 84299 | 8 | 1 | 31 | |
| GSE54993 | MIEN1 | 84299 | 3 | 4 | 63 | |
| GSE54994 | MIEN1 | 84299 | 9 | 5 | 39 | |
| GSE60625 | MIEN1 | 84299 | 4 | 0 | 7 | |
| GSE74703 | MIEN1 | 84299 | 1 | 0 | 35 | |
| GSE74704 | MIEN1 | 84299 | 5 | 1 | 14 | |
| TCGA | MIEN1 | 84299 | 23 | 8 | 65 |
Total number of gains: 106; Total number of losses: 22; Total Number of normals: 360.
Somatic mutations of MIEN1:
Generating mutation plots.
Highly correlated genes for MIEN1:
Showing top 20/327 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MIEN1 | ARHGAP24 | 0.777095 | 3 | 0 | 3 |
| MIEN1 | RPS6KA3 | 0.763092 | 3 | 0 | 3 |
| MIEN1 | DAZAP1 | 0.75972 | 3 | 0 | 3 |
| MIEN1 | THADA | 0.755299 | 3 | 0 | 3 |
| MIEN1 | COLEC11 | 0.744849 | 3 | 0 | 3 |
| MIEN1 | RRS1 | 0.743318 | 3 | 0 | 3 |
| MIEN1 | HEATR1 | 0.728624 | 3 | 0 | 3 |
| MIEN1 | DHRS13 | 0.726428 | 4 | 0 | 4 |
| MIEN1 | POLA1 | 0.724231 | 3 | 0 | 3 |
| MIEN1 | MRPL38 | 0.719747 | 3 | 0 | 3 |
| MIEN1 | PTGES3 | 0.716802 | 3 | 0 | 3 |
| MIEN1 | DGUOK | 0.715784 | 3 | 0 | 3 |
| MIEN1 | PIK3R3 | 0.715716 | 4 | 0 | 4 |
| MIEN1 | SMYD3 | 0.714465 | 3 | 0 | 3 |
| MIEN1 | AHCTF1 | 0.714355 | 3 | 0 | 3 |
| MIEN1 | ABCF1 | 0.712456 | 3 | 0 | 3 |
| MIEN1 | NUP43 | 0.707271 | 3 | 0 | 3 |
| MIEN1 | MSTO1 | 0.705713 | 3 | 0 | 3 |
| MIEN1 | MAGOHB | 0.705697 | 3 | 0 | 3 |
| MIEN1 | INHBB | 0.705478 | 3 | 0 | 3 |
For details and further investigation, click here
