| Full name: Rho GTPase activating protein 25 | Alias Symbol: KIAA0053 | ||
| Type: protein-coding gene | Cytoband: 2p13.3 | ||
| Entrez ID: 9938 | HGNC ID: HGNC:28951 | Ensembl Gene: ENSG00000163219 | OMIM ID: 610587 |
| Drug and gene relationship at DGIdb | |||
Expression of ARHGAP25:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARHGAP25 | 9938 | 204882_at | 0.1429 | 0.8581 | |
| GSE20347 | ARHGAP25 | 9938 | 204882_at | 0.3263 | 0.0585 | |
| GSE23400 | ARHGAP25 | 9938 | 204882_at | 0.0579 | 0.2819 | |
| GSE26886 | ARHGAP25 | 9938 | 204882_at | 0.0931 | 0.7667 | |
| GSE29001 | ARHGAP25 | 9938 | 204882_at | 0.0918 | 0.6481 | |
| GSE38129 | ARHGAP25 | 9938 | 204882_at | 0.1397 | 0.4366 | |
| GSE45670 | ARHGAP25 | 9938 | 204882_at | -0.0836 | 0.7481 | |
| GSE53622 | ARHGAP25 | 9938 | 38459 | -0.0825 | 0.3386 | |
| GSE53624 | ARHGAP25 | 9938 | 84539 | 0.2770 | 0.0060 | |
| GSE63941 | ARHGAP25 | 9938 | 38149_at | 0.2728 | 0.2219 | |
| GSE77861 | ARHGAP25 | 9938 | 38149_at | -0.0760 | 0.6203 | |
| GSE97050 | ARHGAP25 | 9938 | A_23_P142974 | 0.6535 | 0.1623 | |
| SRP007169 | ARHGAP25 | 9938 | RNAseq | 1.5036 | 0.0894 | |
| SRP064894 | ARHGAP25 | 9938 | RNAseq | 0.4116 | 0.0215 | |
| SRP133303 | ARHGAP25 | 9938 | RNAseq | -0.1323 | 0.5888 | |
| SRP159526 | ARHGAP25 | 9938 | RNAseq | -0.1190 | 0.8050 | |
| SRP193095 | ARHGAP25 | 9938 | RNAseq | 0.5331 | 0.0108 | |
| SRP219564 | ARHGAP25 | 9938 | RNAseq | 0.3843 | 0.3306 | |
| TCGA | ARHGAP25 | 9938 | RNAseq | 0.2436 | 0.0375 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ARHGAP25 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARHGAP25:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARHGAP25 | 9938 | 11 | 0 | 19 | |
| GSE20123 | ARHGAP25 | 9938 | 11 | 0 | 19 | |
| GSE43470 | ARHGAP25 | 9938 | 6 | 0 | 37 | |
| GSE46452 | ARHGAP25 | 9938 | 2 | 3 | 54 | |
| GSE47630 | ARHGAP25 | 9938 | 7 | 0 | 33 | |
| GSE54993 | ARHGAP25 | 9938 | 0 | 6 | 64 | |
| GSE54994 | ARHGAP25 | 9938 | 12 | 0 | 41 | |
| GSE60625 | ARHGAP25 | 9938 | 0 | 3 | 8 | |
| GSE74703 | ARHGAP25 | 9938 | 6 | 0 | 30 | |
| GSE74704 | ARHGAP25 | 9938 | 9 | 0 | 11 | |
| TCGA | ARHGAP25 | 9938 | 36 | 2 | 58 |
Total number of gains: 100; Total number of losses: 14; Total Number of normals: 374.
Somatic mutations of ARHGAP25:
Generating mutation plots.
Highly correlated genes for ARHGAP25:
Showing top 20/254 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARHGAP25 | FAM78A | 0.702359 | 3 | 0 | 3 |
| ARHGAP25 | TRAT1 | 0.670088 | 7 | 0 | 7 |
| ARHGAP25 | GIMAP2 | 0.662721 | 7 | 0 | 6 |
| ARHGAP25 | SASH3 | 0.652605 | 12 | 0 | 10 |
| ARHGAP25 | ZBTB32 | 0.647844 | 3 | 0 | 3 |
| ARHGAP25 | ITGA4 | 0.644058 | 5 | 0 | 4 |
| ARHGAP25 | CD53 | 0.638367 | 10 | 0 | 9 |
| ARHGAP25 | ADAM28 | 0.635881 | 6 | 0 | 4 |
| ARHGAP25 | GJD3 | 0.634689 | 4 | 0 | 3 |
| ARHGAP25 | CSF2RB | 0.631985 | 9 | 0 | 7 |
| ARHGAP25 | CORO1A | 0.630988 | 11 | 0 | 9 |
| ARHGAP25 | IL2RB | 0.63053 | 10 | 0 | 8 |
| ARHGAP25 | TYK2 | 0.630412 | 3 | 0 | 3 |
| ARHGAP25 | GZMK | 0.623368 | 7 | 0 | 5 |
| ARHGAP25 | PSMB8-AS1 | 0.620672 | 5 | 0 | 4 |
| ARHGAP25 | P2RY8 | 0.619585 | 5 | 0 | 3 |
| ARHGAP25 | COL9A2 | 0.619133 | 3 | 0 | 3 |
| ARHGAP25 | EVI2A | 0.618936 | 8 | 0 | 7 |
| ARHGAP25 | HLA-DMB | 0.618923 | 11 | 0 | 8 |
| ARHGAP25 | SLAMF6 | 0.618244 | 6 | 0 | 5 |
For details and further investigation, click here
