LRRC17

 

Full name: leucine rich repeat containing 17 Alias Symbol: P37NB|H_RG318M05.3
Type: protein-coding gene Cytoband: 7q22.1
Entrez ID: 10234 HGNC ID: HGNC:16895 Ensembl Gene: ENSG00000128606 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of LRRC17:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 LRRC17 10234 205381_at 0.6459 0.6416
GSE20347 LRRC17 10234 205381_at 1.0977 0.0023
GSE23400 LRRC17 10234 205381_at 0.4073 0.0145
GSE26886 LRRC17 10234 205381_at 1.6883 0.0002
GSE29001 LRRC17 10234 205381_at 0.6367 0.0397
GSE38129 LRRC17 10234 205381_at 0.4942 0.2714
GSE45670 LRRC17 10234 205381_at -1.6190 0.0077
GSE53622 LRRC17 10234 69472 1.2230 0.0000
GSE53624 LRRC17 10234 69472 1.5646 0.0000
GSE63941 LRRC17 10234 205381_at -5.7686 0.0002
GSE77861 LRRC17 10234 205381_at 0.1290 0.5310
GSE97050 LRRC17 10234 A_23_P253958 0.3489 0.3024
SRP007169 LRRC17 10234 RNAseq 3.8582 0.0000
SRP064894 LRRC17 10234 RNAseq 1.7260 0.0002
SRP133303 LRRC17 10234 RNAseq 1.8130 0.0002
SRP159526 LRRC17 10234 RNAseq -0.2828 0.6588
SRP219564 LRRC17 10234 RNAseq 1.9309 0.0078
TCGA LRRC17 10234 RNAseq -0.4051 0.0822

Upregulated datasets: 8; Downregulated datasets: 2.  

 

Survival by LRRC17 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of LRRC17:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 LRRC17 10234 13 0 17
GSE20123 LRRC17 10234 13 0 17
GSE43470 LRRC17 10234 6 2 35
GSE46452 LRRC17 10234 10 1 48
GSE47630 LRRC17 10234 7 3 30
GSE54993 LRRC17 10234 1 10 59
GSE54994 LRRC17 10234 15 3 35
GSE60625 LRRC17 10234 0 0 11
GSE74703 LRRC17 10234 6 2 28
GSE74704 LRRC17 10234 9 0 11
TCGA LRRC17 10234 53 6 37

Total number of gains: 133; Total number of losses: 27; Total Number of normals: 328.  

 

Somatic mutations of LRRC17:

 

Generating mutation plots.

 

Highly correlated genes for LRRC17:

 

Showing top 20/1050 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
LRRC17ISLR0.77368412012
LRRC17ARHGAP310.767852303
LRRC17STOML10.757197303
LRRC17LACTB0.749236303
LRRC17GDF60.745346303
LRRC17FBN10.74258911011
LRRC17C11orf960.741569404
LRRC17COL8A10.74022810010
LRRC17S1PR10.735486404
LRRC17TMX30.735201303
LRRC17CTSK0.73518113013
LRRC17PCOLCE0.7309813012
LRRC17ANGPTL20.72969112011
LRRC17EFEMP20.72619912011
LRRC17SCYL10.717515303
LRRC17GDF110.713909303
LRRC17DACT10.71272913013
LRRC17COL6A10.71110413012
LRRC17PDGFRB0.71021112011
LRRC17CPT1C0.708999403

For details and further investigation, click here