| Full name: Rho guanine nucleotide exchange factor 19 | Alias Symbol: FLJ33962|WGEF | ||
| Type: protein-coding gene | Cytoband: 1p36.13 | ||
| Entrez ID: 128272 | HGNC ID: HGNC:26604 | Ensembl Gene: ENSG00000142632 | OMIM ID: 612496 |
| Drug and gene relationship at DGIdb | |||
Expression of ARHGEF19:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARHGEF19 | 128272 | 226857_at | 0.5175 | 0.0386 | |
| GSE26886 | ARHGEF19 | 128272 | 226857_at | 0.3848 | 0.0214 | |
| GSE45670 | ARHGEF19 | 128272 | 226857_at | 0.5417 | 0.0001 | |
| GSE53622 | ARHGEF19 | 128272 | 86966 | 0.7166 | 0.0000 | |
| GSE53624 | ARHGEF19 | 128272 | 86966 | 0.4618 | 0.0000 | |
| GSE63941 | ARHGEF19 | 128272 | 226857_at | 1.2166 | 0.0181 | |
| GSE77861 | ARHGEF19 | 128272 | 226857_at | 0.0087 | 0.9774 | |
| GSE97050 | ARHGEF19 | 128272 | A_33_P3315342 | 0.1404 | 0.8793 | |
| SRP007169 | ARHGEF19 | 128272 | RNAseq | -0.7296 | 0.1371 | |
| SRP008496 | ARHGEF19 | 128272 | RNAseq | -1.0010 | 0.0014 | |
| SRP064894 | ARHGEF19 | 128272 | RNAseq | 0.5064 | 0.0447 | |
| SRP133303 | ARHGEF19 | 128272 | RNAseq | 0.1481 | 0.5882 | |
| SRP193095 | ARHGEF19 | 128272 | RNAseq | 0.3965 | 0.1017 | |
| SRP219564 | ARHGEF19 | 128272 | RNAseq | -0.1948 | 0.7370 | |
| TCGA | ARHGEF19 | 128272 | RNAseq | 0.4371 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by ARHGEF19 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARHGEF19:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARHGEF19 | 128272 | 1 | 5 | 24 | |
| GSE20123 | ARHGEF19 | 128272 | 1 | 4 | 25 | |
| GSE43470 | ARHGEF19 | 128272 | 1 | 8 | 34 | |
| GSE46452 | ARHGEF19 | 128272 | 7 | 1 | 51 | |
| GSE47630 | ARHGEF19 | 128272 | 8 | 3 | 29 | |
| GSE54993 | ARHGEF19 | 128272 | 3 | 1 | 66 | |
| GSE54994 | ARHGEF19 | 128272 | 10 | 5 | 38 | |
| GSE60625 | ARHGEF19 | 128272 | 0 | 0 | 11 | |
| GSE74703 | ARHGEF19 | 128272 | 1 | 5 | 30 | |
| GSE74704 | ARHGEF19 | 128272 | 1 | 0 | 19 | |
| TCGA | ARHGEF19 | 128272 | 11 | 23 | 62 |
Total number of gains: 44; Total number of losses: 55; Total Number of normals: 389.
Somatic mutations of ARHGEF19:
Generating mutation plots.
Highly correlated genes for ARHGEF19:
Showing top 20/899 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARHGEF19 | PPAT | 0.814309 | 3 | 0 | 3 |
| ARHGEF19 | TMEM11 | 0.792197 | 3 | 0 | 3 |
| ARHGEF19 | FASTKD1 | 0.791452 | 3 | 0 | 3 |
| ARHGEF19 | RNF187 | 0.788967 | 3 | 0 | 3 |
| ARHGEF19 | IFRD2 | 0.7837 | 3 | 0 | 3 |
| ARHGEF19 | ACVR1C | 0.767551 | 3 | 0 | 3 |
| ARHGEF19 | GEN1 | 0.762499 | 4 | 0 | 4 |
| ARHGEF19 | SLC25A1 | 0.761384 | 3 | 0 | 3 |
| ARHGEF19 | GPR158 | 0.758926 | 3 | 0 | 3 |
| ARHGEF19 | SPSB2 | 0.749158 | 3 | 0 | 3 |
| ARHGEF19 | SLC25A39 | 0.744741 | 3 | 0 | 3 |
| ARHGEF19 | GGH | 0.73606 | 3 | 0 | 3 |
| ARHGEF19 | DCAF13 | 0.734788 | 3 | 0 | 3 |
| ARHGEF19 | EPN1 | 0.733211 | 3 | 0 | 3 |
| ARHGEF19 | MSH2 | 0.730009 | 4 | 0 | 4 |
| ARHGEF19 | ZNHIT2 | 0.72941 | 4 | 0 | 4 |
| ARHGEF19 | WDR5 | 0.727903 | 3 | 0 | 3 |
| ARHGEF19 | RBM12B | 0.727497 | 3 | 0 | 3 |
| ARHGEF19 | ATAD5 | 0.725032 | 4 | 0 | 4 |
| ARHGEF19 | PDCD2L | 0.724173 | 4 | 0 | 4 |
For details and further investigation, click here
