ATAD5

 

Full name: ATPase family AAA domain containing 5 Alias Symbol: FLJ12735|FRAG1|ELG1
Type: protein-coding gene Cytoband: 17q11.2
Entrez ID: 79915 HGNC ID: HGNC:25752 Ensembl Gene: ENSG00000176208 OMIM ID: 609534
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of ATAD5:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ATAD5 79915 220223_at 0.5763 0.0502
GSE20347 ATAD5 79915 220223_at 0.3876 0.0001
GSE23400 ATAD5 79915 220223_at 0.1915 0.0000
GSE26886 ATAD5 79915 220223_at 0.2965 0.0552
GSE29001 ATAD5 79915 220223_at 0.4301 0.0487
GSE38129 ATAD5 79915 220223_at 0.6398 0.0000
GSE45670 ATAD5 79915 220223_at 0.5580 0.0052
GSE53622 ATAD5 79915 27423 0.8392 0.0000
GSE53624 ATAD5 79915 27423 1.0527 0.0000
GSE63941 ATAD5 79915 220223_at 1.1569 0.0047
GSE77861 ATAD5 79915 220223_at 0.2068 0.1376
GSE97050 ATAD5 79915 A_24_P113144 0.3041 0.3143
SRP007169 ATAD5 79915 RNAseq 2.0146 0.0000
SRP008496 ATAD5 79915 RNAseq 1.6821 0.0000
SRP064894 ATAD5 79915 RNAseq 0.6163 0.0535
SRP133303 ATAD5 79915 RNAseq 1.0415 0.0000
SRP159526 ATAD5 79915 RNAseq 1.0472 0.0006
SRP193095 ATAD5 79915 RNAseq 0.7543 0.0000
SRP219564 ATAD5 79915 RNAseq 0.6375 0.1801
TCGA ATAD5 79915 RNAseq 0.7713 0.0000

Upregulated datasets: 6; Downregulated datasets: 0.  

 

Survival by ATAD5 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of ATAD5:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ATAD5 79915 8 2 20
GSE20123 ATAD5 79915 9 2 19
GSE43470 ATAD5 79915 0 1 42
GSE46452 ATAD5 79915 33 1 25
GSE47630 ATAD5 79915 7 1 32
GSE54993 ATAD5 79915 2 3 65
GSE54994 ATAD5 79915 7 6 40
GSE60625 ATAD5 79915 4 0 7
GSE74703 ATAD5 79915 0 1 35
GSE74704 ATAD5 79915 6 2 12
TCGA ATAD5 79915 19 11 66

Total number of gains: 95; Total number of losses: 30; Total Number of normals: 363.  

 

Somatic mutations of ATAD5:

 

Generating mutation plots.

 

Highly correlated genes for ATAD5:

 

Showing top 20/1308 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ATAD5SPSB20.791257303
ATAD5CBL0.790563303
ATAD5RNF1870.772079303
ATAD5TMEM63B0.765666303
ATAD5NFKBID0.765428303
ATAD5MMS22L0.758987303
ATAD5LTBR0.751374303
ATAD5UCK20.74457303
ATAD5RTN4IP10.739154303
ATAD5ZBTB90.737508505
ATAD5MMP150.735809303
ATAD5MCM80.725879707
ATAD5MRPL380.725737303
ATAD5ARHGEF190.725032404
ATAD5CDCA20.722004505
ATAD5LRIF10.715843303
ATAD5KNTC10.71397411010
ATAD5KIF18B0.71287909
ATAD5SLC39A10.706134404
ATAD5TTK0.70477511011

For details and further investigation, click here