IMPG1

 

Full name: interphotoreceptor matrix proteoglycan 1 Alias Symbol: IPM150|GP147
Type: protein-coding gene Cytoband: 6q14.1
Entrez ID: 3617 HGNC ID: HGNC:6055 Ensembl Gene: ENSG00000112706 OMIM ID: 602870
Drug and gene relationship at DGIdb

 

Expression of IMPG1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 IMPG1 3617 207054_at -0.0546 0.8184
GSE20347 IMPG1 3617 207054_at -0.0101 0.8630
GSE23400 IMPG1 3617 207054_at -0.0054 0.7610
GSE26886 IMPG1 3617 207054_at 0.1020 0.1708
GSE29001 IMPG1 3617 207054_at -0.0197 0.8447
GSE38129 IMPG1 3617 207054_at -0.0667 0.0936
GSE45670 IMPG1 3617 207054_at -0.1141 0.1073
GSE53622 IMPG1 3617 25330 0.4319 0.0045
GSE53624 IMPG1 3617 86422 -0.4148 0.0003
GSE63941 IMPG1 3617 207054_at -0.0287 0.8044
GSE77861 IMPG1 3617 207054_at -0.1142 0.2224
SRP133303 IMPG1 3617 RNAseq 0.3535 0.2885
SRP159526 IMPG1 3617 RNAseq -0.9942 0.2166
TCGA IMPG1 3617 RNAseq -0.7058 0.0574

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by IMPG1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of IMPG1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 IMPG1 3617 1 3 26
GSE20123 IMPG1 3617 1 2 27
GSE43470 IMPG1 3617 2 0 41
GSE46452 IMPG1 3617 2 11 46
GSE47630 IMPG1 3617 8 4 28
GSE54993 IMPG1 3617 3 2 65
GSE54994 IMPG1 3617 8 6 39
GSE60625 IMPG1 3617 0 1 10
GSE74703 IMPG1 3617 2 0 34
GSE74704 IMPG1 3617 0 1 19
TCGA IMPG1 3617 10 19 67

Total number of gains: 37; Total number of losses: 49; Total Number of normals: 402.  


 

Somatic mutations of IMPG1:

 

Generating mutation plots.

 

Highly correlated genes for IMPG1:

 

Showing top 20/148 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
IMPG1ARHGEF380.682012303
IMPG1CLCN40.662322404
IMPG1SLC5A40.658924303
IMPG1OR2J20.658094303
IMPG1CA80.646174403
IMPG1KIF5A0.625493303
IMPG1GRM50.616584303
IMPG1CRYBA10.609714303
IMPG1GPR220.605428303
IMPG1HAVCR10.600407303
IMPG1HTR1D0.594575303
IMPG1CRLF20.593274303
IMPG1PLEKHF10.585813403
IMPG1TAAR50.584635604
IMPG1ALAS20.580639403
IMPG1TAS2R90.58043403
IMPG1DRD20.576751403
IMPG1ELSPBP10.576454503
IMPG1OR5I10.576177403
IMPG1GCM10.575597403

For details and further investigation, click here