| Full name: ADP ribosylation factor like GTPase 6 interacting protein 5 | Alias Symbol: PRAF3|JWA|GTRAP3-18|DERP11|HSPC127|Yip6b | ||
| Type: protein-coding gene | Cytoband: 3p14.1 | ||
| Entrez ID: 10550 | HGNC ID: HGNC:16937 | Ensembl Gene: ENSG00000144746 | OMIM ID: 605709 |
| Drug and gene relationship at DGIdb | |||
Expression of ARL6IP5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARL6IP5 | 10550 | 200761_s_at | -0.9231 | 0.0167 | |
| GSE20347 | ARL6IP5 | 10550 | 200761_s_at | -1.3643 | 0.0000 | |
| GSE23400 | ARL6IP5 | 10550 | 200761_s_at | -0.6324 | 0.0000 | |
| GSE26886 | ARL6IP5 | 10550 | 200761_s_at | -1.1509 | 0.0002 | |
| GSE29001 | ARL6IP5 | 10550 | 200761_s_at | -0.8201 | 0.0052 | |
| GSE38129 | ARL6IP5 | 10550 | 200761_s_at | -1.3056 | 0.0000 | |
| GSE45670 | ARL6IP5 | 10550 | 200761_s_at | -0.8666 | 0.0014 | |
| GSE53622 | ARL6IP5 | 10550 | 84325 | -0.8052 | 0.0000 | |
| GSE53624 | ARL6IP5 | 10550 | 84325 | -0.8020 | 0.0000 | |
| GSE63941 | ARL6IP5 | 10550 | 200761_s_at | -1.7648 | 0.0051 | |
| GSE77861 | ARL6IP5 | 10550 | 200761_s_at | -1.2008 | 0.0006 | |
| GSE97050 | ARL6IP5 | 10550 | A_24_P257348 | -0.5377 | 0.0815 | |
| SRP007169 | ARL6IP5 | 10550 | RNAseq | -1.2976 | 0.0034 | |
| SRP008496 | ARL6IP5 | 10550 | RNAseq | -0.7844 | 0.0150 | |
| SRP064894 | ARL6IP5 | 10550 | RNAseq | -0.4121 | 0.0763 | |
| SRP133303 | ARL6IP5 | 10550 | RNAseq | -0.3873 | 0.0489 | |
| SRP159526 | ARL6IP5 | 10550 | RNAseq | -0.8709 | 0.0002 | |
| SRP193095 | ARL6IP5 | 10550 | RNAseq | -0.8888 | 0.0000 | |
| SRP219564 | ARL6IP5 | 10550 | RNAseq | -0.6039 | 0.2141 | |
| TCGA | ARL6IP5 | 10550 | RNAseq | -0.2648 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by ARL6IP5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARL6IP5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARL6IP5 | 10550 | 1 | 19 | 10 | |
| GSE20123 | ARL6IP5 | 10550 | 1 | 19 | 10 | |
| GSE43470 | ARL6IP5 | 10550 | 0 | 20 | 23 | |
| GSE46452 | ARL6IP5 | 10550 | 2 | 17 | 40 | |
| GSE47630 | ARL6IP5 | 10550 | 1 | 23 | 16 | |
| GSE54993 | ARL6IP5 | 10550 | 5 | 3 | 62 | |
| GSE54994 | ARL6IP5 | 10550 | 1 | 33 | 19 | |
| GSE60625 | ARL6IP5 | 10550 | 3 | 1 | 7 | |
| GSE74703 | ARL6IP5 | 10550 | 0 | 16 | 20 | |
| GSE74704 | ARL6IP5 | 10550 | 1 | 13 | 6 | |
| TCGA | ARL6IP5 | 10550 | 0 | 79 | 17 |
Total number of gains: 15; Total number of losses: 243; Total Number of normals: 230.
Somatic mutations of ARL6IP5:
Generating mutation plots.
Highly correlated genes for ARL6IP5:
Showing top 20/1854 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARL6IP5 | RAP1A | 0.762621 | 11 | 0 | 11 |
| ARL6IP5 | KAT2B | 0.762164 | 12 | 0 | 12 |
| ARL6IP5 | FBXO10 | 0.759343 | 4 | 0 | 4 |
| ARL6IP5 | PPP2R5E | 0.756403 | 3 | 0 | 3 |
| ARL6IP5 | SUCLG2 | 0.751314 | 13 | 0 | 12 |
| ARL6IP5 | KDM5D | 0.749975 | 3 | 0 | 3 |
| ARL6IP5 | ZCCHC9 | 0.735172 | 4 | 0 | 4 |
| ARL6IP5 | AK3 | 0.733631 | 7 | 0 | 6 |
| ARL6IP5 | EVC2 | 0.732167 | 3 | 0 | 3 |
| ARL6IP5 | LMBRD1 | 0.729544 | 12 | 0 | 12 |
| ARL6IP5 | FOXP1 | 0.72785 | 6 | 0 | 6 |
| ARL6IP5 | LRRK2 | 0.726459 | 8 | 0 | 8 |
| ARL6IP5 | EIF4E3 | 0.72619 | 8 | 0 | 6 |
| ARL6IP5 | SUSD1 | 0.725512 | 3 | 0 | 3 |
| ARL6IP5 | RNF185 | 0.723359 | 4 | 0 | 4 |
| ARL6IP5 | FBXW5 | 0.721512 | 5 | 0 | 5 |
| ARL6IP5 | HDHD2 | 0.721355 | 5 | 0 | 5 |
| ARL6IP5 | CCDC25 | 0.721343 | 3 | 0 | 3 |
| ARL6IP5 | FBXL5 | 0.720312 | 12 | 0 | 11 |
| ARL6IP5 | FYCO1 | 0.719791 | 13 | 0 | 11 |
For details and further investigation, click here
