| Full name: ring finger protein 185 | Alias Symbol: FLJ38628 | ||
| Type: protein-coding gene | Cytoband: 22q12.2 | ||
| Entrez ID: 91445 | HGNC ID: HGNC:26783 | Ensembl Gene: ENSG00000138942 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RNF185:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNF185 | 91445 | 224750_at | -0.4305 | 0.0647 | |
| GSE26886 | RNF185 | 91445 | 224750_at | -0.3403 | 0.0287 | |
| GSE45670 | RNF185 | 91445 | 224750_at | -0.0143 | 0.9324 | |
| GSE53622 | RNF185 | 91445 | 132258 | -0.4550 | 0.0000 | |
| GSE53624 | RNF185 | 91445 | 26087 | -0.3104 | 0.0000 | |
| GSE63941 | RNF185 | 91445 | 224750_at | 0.5065 | 0.2115 | |
| GSE77861 | RNF185 | 91445 | 224750_at | -0.0440 | 0.8238 | |
| GSE97050 | RNF185 | 91445 | A_32_P15421 | -0.5841 | 0.1210 | |
| SRP007169 | RNF185 | 91445 | RNAseq | -0.8882 | 0.0048 | |
| SRP008496 | RNF185 | 91445 | RNAseq | -0.7642 | 0.0000 | |
| SRP064894 | RNF185 | 91445 | RNAseq | -0.2847 | 0.0190 | |
| SRP133303 | RNF185 | 91445 | RNAseq | -0.2630 | 0.1346 | |
| SRP159526 | RNF185 | 91445 | RNAseq | -0.4881 | 0.0006 | |
| SRP193095 | RNF185 | 91445 | RNAseq | -0.4534 | 0.0000 | |
| SRP219564 | RNF185 | 91445 | RNAseq | -0.3980 | 0.1912 | |
| TCGA | RNF185 | 91445 | RNAseq | -0.1519 | 0.0011 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RNF185 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNF185:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF185 | 91445 | 4 | 5 | 21 | |
| GSE20123 | RNF185 | 91445 | 4 | 4 | 22 | |
| GSE43470 | RNF185 | 91445 | 4 | 5 | 34 | |
| GSE46452 | RNF185 | 91445 | 31 | 1 | 27 | |
| GSE47630 | RNF185 | 91445 | 8 | 5 | 27 | |
| GSE54993 | RNF185 | 91445 | 3 | 6 | 61 | |
| GSE54994 | RNF185 | 91445 | 12 | 7 | 34 | |
| GSE60625 | RNF185 | 91445 | 5 | 0 | 6 | |
| GSE74703 | RNF185 | 91445 | 4 | 5 | 27 | |
| GSE74704 | RNF185 | 91445 | 1 | 1 | 18 | |
| TCGA | RNF185 | 91445 | 27 | 15 | 54 |
Total number of gains: 103; Total number of losses: 54; Total Number of normals: 331.
Somatic mutations of RNF185:
Generating mutation plots.
Highly correlated genes for RNF185:
Showing top 20/671 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF185 | SPAG8 | 0.808584 | 3 | 0 | 3 |
| RNF185 | MLYCD | 0.792993 | 3 | 0 | 3 |
| RNF185 | PPP1R3B | 0.785299 | 3 | 0 | 3 |
| RNF185 | SNRK | 0.780608 | 3 | 0 | 3 |
| RNF185 | HEMK1 | 0.77511 | 3 | 0 | 3 |
| RNF185 | BRK1 | 0.771514 | 4 | 0 | 4 |
| RNF185 | INSRR | 0.765924 | 3 | 0 | 3 |
| RNF185 | DTWD1 | 0.758254 | 3 | 0 | 3 |
| RNF185 | NDUFS4 | 0.756136 | 3 | 0 | 3 |
| RNF185 | ROR1 | 0.755596 | 3 | 0 | 3 |
| RNF185 | PRICKLE2 | 0.748786 | 3 | 0 | 3 |
| RNF185 | GNE | 0.74758 | 3 | 0 | 3 |
| RNF185 | SRP14 | 0.746499 | 3 | 0 | 3 |
| RNF185 | CALCOCO2 | 0.746291 | 4 | 0 | 4 |
| RNF185 | GRHPR | 0.743905 | 3 | 0 | 3 |
| RNF185 | GCC2 | 0.743205 | 3 | 0 | 3 |
| RNF185 | HBP1 | 0.7418 | 3 | 0 | 3 |
| RNF185 | ANKRA2 | 0.736276 | 3 | 0 | 3 |
| RNF185 | GAB1 | 0.734505 | 4 | 0 | 3 |
| RNF185 | PIK3C2A | 0.734401 | 4 | 0 | 3 |
For details and further investigation, click here
