| Full name: FYVE and coiled-coil domain containing 1 | Alias Symbol: FLJ13335|ZFYVE7 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 79443 | HGNC ID: HGNC:14673 | Ensembl Gene: ENSG00000163820 | OMIM ID: 607182 |
| Drug and gene relationship at DGIdb | |||
Expression of FYCO1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FYCO1 | 79443 | 218204_s_at | -1.1006 | 0.0354 | |
| GSE20347 | FYCO1 | 79443 | 218204_s_at | -1.4614 | 0.0000 | |
| GSE23400 | FYCO1 | 79443 | 218204_s_at | -0.8227 | 0.0000 | |
| GSE26886 | FYCO1 | 79443 | 218204_s_at | -1.3950 | 0.0002 | |
| GSE29001 | FYCO1 | 79443 | 218204_s_at | -0.9721 | 0.0012 | |
| GSE38129 | FYCO1 | 79443 | 218204_s_at | -1.5180 | 0.0000 | |
| GSE45670 | FYCO1 | 79443 | 218204_s_at | -0.9534 | 0.0000 | |
| GSE53622 | FYCO1 | 79443 | 74743 | -1.2756 | 0.0000 | |
| GSE53624 | FYCO1 | 79443 | 74743 | -1.4090 | 0.0000 | |
| GSE63941 | FYCO1 | 79443 | 218204_s_at | -2.9419 | 0.0000 | |
| GSE77861 | FYCO1 | 79443 | 1555523_a_at | -0.2139 | 0.0218 | |
| GSE97050 | FYCO1 | 79443 | A_23_P212339 | -1.1159 | 0.0726 | |
| SRP007169 | FYCO1 | 79443 | RNAseq | -0.2627 | 0.5947 | |
| SRP008496 | FYCO1 | 79443 | RNAseq | -0.0940 | 0.7832 | |
| SRP064894 | FYCO1 | 79443 | RNAseq | -1.0600 | 0.0000 | |
| SRP133303 | FYCO1 | 79443 | RNAseq | -0.9914 | 0.0054 | |
| SRP159526 | FYCO1 | 79443 | RNAseq | -1.2313 | 0.0013 | |
| SRP193095 | FYCO1 | 79443 | RNAseq | -0.7366 | 0.0000 | |
| SRP219564 | FYCO1 | 79443 | RNAseq | -0.9876 | 0.0926 | |
| TCGA | FYCO1 | 79443 | RNAseq | -0.4789 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 9.
Survival by FYCO1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FYCO1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FYCO1 | 79443 | 0 | 17 | 13 | |
| GSE20123 | FYCO1 | 79443 | 0 | 18 | 12 | |
| GSE43470 | FYCO1 | 79443 | 0 | 20 | 23 | |
| GSE46452 | FYCO1 | 79443 | 2 | 17 | 40 | |
| GSE47630 | FYCO1 | 79443 | 2 | 23 | 15 | |
| GSE54993 | FYCO1 | 79443 | 7 | 2 | 61 | |
| GSE54994 | FYCO1 | 79443 | 0 | 36 | 17 | |
| GSE60625 | FYCO1 | 79443 | 5 | 0 | 6 | |
| GSE74703 | FYCO1 | 79443 | 0 | 15 | 21 | |
| GSE74704 | FYCO1 | 79443 | 0 | 12 | 8 | |
| TCGA | FYCO1 | 79443 | 1 | 75 | 20 |
Total number of gains: 17; Total number of losses: 235; Total Number of normals: 236.
Somatic mutations of FYCO1:
Generating mutation plots.
Highly correlated genes for FYCO1:
Showing top 20/1859 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FYCO1 | ANGPTL1 | 0.804483 | 6 | 0 | 6 |
| FYCO1 | TBX5-AS1 | 0.786178 | 3 | 0 | 3 |
| FYCO1 | RASSF3 | 0.783858 | 5 | 0 | 5 |
| FYCO1 | ASPA | 0.783499 | 10 | 0 | 10 |
| FYCO1 | SLMAP | 0.782215 | 9 | 0 | 9 |
| FYCO1 | RGMB | 0.780278 | 4 | 0 | 4 |
| FYCO1 | NEGR1 | 0.779917 | 6 | 0 | 6 |
| FYCO1 | RSPO2 | 0.774152 | 3 | 0 | 3 |
| FYCO1 | CYP4V2 | 0.773456 | 4 | 0 | 4 |
| FYCO1 | RAP1A | 0.773193 | 11 | 0 | 11 |
| FYCO1 | DACT3 | 0.772913 | 4 | 0 | 4 |
| FYCO1 | SORCS1 | 0.769499 | 4 | 0 | 4 |
| FYCO1 | ASB5 | 0.759838 | 6 | 0 | 6 |
| FYCO1 | LRRK2 | 0.757918 | 8 | 0 | 7 |
| FYCO1 | MYOCD | 0.755882 | 6 | 0 | 5 |
| FYCO1 | SNRK | 0.754425 | 11 | 0 | 11 |
| FYCO1 | EIF4E3 | 0.753663 | 8 | 0 | 7 |
| FYCO1 | HOXA4 | 0.753266 | 7 | 0 | 7 |
| FYCO1 | CNOT4 | 0.751143 | 3 | 0 | 3 |
| FYCO1 | PLCXD3 | 0.750451 | 4 | 0 | 4 |
For details and further investigation, click here
