| Full name: ubiquitin conjugating enzyme E2 E3 | Alias Symbol: UbcH9 | ||
| Type: protein-coding gene | Cytoband: 2q31.3 | ||
| Entrez ID: 10477 | HGNC ID: HGNC:12479 | Ensembl Gene: ENSG00000170035 | OMIM ID: 604151 |
| Drug and gene relationship at DGIdb | |||
Expression of UBE2E3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBE2E3 | 10477 | 210024_s_at | 0.6899 | 0.0426 | |
| GSE20347 | UBE2E3 | 10477 | 210024_s_at | 0.4976 | 0.0172 | |
| GSE23400 | UBE2E3 | 10477 | 210024_s_at | 0.7116 | 0.0000 | |
| GSE26886 | UBE2E3 | 10477 | 210024_s_at | 1.0046 | 0.0001 | |
| GSE29001 | UBE2E3 | 10477 | 210024_s_at | 0.5702 | 0.1542 | |
| GSE38129 | UBE2E3 | 10477 | 210024_s_at | 0.6920 | 0.0000 | |
| GSE45670 | UBE2E3 | 10477 | 210024_s_at | 0.3532 | 0.0308 | |
| GSE53622 | UBE2E3 | 10477 | 104100 | 0.7072 | 0.0000 | |
| GSE53624 | UBE2E3 | 10477 | 97112 | 0.7276 | 0.0000 | |
| GSE63941 | UBE2E3 | 10477 | 210024_s_at | -0.5566 | 0.2562 | |
| GSE77861 | UBE2E3 | 10477 | 210024_s_at | 0.2101 | 0.4438 | |
| GSE97050 | UBE2E3 | 10477 | A_24_P148450 | 0.5974 | 0.1453 | |
| SRP007169 | UBE2E3 | 10477 | RNAseq | 0.2025 | 0.5398 | |
| SRP008496 | UBE2E3 | 10477 | RNAseq | 0.4432 | 0.0294 | |
| SRP064894 | UBE2E3 | 10477 | RNAseq | 0.5396 | 0.0002 | |
| SRP133303 | UBE2E3 | 10477 | RNAseq | 0.6268 | 0.0040 | |
| SRP159526 | UBE2E3 | 10477 | RNAseq | 0.4325 | 0.0411 | |
| SRP193095 | UBE2E3 | 10477 | RNAseq | 0.3972 | 0.0058 | |
| SRP219564 | UBE2E3 | 10477 | RNAseq | 0.3205 | 0.2459 | |
| TCGA | UBE2E3 | 10477 | RNAseq | 0.1008 | 0.0351 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by UBE2E3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBE2E3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBE2E3 | 10477 | 5 | 1 | 24 | |
| GSE20123 | UBE2E3 | 10477 | 5 | 1 | 24 | |
| GSE43470 | UBE2E3 | 10477 | 5 | 1 | 37 | |
| GSE46452 | UBE2E3 | 10477 | 1 | 4 | 54 | |
| GSE47630 | UBE2E3 | 10477 | 4 | 4 | 32 | |
| GSE54993 | UBE2E3 | 10477 | 0 | 5 | 65 | |
| GSE54994 | UBE2E3 | 10477 | 11 | 5 | 37 | |
| GSE60625 | UBE2E3 | 10477 | 0 | 3 | 8 | |
| GSE74703 | UBE2E3 | 10477 | 4 | 1 | 31 | |
| GSE74704 | UBE2E3 | 10477 | 2 | 1 | 17 | |
| TCGA | UBE2E3 | 10477 | 25 | 8 | 63 |
Total number of gains: 62; Total number of losses: 34; Total Number of normals: 392.
Somatic mutations of UBE2E3:
Generating mutation plots.
Highly correlated genes for UBE2E3:
Showing top 20/1581 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBE2E3 | PYCR2 | 0.744344 | 3 | 0 | 3 |
| UBE2E3 | MTHFD1L | 0.741286 | 3 | 0 | 3 |
| UBE2E3 | SNAP47 | 0.7373 | 3 | 0 | 3 |
| UBE2E3 | SIX4 | 0.732923 | 5 | 0 | 5 |
| UBE2E3 | ARL6IP6 | 0.731152 | 7 | 0 | 7 |
| UBE2E3 | B3GALT6 | 0.7243 | 5 | 0 | 5 |
| UBE2E3 | RBM4 | 0.722127 | 3 | 0 | 3 |
| UBE2E3 | HAT1 | 0.721797 | 12 | 0 | 11 |
| UBE2E3 | XXYLT1 | 0.721576 | 4 | 0 | 4 |
| UBE2E3 | LRRCC1 | 0.71825 | 3 | 0 | 3 |
| UBE2E3 | IPO4 | 0.706971 | 5 | 0 | 4 |
| UBE2E3 | PRKDC | 0.706895 | 10 | 0 | 10 |
| UBE2E3 | NLN | 0.703386 | 4 | 0 | 3 |
| UBE2E3 | DNAJB11 | 0.701743 | 5 | 0 | 4 |
| UBE2E3 | LIN9 | 0.698478 | 6 | 0 | 5 |
| UBE2E3 | ILF2 | 0.695456 | 10 | 0 | 9 |
| UBE2E3 | REST | 0.694978 | 3 | 0 | 3 |
| UBE2E3 | PDE7A | 0.694622 | 6 | 0 | 5 |
| UBE2E3 | ANAPC1 | 0.694124 | 3 | 0 | 3 |
| UBE2E3 | SAAL1 | 0.691678 | 5 | 0 | 4 |
For details and further investigation, click here
