| Full name: chromosome 1 open reading frame 112 | Alias Symbol: FLJ10706 | ||
| Type: protein-coding gene | Cytoband: 1q24.2 | ||
| Entrez ID: 55732 | HGNC ID: HGNC:25565 | Ensembl Gene: ENSG00000000460 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of C1orf112:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C1orf112 | 55732 | 220840_s_at | 1.3674 | 0.0213 | |
| GSE20347 | C1orf112 | 55732 | 220840_s_at | 1.0689 | 0.0000 | |
| GSE23400 | C1orf112 | 55732 | 220840_s_at | 0.5947 | 0.0000 | |
| GSE26886 | C1orf112 | 55732 | 220840_s_at | 0.5645 | 0.0002 | |
| GSE29001 | C1orf112 | 55732 | 220840_s_at | 0.7303 | 0.0013 | |
| GSE38129 | C1orf112 | 55732 | 220840_s_at | 1.3360 | 0.0000 | |
| GSE45670 | C1orf112 | 55732 | 220840_s_at | 1.0061 | 0.0000 | |
| GSE63941 | C1orf112 | 55732 | 220840_s_at | 2.0920 | 0.0003 | |
| GSE77861 | C1orf112 | 55732 | 220840_s_at | 0.5179 | 0.0209 | |
| GSE97050 | C1orf112 | 55732 | A_23_P11862 | 0.2559 | 0.3159 | |
| SRP007169 | C1orf112 | 55732 | RNAseq | 1.8834 | 0.0009 | |
| SRP008496 | C1orf112 | 55732 | RNAseq | 1.2717 | 0.0291 | |
| SRP064894 | C1orf112 | 55732 | RNAseq | 1.0729 | 0.0000 | |
| SRP133303 | C1orf112 | 55732 | RNAseq | 1.2166 | 0.0000 | |
| SRP159526 | C1orf112 | 55732 | RNAseq | 1.6007 | 0.0000 | |
| SRP193095 | C1orf112 | 55732 | RNAseq | 0.7702 | 0.0000 | |
| SRP219564 | C1orf112 | 55732 | RNAseq | 1.1855 | 0.0023 | |
| TCGA | C1orf112 | 55732 | RNAseq | 0.6897 | 0.0000 |
Upregulated datasets: 11; Downregulated datasets: 0.
Survival by C1orf112 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of C1orf112:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C1orf112 | 55732 | 12 | 1 | 17 | |
| GSE20123 | C1orf112 | 55732 | 12 | 1 | 17 | |
| GSE43470 | C1orf112 | 55732 | 7 | 2 | 34 | |
| GSE46452 | C1orf112 | 55732 | 3 | 1 | 55 | |
| GSE47630 | C1orf112 | 55732 | 14 | 0 | 26 | |
| GSE54993 | C1orf112 | 55732 | 0 | 6 | 64 | |
| GSE54994 | C1orf112 | 55732 | 16 | 0 | 37 | |
| GSE60625 | C1orf112 | 55732 | 0 | 0 | 11 | |
| GSE74703 | C1orf112 | 55732 | 7 | 2 | 27 | |
| GSE74704 | C1orf112 | 55732 | 6 | 0 | 14 | |
| TCGA | C1orf112 | 55732 | 43 | 3 | 50 |
Total number of gains: 120; Total number of losses: 16; Total Number of normals: 352.
Somatic mutations of C1orf112:
Generating mutation plots.
Highly correlated genes for C1orf112:
Showing top 20/2030 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C1orf112 | C12orf57 | 0.806432 | 3 | 0 | 3 |
| C1orf112 | MRPL14 | 0.803946 | 5 | 0 | 5 |
| C1orf112 | EXO1 | 0.799443 | 10 | 0 | 10 |
| C1orf112 | SKA3 | 0.798033 | 5 | 0 | 5 |
| C1orf112 | HJURP | 0.795437 | 10 | 0 | 9 |
| C1orf112 | MMS19 | 0.790336 | 3 | 0 | 3 |
| C1orf112 | E2F7 | 0.786466 | 3 | 0 | 3 |
| C1orf112 | CKS1B | 0.785111 | 11 | 0 | 10 |
| C1orf112 | GMNN | 0.784856 | 11 | 0 | 10 |
| C1orf112 | CENPF | 0.782268 | 11 | 0 | 11 |
| C1orf112 | POLE2 | 0.78091 | 8 | 0 | 8 |
| C1orf112 | UBE2T | 0.780254 | 7 | 0 | 6 |
| C1orf112 | DTL | 0.777092 | 11 | 0 | 11 |
| C1orf112 | ERCC6L | 0.776448 | 9 | 0 | 8 |
| C1orf112 | NEK2 | 0.776337 | 11 | 0 | 10 |
| C1orf112 | CEP55 | 0.774203 | 10 | 0 | 9 |
| C1orf112 | MCM3 | 0.773538 | 10 | 0 | 10 |
| C1orf112 | NUF2 | 0.771377 | 7 | 0 | 7 |
| C1orf112 | BUB1 | 0.770707 | 9 | 0 | 7 |
| C1orf112 | DBF4 | 0.770471 | 10 | 0 | 10 |
For details and further investigation, click here
