| Full name: matrix metallopeptidase 26 | Alias Symbol: endometase|MGC126590|MGC126592 | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 56547 | HGNC ID: HGNC:14249 | Ensembl Gene: ENSG00000167346 | OMIM ID: 605470 |
| Drug and gene relationship at DGIdb | |||
Expression of MMP26:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MMP26 | 56547 | 220541_at | -0.0783 | 0.6733 | |
| GSE20347 | MMP26 | 56547 | 220541_at | 0.0515 | 0.6366 | |
| GSE23400 | MMP26 | 56547 | 220541_at | -0.0625 | 0.0817 | |
| GSE26886 | MMP26 | 56547 | 220541_at | 0.1189 | 0.3995 | |
| GSE29001 | MMP26 | 56547 | 220541_at | -0.0745 | 0.7543 | |
| GSE38129 | MMP26 | 56547 | 220541_at | -0.0693 | 0.5652 | |
| GSE45670 | MMP26 | 56547 | 220541_at | 0.0660 | 0.4724 | |
| GSE53622 | MMP26 | 56547 | 5327 | -0.2533 | 0.0281 | |
| GSE53624 | MMP26 | 56547 | 5327 | 0.0422 | 0.5445 | |
| GSE63941 | MMP26 | 56547 | 220541_at | 0.2154 | 0.1903 | |
| GSE77861 | MMP26 | 56547 | 220541_at | -0.1232 | 0.3909 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MMP26 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MMP26:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MMP26 | 56547 | 1 | 11 | 18 | |
| GSE20123 | MMP26 | 56547 | 1 | 11 | 18 | |
| GSE43470 | MMP26 | 56547 | 1 | 8 | 34 | |
| GSE46452 | MMP26 | 56547 | 7 | 8 | 44 | |
| GSE47630 | MMP26 | 56547 | 3 | 13 | 24 | |
| GSE54993 | MMP26 | 56547 | 3 | 1 | 66 | |
| GSE54994 | MMP26 | 56547 | 1 | 13 | 39 | |
| GSE60625 | MMP26 | 56547 | 0 | 0 | 11 | |
| GSE74703 | MMP26 | 56547 | 1 | 6 | 29 | |
| GSE74704 | MMP26 | 56547 | 0 | 8 | 12 | |
| TCGA | MMP26 | 56547 | 8 | 39 | 49 |
Total number of gains: 26; Total number of losses: 118; Total Number of normals: 344.
Somatic mutations of MMP26:
Generating mutation plots.
Highly correlated genes for MMP26:
Showing top 20/591 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MMP26 | CIITA | 0.736366 | 5 | 0 | 5 |
| MMP26 | GAD2 | 0.707727 | 5 | 0 | 5 |
| MMP26 | CHRNA6 | 0.703163 | 3 | 0 | 3 |
| MMP26 | NTNG1 | 0.70072 | 4 | 0 | 4 |
| MMP26 | NEUROD2 | 0.694835 | 4 | 0 | 4 |
| MMP26 | PRODH2 | 0.688605 | 5 | 0 | 5 |
| MMP26 | ARPP21 | 0.68421 | 5 | 0 | 5 |
| MMP26 | CCDC87 | 0.680676 | 4 | 0 | 4 |
| MMP26 | GK2 | 0.676538 | 4 | 0 | 4 |
| MMP26 | KRT38 | 0.674343 | 4 | 0 | 3 |
| MMP26 | FOXN3-AS2 | 0.673544 | 6 | 0 | 5 |
| MMP26 | NOL4 | 0.670111 | 4 | 0 | 3 |
| MMP26 | NXPE4 | 0.669031 | 5 | 0 | 4 |
| MMP26 | FGF5 | 0.668768 | 3 | 0 | 3 |
| MMP26 | NNAT | 0.667938 | 5 | 0 | 5 |
| MMP26 | CYSLTR2 | 0.66644 | 4 | 0 | 4 |
| MMP26 | PRKAR1B | 0.664961 | 3 | 0 | 3 |
| MMP26 | CER1 | 0.664694 | 6 | 0 | 5 |
| MMP26 | C20orf173 | 0.664124 | 3 | 0 | 3 |
| MMP26 | STXBP5L | 0.664049 | 4 | 0 | 4 |
For details and further investigation, click here
