| Full name: N-acylsphingosine amidohydrolase 2B | Alias Symbol: bA449O16.3|ASAH2L|bA98I6.3 | ||
| Type: protein-coding gene | Cytoband: 10q11.23 | ||
| Entrez ID: 653308 | HGNC ID: HGNC:23456 | Ensembl Gene: ENSG00000204147 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ASAH2B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ASAH2B | 653308 | 229793_at | 0.0464 | 0.9198 | |
| GSE26886 | ASAH2B | 653308 | 229793_at | 0.3926 | 0.2157 | |
| GSE45670 | ASAH2B | 653308 | 229793_at | 0.4216 | 0.0154 | |
| GSE63941 | ASAH2B | 653308 | 229793_at | -0.7406 | 0.1546 | |
| GSE77861 | ASAH2B | 653308 | 229793_at | -0.0551 | 0.8513 | |
| SRP007169 | ASAH2B | 653308 | RNAseq | 0.0890 | 0.8592 | |
| SRP008496 | ASAH2B | 653308 | RNAseq | 0.0219 | 0.9545 | |
| SRP064894 | ASAH2B | 653308 | RNAseq | -0.0708 | 0.7065 | |
| SRP133303 | ASAH2B | 653308 | RNAseq | 0.1898 | 0.2395 | |
| SRP159526 | ASAH2B | 653308 | RNAseq | -0.3101 | 0.3809 | |
| SRP193095 | ASAH2B | 653308 | RNAseq | -0.3315 | 0.0245 | |
| SRP219564 | ASAH2B | 653308 | RNAseq | 0.1119 | 0.7663 | |
| TCGA | ASAH2B | 653308 | RNAseq | 0.4881 | 0.4859 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ASAH2B expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ASAH2B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ASAH2B | 653308 | 3 | 5 | 22 | |
| GSE20123 | ASAH2B | 653308 | 3 | 5 | 22 | |
| GSE43470 | ASAH2B | 653308 | 2 | 4 | 37 | |
| GSE46452 | ASAH2B | 653308 | 0 | 13 | 46 | |
| GSE47630 | ASAH2B | 653308 | 4 | 12 | 24 | |
| GSE54993 | ASAH2B | 653308 | 9 | 0 | 61 | |
| GSE54994 | ASAH2B | 653308 | 2 | 10 | 41 | |
| GSE60625 | ASAH2B | 653308 | 0 | 0 | 11 | |
| GSE74703 | ASAH2B | 653308 | 2 | 2 | 32 | |
| GSE74704 | ASAH2B | 653308 | 1 | 4 | 15 | |
| TCGA | ASAH2B | 653308 | 12 | 22 | 62 |
Total number of gains: 38; Total number of losses: 77; Total Number of normals: 373.
Somatic mutations of ASAH2B:
Generating mutation plots.
Highly correlated genes for ASAH2B:
Showing top 20/23 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ASAH2B | FRS2 | 0.669941 | 3 | 0 | 3 |
| ASAH2B | ZNF559 | 0.668886 | 3 | 0 | 3 |
| ASAH2B | PARG | 0.66395 | 4 | 0 | 3 |
| ASAH2B | KIF20B | 0.641836 | 3 | 0 | 3 |
| ASAH2B | GPAM | 0.639489 | 4 | 0 | 3 |
| ASAH2B | NOC3L | 0.638802 | 3 | 0 | 3 |
| ASAH2B | TBCEL | 0.637771 | 3 | 0 | 3 |
| ASAH2B | CYB5D1 | 0.635104 | 3 | 0 | 3 |
| ASAH2B | LRRC34 | 0.614416 | 4 | 0 | 3 |
| ASAH2B | CHUK | 0.608153 | 4 | 0 | 4 |
| ASAH2B | TMEM181 | 0.581465 | 3 | 0 | 3 |
| ASAH2B | SKP2 | 0.581408 | 3 | 0 | 3 |
| ASAH2B | ZDHHC16 | 0.581205 | 4 | 0 | 3 |
| ASAH2B | ZFP37 | 0.563562 | 4 | 0 | 3 |
| ASAH2B | RECQL | 0.557554 | 3 | 0 | 3 |
| ASAH2B | SENP6 | 0.556927 | 4 | 0 | 3 |
| ASAH2B | STAG1 | 0.541728 | 3 | 0 | 3 |
| ASAH2B | GMFB | 0.541477 | 3 | 0 | 3 |
| ASAH2B | CENPL | 0.539472 | 3 | 0 | 3 |
| ASAH2B | ZFR | 0.538496 | 4 | 0 | 3 |
For details and further investigation, click here
