| Full name: RecQ like helicase | Alias Symbol: RecQ1|RecQL1 | ||
| Type: protein-coding gene | Cytoband: 12p12.1 | ||
| Entrez ID: 5965 | HGNC ID: HGNC:9948 | Ensembl Gene: ENSG00000004700 | OMIM ID: 600537 |
| Drug and gene relationship at DGIdb | |||
Expression of RECQL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RECQL | 5965 | 212918_at | 0.1818 | 0.6439 | |
| GSE20347 | RECQL | 5965 | 212917_x_at | 0.5904 | 0.0014 | |
| GSE23400 | RECQL | 5965 | 212918_at | 0.5072 | 0.0001 | |
| GSE26886 | RECQL | 5965 | 212918_at | 0.0830 | 0.8387 | |
| GSE29001 | RECQL | 5965 | 212918_at | 0.3942 | 0.3642 | |
| GSE38129 | RECQL | 5965 | 212917_x_at | 0.4730 | 0.0332 | |
| GSE45670 | RECQL | 5965 | 212917_x_at | 0.4269 | 0.0874 | |
| GSE53622 | RECQL | 5965 | 61318 | 0.1630 | 0.0413 | |
| GSE53624 | RECQL | 5965 | 61318 | 0.0083 | 0.9160 | |
| GSE63941 | RECQL | 5965 | 212918_at | -0.7816 | 0.1555 | |
| GSE77861 | RECQL | 5965 | 212918_at | 0.3574 | 0.5475 | |
| GSE97050 | RECQL | 5965 | A_23_P25215 | 0.1979 | 0.4658 | |
| SRP007169 | RECQL | 5965 | RNAseq | -2.3307 | 0.0009 | |
| SRP008496 | RECQL | 5965 | RNAseq | -1.4311 | 0.0325 | |
| SRP064894 | RECQL | 5965 | RNAseq | 0.5493 | 0.0598 | |
| SRP133303 | RECQL | 5965 | RNAseq | 0.5933 | 0.0055 | |
| SRP159526 | RECQL | 5965 | RNAseq | 0.2094 | 0.4922 | |
| SRP193095 | RECQL | 5965 | RNAseq | 0.1713 | 0.3224 | |
| SRP219564 | RECQL | 5965 | RNAseq | 0.2754 | 0.4951 | |
| TCGA | RECQL | 5965 | RNAseq | 0.2713 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by RECQL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RECQL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RECQL | 5965 | 9 | 2 | 19 | |
| GSE20123 | RECQL | 5965 | 9 | 2 | 19 | |
| GSE43470 | RECQL | 5965 | 9 | 4 | 30 | |
| GSE46452 | RECQL | 5965 | 10 | 1 | 48 | |
| GSE47630 | RECQL | 5965 | 14 | 1 | 25 | |
| GSE54993 | RECQL | 5965 | 1 | 9 | 60 | |
| GSE54994 | RECQL | 5965 | 11 | 2 | 40 | |
| GSE60625 | RECQL | 5965 | 0 | 1 | 10 | |
| GSE74703 | RECQL | 5965 | 9 | 3 | 24 | |
| GSE74704 | RECQL | 5965 | 6 | 1 | 13 | |
| TCGA | RECQL | 5965 | 42 | 5 | 49 |
Total number of gains: 120; Total number of losses: 31; Total Number of normals: 337.
Somatic mutations of RECQL:
Generating mutation plots.
Highly correlated genes for RECQL:
Showing top 20/445 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RECQL | DDX20 | 0.749132 | 3 | 0 | 3 |
| RECQL | MAD2L2 | 0.744883 | 3 | 0 | 3 |
| RECQL | NOL9 | 0.74207 | 3 | 0 | 3 |
| RECQL | CTBP2 | 0.739591 | 3 | 0 | 3 |
| RECQL | KRI1 | 0.735162 | 3 | 0 | 3 |
| RECQL | IFT52 | 0.734528 | 4 | 0 | 4 |
| RECQL | DNAJC19 | 0.728497 | 3 | 0 | 3 |
| RECQL | XPO4 | 0.724194 | 3 | 0 | 3 |
| RECQL | TMEM216 | 0.71234 | 3 | 0 | 3 |
| RECQL | PSMA5 | 0.701944 | 5 | 0 | 4 |
| RECQL | MAP4K3 | 0.700317 | 3 | 0 | 3 |
| RECQL | MYO9B | 0.69897 | 4 | 0 | 3 |
| RECQL | WDFY1 | 0.697744 | 3 | 0 | 3 |
| RECQL | MKLN1 | 0.69302 | 3 | 0 | 3 |
| RECQL | SLC43A2 | 0.690838 | 3 | 0 | 3 |
| RECQL | TMTC3 | 0.690302 | 4 | 0 | 3 |
| RECQL | SLC30A6 | 0.689789 | 4 | 0 | 3 |
| RECQL | ZNHIT6 | 0.689771 | 3 | 0 | 3 |
| RECQL | MAD2L1BP | 0.68847 | 4 | 0 | 4 |
| RECQL | MRPS11 | 0.680939 | 4 | 0 | 3 |
For details and further investigation, click here
