| Full name: hemoglobin subunit epsilon 1 | Alias Symbol: HBE | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 3046 | HGNC ID: HGNC:4830 | Ensembl Gene: ENSG00000213931 | OMIM ID: 142100 |
| Drug and gene relationship at DGIdb | |||
Expression of HBE1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HBE1 | 3046 | 205919_at | 0.0210 | 0.9468 | |
| GSE20347 | HBE1 | 3046 | 205919_at | 0.0930 | 0.3515 | |
| GSE23400 | HBE1 | 3046 | 205919_at | -0.0090 | 0.8493 | |
| GSE26886 | HBE1 | 3046 | 205919_at | 0.1973 | 0.0956 | |
| GSE29001 | HBE1 | 3046 | 205919_at | 0.0577 | 0.7591 | |
| GSE38129 | HBE1 | 3046 | 205919_at | -0.0518 | 0.5674 | |
| GSE45670 | HBE1 | 3046 | 205919_at | 0.2674 | 0.3827 | |
| GSE53622 | HBE1 | 3046 | 48631 | 0.2615 | 0.0729 | |
| GSE53624 | HBE1 | 3046 | 48631 | 0.4491 | 0.0000 | |
| GSE63941 | HBE1 | 3046 | 205919_at | 0.7714 | 0.6031 | |
| GSE77861 | HBE1 | 3046 | 205919_at | -0.1023 | 0.4838 | |
| GSE97050 | HBE1 | 3046 | A_23_P47665 | 0.2312 | 0.3418 | |
| TCGA | HBE1 | 3046 | RNAseq | 3.8927 | 0.0106 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by HBE1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HBE1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HBE1 | 3046 | 1 | 11 | 18 | |
| GSE20123 | HBE1 | 3046 | 1 | 11 | 18 | |
| GSE43470 | HBE1 | 3046 | 1 | 8 | 34 | |
| GSE46452 | HBE1 | 3046 | 7 | 8 | 44 | |
| GSE47630 | HBE1 | 3046 | 3 | 13 | 24 | |
| GSE54993 | HBE1 | 3046 | 3 | 1 | 66 | |
| GSE54994 | HBE1 | 3046 | 2 | 12 | 39 | |
| GSE60625 | HBE1 | 3046 | 0 | 0 | 11 | |
| GSE74703 | HBE1 | 3046 | 1 | 6 | 29 | |
| GSE74704 | HBE1 | 3046 | 0 | 8 | 12 | |
| TCGA | HBE1 | 3046 | 8 | 39 | 49 |
Total number of gains: 27; Total number of losses: 117; Total Number of normals: 344.
Somatic mutations of HBE1:
Generating mutation plots.
Highly correlated genes for HBE1:
Showing top 20/346 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HBE1 | ASPDH | 0.684211 | 3 | 0 | 3 |
| HBE1 | FOLH1 | 0.667103 | 6 | 0 | 6 |
| HBE1 | WDR38 | 0.659654 | 3 | 0 | 3 |
| HBE1 | NAT8B | 0.654338 | 4 | 0 | 3 |
| HBE1 | C4BPA | 0.650616 | 5 | 0 | 5 |
| HBE1 | LHX9 | 0.649892 | 3 | 0 | 3 |
| HBE1 | OR10H1 | 0.649156 | 5 | 0 | 5 |
| HBE1 | FSCN2 | 0.644781 | 4 | 0 | 4 |
| HBE1 | CLCN2 | 0.638973 | 4 | 0 | 4 |
| HBE1 | DUOXA2 | 0.638041 | 3 | 0 | 3 |
| HBE1 | RAI1 | 0.631379 | 6 | 0 | 5 |
| HBE1 | MOGAT2 | 0.628062 | 3 | 0 | 3 |
| HBE1 | RHBDL1 | 0.627555 | 4 | 0 | 3 |
| HBE1 | C1orf61 | 0.625372 | 6 | 0 | 6 |
| HBE1 | IQSEC3 | 0.621558 | 6 | 0 | 4 |
| HBE1 | NTNG1 | 0.619622 | 4 | 0 | 4 |
| HBE1 | DIO3 | 0.619461 | 3 | 0 | 3 |
| HBE1 | CHRNA2 | 0.619176 | 6 | 0 | 6 |
| HBE1 | NTSR2 | 0.617612 | 4 | 0 | 4 |
| HBE1 | KIR2DS3 | 0.612939 | 5 | 0 | 4 |
For details and further investigation, click here
