| Full name: transmembrane p24 trafficking protein 1 | Alias Symbol: ST2L|MGC1270|IL1RL1LG|Il1rl1l|p24gamma1|p24g1 | ||
| Type: protein-coding gene | Cytoband: 19p13.2 | ||
| Entrez ID: 11018 | HGNC ID: HGNC:17291 | Ensembl Gene: ENSG00000099203 | OMIM ID: 605395 |
| Drug and gene relationship at DGIdb | |||
Expression of TMED1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMED1 | 11018 | 203679_at | 0.2462 | 0.3751 | |
| GSE20347 | TMED1 | 11018 | 203679_at | 0.2446 | 0.0046 | |
| GSE23400 | TMED1 | 11018 | 203679_at | 0.2545 | 0.0000 | |
| GSE26886 | TMED1 | 11018 | 203679_at | 0.1693 | 0.3267 | |
| GSE29001 | TMED1 | 11018 | 203679_at | 0.5688 | 0.0733 | |
| GSE38129 | TMED1 | 11018 | 203679_at | 0.3566 | 0.0013 | |
| GSE45670 | TMED1 | 11018 | 203679_at | 0.3321 | 0.0039 | |
| GSE53622 | TMED1 | 11018 | 41857 | 0.2978 | 0.0000 | |
| GSE53624 | TMED1 | 11018 | 41857 | 0.3914 | 0.0000 | |
| GSE63941 | TMED1 | 11018 | 203679_at | -0.8749 | 0.0066 | |
| GSE77861 | TMED1 | 11018 | 203679_at | 0.1014 | 0.4804 | |
| GSE97050 | TMED1 | 11018 | A_24_P164731 | 0.2461 | 0.2770 | |
| SRP007169 | TMED1 | 11018 | RNAseq | -0.2613 | 0.4811 | |
| SRP008496 | TMED1 | 11018 | RNAseq | -0.0479 | 0.8714 | |
| SRP064894 | TMED1 | 11018 | RNAseq | 1.1934 | 0.0003 | |
| SRP133303 | TMED1 | 11018 | RNAseq | 0.3436 | 0.0083 | |
| SRP159526 | TMED1 | 11018 | RNAseq | 0.3296 | 0.1716 | |
| SRP193095 | TMED1 | 11018 | RNAseq | 0.1082 | 0.2938 | |
| SRP219564 | TMED1 | 11018 | RNAseq | 0.9250 | 0.0077 | |
| TCGA | TMED1 | 11018 | RNAseq | 0.0975 | 0.1093 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TMED1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMED1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMED1 | 11018 | 4 | 2 | 24 | |
| GSE20123 | TMED1 | 11018 | 3 | 1 | 26 | |
| GSE43470 | TMED1 | 11018 | 2 | 6 | 35 | |
| GSE46452 | TMED1 | 11018 | 47 | 1 | 11 | |
| GSE47630 | TMED1 | 11018 | 4 | 7 | 29 | |
| GSE54993 | TMED1 | 11018 | 16 | 3 | 51 | |
| GSE54994 | TMED1 | 11018 | 6 | 13 | 34 | |
| GSE60625 | TMED1 | 11018 | 9 | 0 | 2 | |
| GSE74703 | TMED1 | 11018 | 2 | 4 | 30 | |
| GSE74704 | TMED1 | 11018 | 0 | 1 | 19 | |
| TCGA | TMED1 | 11018 | 15 | 14 | 67 |
Total number of gains: 108; Total number of losses: 52; Total Number of normals: 328.
Somatic mutations of TMED1:
Generating mutation plots.
Highly correlated genes for TMED1:
Showing top 20/251 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMED1 | MCOLN1 | 0.674614 | 3 | 0 | 3 |
| TMED1 | GNL1 | 0.666592 | 3 | 0 | 3 |
| TMED1 | LAT2 | 0.665802 | 3 | 0 | 3 |
| TMED1 | TRPM2 | 0.662812 | 5 | 0 | 4 |
| TMED1 | ASPHD2 | 0.659507 | 3 | 0 | 3 |
| TMED1 | TMED6 | 0.651631 | 3 | 0 | 3 |
| TMED1 | RHPN1 | 0.647924 | 4 | 0 | 4 |
| TMED1 | COL16A1 | 0.646193 | 3 | 0 | 3 |
| TMED1 | CLEC11A | 0.645921 | 3 | 0 | 3 |
| TMED1 | SYCE1L | 0.642599 | 4 | 0 | 4 |
| TMED1 | NTNG2 | 0.641992 | 3 | 0 | 3 |
| TMED1 | LSAMP-AS1 | 0.632608 | 3 | 0 | 3 |
| TMED1 | TIGD5 | 0.631023 | 3 | 0 | 3 |
| TMED1 | PPP6R1 | 0.625104 | 3 | 0 | 3 |
| TMED1 | WDR83 | 0.622071 | 5 | 0 | 4 |
| TMED1 | ZFAT | 0.621135 | 4 | 0 | 3 |
| TMED1 | FAM24B | 0.619392 | 4 | 0 | 3 |
| TMED1 | EED | 0.615237 | 3 | 0 | 3 |
| TMED1 | SDF2L1 | 0.611306 | 4 | 0 | 4 |
| TMED1 | DERL1 | 0.609303 | 5 | 0 | 4 |
For details and further investigation, click here
