| Full name: lysyl oxidase like 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2p13.1 | ||
| Entrez ID: 84695 | HGNC ID: HGNC:13869 | Ensembl Gene: ENSG00000115318 | OMIM ID: 607163 |
| Drug and gene relationship at DGIdb | |||
Expression of LOXL3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LOXL3 | 84695 | 228253_at | -0.0188 | 0.9797 | |
| GSE26886 | LOXL3 | 84695 | 228253_at | 0.1854 | 0.2477 | |
| GSE45670 | LOXL3 | 84695 | 228253_at | -0.1900 | 0.2215 | |
| GSE53622 | LOXL3 | 84695 | 82077 | 0.9376 | 0.0000 | |
| GSE53624 | LOXL3 | 84695 | 82077 | 0.9917 | 0.0000 | |
| GSE63941 | LOXL3 | 84695 | 228253_at | -2.1474 | 0.0000 | |
| GSE77861 | LOXL3 | 84695 | 228253_at | -0.0305 | 0.8100 | |
| GSE97050 | LOXL3 | 84695 | A_24_P88763 | 0.2277 | 0.4453 | |
| SRP007169 | LOXL3 | 84695 | RNAseq | 2.7422 | 0.0032 | |
| SRP064894 | LOXL3 | 84695 | RNAseq | 0.9041 | 0.0000 | |
| SRP133303 | LOXL3 | 84695 | RNAseq | 0.2953 | 0.1764 | |
| SRP159526 | LOXL3 | 84695 | RNAseq | 1.0534 | 0.0304 | |
| SRP193095 | LOXL3 | 84695 | RNAseq | 0.9648 | 0.0000 | |
| SRP219564 | LOXL3 | 84695 | RNAseq | 0.5845 | 0.2628 | |
| TCGA | LOXL3 | 84695 | RNAseq | 0.1900 | 0.2184 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by LOXL3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LOXL3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LOXL3 | 84695 | 9 | 2 | 19 | |
| GSE20123 | LOXL3 | 84695 | 10 | 2 | 18 | |
| GSE43470 | LOXL3 | 84695 | 4 | 0 | 39 | |
| GSE46452 | LOXL3 | 84695 | 2 | 3 | 54 | |
| GSE47630 | LOXL3 | 84695 | 7 | 0 | 33 | |
| GSE54993 | LOXL3 | 84695 | 0 | 6 | 64 | |
| GSE54994 | LOXL3 | 84695 | 10 | 0 | 43 | |
| GSE60625 | LOXL3 | 84695 | 0 | 3 | 8 | |
| GSE74703 | LOXL3 | 84695 | 4 | 0 | 32 | |
| GSE74704 | LOXL3 | 84695 | 8 | 0 | 12 | |
| TCGA | LOXL3 | 84695 | 37 | 2 | 57 |
Total number of gains: 91; Total number of losses: 18; Total Number of normals: 379.
Somatic mutations of LOXL3:
Generating mutation plots.
Highly correlated genes for LOXL3:
Showing top 20/378 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LOXL3 | PDGFRL | 0.706547 | 6 | 0 | 6 |
| LOXL3 | AZIN2 | 0.699209 | 3 | 0 | 3 |
| LOXL3 | EDNRB | 0.696743 | 3 | 0 | 3 |
| LOXL3 | SCN3A | 0.693311 | 3 | 0 | 3 |
| LOXL3 | FAT4 | 0.690932 | 3 | 0 | 3 |
| LOXL3 | VCAM1 | 0.690341 | 4 | 0 | 3 |
| LOXL3 | PRRX1 | 0.685682 | 6 | 0 | 5 |
| LOXL3 | SCG5 | 0.681893 | 5 | 0 | 5 |
| LOXL3 | ARMC9 | 0.677356 | 3 | 0 | 3 |
| LOXL3 | RARRES2 | 0.676869 | 7 | 0 | 6 |
| LOXL3 | GPC6 | 0.675167 | 5 | 0 | 4 |
| LOXL3 | SCG2 | 0.671414 | 4 | 0 | 4 |
| LOXL3 | RPS6KA2 | 0.670062 | 3 | 0 | 3 |
| LOXL3 | NOG | 0.669791 | 3 | 0 | 3 |
| LOXL3 | COLEC12 | 0.668431 | 4 | 0 | 4 |
| LOXL3 | GPX8 | 0.668278 | 4 | 0 | 4 |
| LOXL3 | AMPD2 | 0.665446 | 4 | 0 | 4 |
| LOXL3 | FBN1 | 0.664509 | 4 | 0 | 3 |
| LOXL3 | DPY19L1 | 0.663689 | 3 | 0 | 3 |
| LOXL3 | ISLR | 0.663564 | 6 | 0 | 5 |
For details and further investigation, click here
