| Full name: ATPase family AAA domain containing 3B | Alias Symbol: TOB3|KIAA1273 | ||
| Type: protein-coding gene | Cytoband: 1p36.33 | ||
| Entrez ID: 83858 | HGNC ID: HGNC:24007 | Ensembl Gene: ENSG00000160072 | OMIM ID: 612317 |
| Drug and gene relationship at DGIdb | |||
Expression of ATAD3B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATAD3B | 83858 | 223617_x_at | 0.4868 | 0.1008 | |
| GSE26886 | ATAD3B | 83858 | 227237_x_at | 0.3152 | 0.0304 | |
| GSE45670 | ATAD3B | 83858 | 223617_x_at | 0.2795 | 0.0128 | |
| GSE53622 | ATAD3B | 83858 | 40016 | 0.2555 | 0.0000 | |
| GSE53624 | ATAD3B | 83858 | 40016 | 0.6854 | 0.0000 | |
| GSE63941 | ATAD3B | 83858 | 227237_x_at | 0.3884 | 0.0326 | |
| GSE77861 | ATAD3B | 83858 | 227237_x_at | -0.0013 | 0.9932 | |
| GSE97050 | ATAD3B | 83858 | A_33_P3385477 | 0.3525 | 0.2575 | |
| SRP007169 | ATAD3B | 83858 | RNAseq | 0.1071 | 0.8575 | |
| SRP008496 | ATAD3B | 83858 | RNAseq | -0.0965 | 0.7824 | |
| SRP064894 | ATAD3B | 83858 | RNAseq | 0.8879 | 0.0001 | |
| SRP133303 | ATAD3B | 83858 | RNAseq | 0.2844 | 0.0720 | |
| SRP159526 | ATAD3B | 83858 | RNAseq | 0.4515 | 0.2753 | |
| SRP193095 | ATAD3B | 83858 | RNAseq | 0.6817 | 0.0000 | |
| SRP219564 | ATAD3B | 83858 | RNAseq | 0.4966 | 0.2391 | |
| TCGA | ATAD3B | 83858 | RNAseq | 0.1845 | 0.0241 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ATAD3B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATAD3B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATAD3B | 83858 | 3 | 7 | 20 | |
| GSE20123 | ATAD3B | 83858 | 3 | 6 | 21 | |
| GSE43470 | ATAD3B | 83858 | 3 | 5 | 35 | |
| GSE46452 | ATAD3B | 83858 | 7 | 1 | 51 | |
| GSE47630 | ATAD3B | 83858 | 8 | 4 | 28 | |
| GSE54993 | ATAD3B | 83858 | 2 | 2 | 66 | |
| GSE54994 | ATAD3B | 83858 | 15 | 2 | 36 | |
| GSE60625 | ATAD3B | 83858 | 0 | 0 | 11 | |
| GSE74703 | ATAD3B | 83858 | 3 | 3 | 30 | |
| GSE74704 | ATAD3B | 83858 | 3 | 0 | 17 | |
| TCGA | ATAD3B | 83858 | 14 | 20 | 62 |
Total number of gains: 61; Total number of losses: 50; Total Number of normals: 377.
Somatic mutations of ATAD3B:
Generating mutation plots.
Highly correlated genes for ATAD3B:
Showing top 20/605 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATAD3B | ATAD3A | 0.859446 | 8 | 0 | 8 |
| ATAD3B | PRKD2 | 0.795817 | 3 | 0 | 3 |
| ATAD3B | RRBP1 | 0.749978 | 3 | 0 | 3 |
| ATAD3B | MRPL12 | 0.734438 | 3 | 0 | 3 |
| ATAD3B | FUOM | 0.723081 | 3 | 0 | 3 |
| ATAD3B | NOC2L | 0.716122 | 6 | 0 | 5 |
| ATAD3B | WDR90 | 0.708993 | 4 | 0 | 3 |
| ATAD3B | SGTA | 0.70115 | 3 | 0 | 3 |
| ATAD3B | TUBGCP2 | 0.691596 | 4 | 0 | 4 |
| ATAD3B | ARMC6 | 0.687046 | 6 | 0 | 6 |
| ATAD3B | AP2A1 | 0.683109 | 4 | 0 | 3 |
| ATAD3B | MIIP | 0.67947 | 5 | 0 | 4 |
| ATAD3B | CALR | 0.675547 | 4 | 0 | 4 |
| ATAD3B | DUS1L | 0.675329 | 5 | 0 | 4 |
| ATAD3B | POLR3H | 0.672698 | 3 | 0 | 3 |
| ATAD3B | TOMM40 | 0.672237 | 5 | 0 | 4 |
| ATAD3B | B4GALT2 | 0.672204 | 4 | 0 | 3 |
| ATAD3B | SLC45A3 | 0.670525 | 3 | 0 | 3 |
| ATAD3B | NOP14 | 0.670076 | 4 | 0 | 3 |
| ATAD3B | SSTR5 | 0.669417 | 3 | 0 | 3 |
For details and further investigation, click here
