| Full name: solute carrier family 45 member 3 | Alias Symbol: IPCA-6|prostein|IPCA-2|IPCA-8 | ||
| Type: protein-coding gene | Cytoband: 1q32.1 | ||
| Entrez ID: 85414 | HGNC ID: HGNC:8642 | Ensembl Gene: ENSG00000158715 | OMIM ID: 605097 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC45A3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC45A3 | 85414 | 228696_at | 0.7329 | 0.1721 | |
| GSE26886 | SLC45A3 | 85414 | 228696_at | 0.5059 | 0.0013 | |
| GSE45670 | SLC45A3 | 85414 | 228696_at | 0.0766 | 0.6139 | |
| GSE53622 | SLC45A3 | 85414 | 33914 | -0.1056 | 0.5853 | |
| GSE53624 | SLC45A3 | 85414 | 33914 | 0.0111 | 0.9423 | |
| GSE63941 | SLC45A3 | 85414 | 228696_at | 0.4931 | 0.1781 | |
| GSE77861 | SLC45A3 | 85414 | 228696_at | 0.0288 | 0.8884 | |
| GSE97050 | SLC45A3 | 85414 | A_24_P208345 | 0.3062 | 0.2709 | |
| SRP007169 | SLC45A3 | 85414 | RNAseq | 0.5840 | 0.4408 | |
| SRP064894 | SLC45A3 | 85414 | RNAseq | 0.0392 | 0.8932 | |
| SRP133303 | SLC45A3 | 85414 | RNAseq | -0.5202 | 0.0060 | |
| SRP159526 | SLC45A3 | 85414 | RNAseq | 0.9096 | 0.0137 | |
| SRP193095 | SLC45A3 | 85414 | RNAseq | -0.4914 | 0.2502 | |
| SRP219564 | SLC45A3 | 85414 | RNAseq | 1.2326 | 0.0339 | |
| TCGA | SLC45A3 | 85414 | RNAseq | -0.3880 | 0.0003 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SLC45A3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC45A3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC45A3 | 85414 | 11 | 0 | 19 | |
| GSE20123 | SLC45A3 | 85414 | 11 | 0 | 19 | |
| GSE43470 | SLC45A3 | 85414 | 7 | 0 | 36 | |
| GSE46452 | SLC45A3 | 85414 | 3 | 1 | 55 | |
| GSE47630 | SLC45A3 | 85414 | 14 | 0 | 26 | |
| GSE54993 | SLC45A3 | 85414 | 0 | 6 | 64 | |
| GSE54994 | SLC45A3 | 85414 | 15 | 0 | 38 | |
| GSE60625 | SLC45A3 | 85414 | 0 | 0 | 11 | |
| GSE74703 | SLC45A3 | 85414 | 7 | 0 | 29 | |
| GSE74704 | SLC45A3 | 85414 | 5 | 0 | 15 | |
| TCGA | SLC45A3 | 85414 | 43 | 5 | 48 |
Total number of gains: 116; Total number of losses: 12; Total Number of normals: 360.
Somatic mutations of SLC45A3:
Generating mutation plots.
Highly correlated genes for SLC45A3:
Showing top 20/135 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC45A3 | NAA38 | 0.746794 | 3 | 0 | 3 |
| SLC45A3 | MYPOP | 0.737098 | 3 | 0 | 3 |
| SLC45A3 | YDJC | 0.73372 | 3 | 0 | 3 |
| SLC45A3 | RUVBL1 | 0.730941 | 3 | 0 | 3 |
| SLC45A3 | ELK1 | 0.730889 | 3 | 0 | 3 |
| SLC45A3 | ZNF786 | 0.729443 | 3 | 0 | 3 |
| SLC45A3 | MUC16 | 0.721745 | 3 | 0 | 3 |
| SLC45A3 | POP7 | 0.70134 | 3 | 0 | 3 |
| SLC45A3 | ALKBH4 | 0.699503 | 4 | 0 | 3 |
| SLC45A3 | MED19 | 0.697302 | 3 | 0 | 3 |
| SLC45A3 | NUP62 | 0.693085 | 3 | 0 | 3 |
| SLC45A3 | IGFBPL1 | 0.6917 | 3 | 0 | 3 |
| SLC45A3 | DPM3 | 0.689066 | 3 | 0 | 3 |
| SLC45A3 | SYNPO | 0.686684 | 3 | 0 | 3 |
| SLC45A3 | ATG2A | 0.681577 | 3 | 0 | 3 |
| SLC45A3 | SIX1 | 0.674867 | 3 | 0 | 3 |
| SLC45A3 | ATAD3B | 0.670525 | 3 | 0 | 3 |
| SLC45A3 | UBA52 | 0.668676 | 3 | 0 | 3 |
| SLC45A3 | CPSF4 | 0.667262 | 3 | 0 | 3 |
| SLC45A3 | CLPP | 0.65929 | 3 | 0 | 3 |
For details and further investigation, click here
